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Journals / Türk Kardiyoloji Derneği Arşivi / 2004 / Cilt: 32 - Sayı: 8

P wave duration and P wave dispersion in hyperthyroidism: Effect of antithyroid treatment

Hipertiroidide P dalga süresi ve P dalga dispersiyonu: Antitiroid tedavinin etkisi

Ümit GÜRAY
Hakan ALTAY
Yeşim GÜRAY
Serdar GÜLER
Halil KISACIK
Şule KORKMAZ
M. Birhan YILMAZ
Pages
556–563
Publication Date
2022-11-05
DOI
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⚡ TL;DR(Too Long; Didn't Read)

P max values were found to be significantly longer in both PAF+ (114.8±11.6 ms) and PAF- (105.6±11ms) patient groups as compared to controls (91±7.6 ms; p

📌 3 Key Takeaways

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Objective & Hypothesis:Atrial fibrillation is frequently encountered in patients with hyperthyroidism.
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Key Findings & Data:Previously, it was shown that prolonged maximum P wave duration and increased P wave dispersion on 12-lead surface electrocardiograms (ECG) are closely related to the development of paroxysmal atrial fibrillation (PAF).
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Conclusion & Impact:P max values were found to be significantly longer in both PAF+ (114.8±11.6 ms) and PAF- (105.6±11ms) patient groups as compared to controls (91±7.6 ms; p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Atrial fibrillation is frequently encountered in patients with hyperthyroidism. Previously, it was shown that prolonged maximum P wave duration and increased P wave dispersion on 12-lead surface electrocardiograms (ECG) are closely related to the development of paroxysmal atrial fibrillation (PAF). In this study, these P wave parameters were measured from 12-lead surface ECG in hyperthyroid patients with or without PAF during sinus rhythm and compared to euthyroid controls. In addition, influence of pharmacologic antithyroid therapy on these P wave parameters was investigated. Fifty-two hyperthyroid patients were included in the study. All patients underwent 24-hour Holter recordings and then, patients were divided into two groups according to the presence (PAF+; n=29) or absence (PAF-; n=23) of PAF. Maximum P wave duration (P max), minimum P wave duration (P min) were measured from the 12-lead surface ECG and P dispersion (PWD=P max-P min) values were then calculated. P max values were found to be significantly longer in both PAF+ (114.8±11.6 ms) and PAF- (105.6±11ms) patient groups as compared to controls (91±7.6 ms; p

Özet

Hipertiroidi hastalarında atriyal fibrilasyona (AF) normal popülasyona göre daha sık rastlanmaktadır. On iki derivasyonlu yüzey elektrokardiyogramından (EKG) hesaplanan maksimum P dalga süresive P dalga dispersiyonunun (PDD) uzamasının, paroksismal atriyal fibrilasyon (PAF) gelişimi ile yakından ilişkili olduğu bilinmektedir. Bu çalışmada, hipertiroidi tanısı almış PAF'ı olan ve olmayan hastalarda bu P dalga parametreleri, ötiroid sağlıklı bireylerle karşılaştırılmıştır. Ayrıca antitiroid tedavi sonrası bahsedilen P dalga parametrelerindeki değişim incelenmiştir. Çalışmamıza 52 ardışık hipertiroidi tanısı alan hasta dahil edildi. Tüm hastaların 24 saatlik Holter kayıtları alındı ve PAF varlığına göre bu hastalar iki gruba ayrıldı (PAF+ 29 hasta, PAF- 23 hasta). Tüm hastaların maksimum P dalga süresi (P mak), minimum P dalga süresi (P min) 12-derivasyonlu yüzey EKG kayıtlarından ölçüldü. PDD, P mak'dan P min çıkarılarak hesaplandı. Bulgularımıza göre hem PAF+ hem de PAF- hipertiroidi grubunun P mak değerlerinin kontrol grubundan daha uzun olduğu saptandı (sırasıyla, 114.8±11.6 msn; 105.6±11msn; 91±7.6 msn, p

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Cite This Article

GÜRAY, Ü., ALTAY, H., GÜRAY, Y., GÜLER, S., KISACIK, H., KORKMAZ, Ş., YILMAZ, M. B. (2022). P wave duration and P wave dispersion in hyperthyroidism: Effect of antithyroid treatment. Türk Kardiyoloji Derneği Arşivi, Cilt: 32 - Sayı: 8, 556–563. https://ajindex.com/articles/628649

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