Journals / Türkiye Parazitoloji Dergisi / 2004 / Cilt: 28 - Sayı: 1

Spesific IgE levels in patients with cystic echinococcosis

Kistik ekinokokkozis hastalarında spesifik IgE düzeyleri

Pages
21–23
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclusion, our findings supported the theory that specific IgE levels in the diagnosis of cystic echinococcosis is low in sensitivity but may be used in follow-up of disease in patients with CE with high specific IgE levels.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The aim of this study was to demonstrate the diagnostic value of specific IgE antibodies in patients with cystic echinococcosis (CE).
📊
Key Findings & Data:For this, 28 non-surgical patients with cysts shown by radiological examination and who were found to be CE positive with commercial IHA and homemade ELISA tests were included in this study.
💡
Conclusion & Impact:In conclusion, our findings supported the theory that specific IgE levels in the diagnosis of cystic echinococcosis is low in sensitivity but may be used in follow-up of disease in patients with CE with high specific IgE levels.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The aim of this study was to demonstrate the diagnostic value of specific IgE antibodies in patients with cystic echinococcosis (CE). For this, 28 non-surgical patients with cysts shown by radiological examination and who were found to be CE positive with commercial IHA and homemade ELISA tests were included in this study. A comparison of the specific IgE levels of these selected 28 patients was made using commercial and homemade ELISA tests. Specific IgE positivity was detected with the commercial kit in 11 and with the homemade ELISA in 13 of the 28 patients who had been diagnosed with cystic echinococcosis using serological tests and radiological examination. In conclusion, our findings supported the theory that specific IgE levels in the diagnosis of cystic echinococcosis is low in sensitivity but may be used in follow-up of disease in patients with CE with high specific IgE levels.

Özet

Bu çalışma kistik ekinokokkozisli (KE) hastalarda spesifik IgG antikorlarının tanı değerinin ortaya konması için planlanmıştır. Bu amaçla radyolojik olarak kist gösterilmiş fakat öpere edilmemiş ve serolojik olarak ticari IHA ve ev yapımı ELISA testleri ile KE pozitifli saptanan 28 hasta çalışmaya alınmıştır. Bu 28 hastanın spesifik IgE düzeyleri ticari test kiti ve ev yapımı ELISA kiti ile karşılaştırmalı olarak araştırılmıştır. Serolojik ve radyolojik olarak KE tanısı konan 28 hastanın 11 'inde ticari kit ile 13'ünde ev yapımı ELISA testi ile pozitif spesifik IgE düzeyleri saptanmıştır. Sonuç olarak bulgularımız, spesifik IgE düzeylerinin KE tanısında duyarlılığının düşük olduğunu ve yüksek saptanan hastalarda ancak hastalığın takibinde kullanılabileceği teorisi desteklemektedir.

🔖

Cite This Article

DEMİRCİ, M., KAYA, S., ARIDOĞAN, B. C., YÖNDEN, C., ÖNAL, S. (2022). Spesific IgE levels in patients with cystic echinococcosis. Türkiye Parazitoloji Dergisi, Cilt: 28 - Sayı: 1, 21–23. https://ajindex.com/articles/630890

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Altıntaş N, Yazar S, 1999. Cystic Echinococcosis (CE)'de tanı. T Parazitol Derg, 23(2): 160-68
  2. Budak S, 1991. Kist Hidatid'in Epidemiyolojisi. İnsanlarda ve hayvanlarda kist hidatid. Türkiye Parazitoloji Derneği Yayını No:10, 55-64
  3. Bulut V, Ilhan F, Yücel AY, Onal S, Ilhan Y, Godekmerdan A, 2001. Immunological follow-up of hydatid cyst cases. Mem Inst Oswaldo Cruz, 96(5):669-71
  4. Dessaint JP, Bout D, Wattre P, Capron A, 1975. Quantitative determination of specific IgE antibodies to Echinococcus granulosus and IgE levels in sera from patients with hydatid disease. Immunology, 29:813 23.1-6
  5. Di Comite G, Dognini G, Gaiera G, Ieri R, Praderio L, 2000. Acute echinococcosis: a case report. J Clin Microbiol, 38:4679- 4680
  6. Force L, Torres JM, Carrillo A, Busca J, 1992. Evaluation of eight serological tests in the diagnosis of human echinococcosis and follow-up. Clin Infect Dis, 15(3):473-80
  7. Hernandez A, Borras R, Mir A, 1997. Analysis of cytokine and specific antibody profiles in hydatid patients with primary and infection and relapse of disease. Parasite Immunol, 19:553- 61
  8. Markell EK, Voge M, John DT, 1992. The Cestodes, in: Medical Parasitology, Ed S Ozmat, 7th ed. WB Saunders Company p: 226-60
  9. Rigano R, Ioppolo S, Ortona E, Margutti P, Profumo E, Ali MD, Di Vico B, Teggi A, Siracusano A, 2002. Long-term serological evaluation of patients with cystic echinococcosis treated with benzimidazole carbamates. Clin Exp Immunol, 29(3): 485-92
  10. Rigano R, Profumo E, Di Felice G, Ortona E, Teggi A, Siracusano A, 1995. In vitro production of cytokines by peripheral blood mononuclear cells from hydatid patients. Clin Exp Immunol, 99:433 -9
  11. Scott P, Pearce EJ, Cheever AW, 1989. Role of cytokines and CD4+ T-cell subsets in the regulation of parasite immunity and disease. Immunol Rev, 112:161 82
  12. Sjolander A, Guisantes JA, Torres-Rodriguez JM, Schroder H, 1989. The diagnosis of human hydatidosis by measurement of specific IgE antibody by enzyme immunoassay. Scand J Infect Dis, 21(2):213-8
  13. Torcal J, Navarro-Zorraquino M, Lozano R, Larrad L, Salinas J, Ferrer C, Roman J, Pastör C, 1996. Immune response and in vivo production of cytokines in patients with liver hydatidosis. Clin Exp Immunol, 106:317-322
  14. Unat EK, 1982. Tıp Parazitolojisi, 3. Baskı, Istanbul, İ.Ü. Cerrahpaşa Tıp Fakültesi Yayınları Dekanlık No: 113, s: 471- 497.