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Journals / Türkiye Tıp Dergisi Dahili Tıp Bilimleri / 1999 / Cilt: 6 - Sayı: 2

The effects of hypothyroidism on plasma levels of zinc in rats

Ratlarda hipotiroidizmin plazma çinko düzeylerine etkisi

Kasım BALTACI
Osman DOĞRU
Rasim MOĞULKOÇ
Selim KUTLU
Süleyman SANDAL
Şeref BEDİZ
Pages
105–109
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Plasma levels of T3 and T4 were significantly low in both thyroidectomized and PTU groups compared to controls (p

📌 3 Key Takeaways

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Objective & Hypothesis:The aim of this study was to investigate the effects of thyroidectomy and propylthiouracil induced (PTU) hypothyroidism on plasma levels of zinc and thyroid hormones in rats.
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Key Findings & Data:A total of 18 rats, consisting control (n=6), thyroidectomized (n=6) and PTU (n=6) groups, were used in this study and plasma levels ofT3, T4 and Zn levels were detected using RIA and automatic absorption spectrofotometry methods, respectively.
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Conclusion & Impact:Plasma levels of T3 and T4 were significantly low in both thyroidectomized and PTU groups compared to controls (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The aim of this study was to investigate the effects of thyroidectomy and propylthiouracil induced (PTU) hypothyroidism on plasma levels of zinc and thyroid hormones in rats. A total of 18 rats, consisting control (n=6), thyroidectomized (n=6) and PTU (n=6) groups, were used in this study and plasma levels ofT3, T4 and Zn levels were detected using RIA and automatic absorption spectrofotometry methods, respectively. Plasma levels of T3 and T4 were significantly low in both thyroidectomized and PTU groups compared to controls (p

Özet

Bu çalışmanın amacı, tiroidektomi veyapropiltiyourasil (PTU) uygulamasıyla hipotiroidizm oluşturulmuş raflarda tiroid hormonları ile plazma çinko düzeyleri arasındaki ilişkiyi araştırmaktır. Kontrol (n=6), tiroidektomi (n=6) ve PTU (n=6) olmak üzere toplam 18 rat üzerinde gerçekleştirilen çalışmada, bütün grupların plazma T3, T4 (RIA yöntemi ile) ve çinko düzeyleri (atomik absorpsiyon spektrofotometresi ile) tayin edildi. Tiroidektomi ve PTU gruplarının plazma T3 ve T4 düzeyleri beklenildiği gibi kontrol grubuna oranla düşük bulundu (p

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Cite This Article

BALTACI, K., DOĞRU, O., MOĞULKOÇ, R., KUTLU, S., SANDAL, S., BEDİZ, Ş. (2022). The effects of hypothyroidism on plasma levels of zinc in rats. Türkiye Tıp Dergisi Dahili Tıp Bilimleri, Cilt: 6 - Sayı: 2, 105–109. https://ajindex.com/articles/630849