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Journals / Türkiye Aile Hekimliği Dergisi / 2017 / Cilt: 21 - Sayı: 1

A rare complication of warfarin: late onset warfarin induced skin necrosis

Warfarine bağlı nadir bir komplikasyon; geç başlangıçlı warfarin ilişkili deri nekrozu

Telat KELEŞ
Yakup ALSANCAK
Tahir DURMAZ
Serkan SİVRİ
Engin BOZKURT
Pages
41–43
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In the treatment of this complication, parenterally and the new oral anticoagulant agents are the other treatment options.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Warfarin is an oral anticoagulant, can lead to skin necrosis quite rarely that is a serious complication.
📊
Key Findings & Data:However this complica- tion is observed usually during the first 10 days of treatment, the presented case, as a result of inappropriate drug withdrawal and restarting, has emerged after two years from the start of treatment as late onset.
💡
Conclusion & Impact:In the treatment of this complication, parenterally and the new oral anticoagulant agents are the other treatment options.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Warfarin is an oral anticoagulant, can lead to skin necrosis quite rarely that is a serious complication. However this complica- tion is observed usually during the first 10 days of treatment, the presented case, as a result of inappropriate drug withdrawal and restarting, has emerged after two years from the start of treatment as late onset. After stopping the warfarin therapy , the patient was treated with oral acetylsalicylic acid and skin necro- sis regressed within days without recurrence. In the treatment of this complication, parenterally and the new oral anticoagulant agents are the other treatment options.

Özet

Bir oral antikoagülan olan warfarin, oldukça nadir olarak, ciddi bir komplikasyon olan deri nekrozuna neden olabilmektedir. Genellikle tedavinin ilk 10 gününde izlenen bu komplikasyon, sunduğumuz vakada uygunsuz ilaç kesilmesi ve tekrar başlanması sonucu, geç başlangıçlı şekilde, tedavi başlangıcından 2 yıl sonra karşımıza çıkmıştır. Warfarin tedavisini kestikten sonra, oral asetilsalisilik asit ile tedavi ettiğimiz bu vakada deri nekrozu nüks olmadan, günler içerisinde gerilemiştir. Bu komplikasyonun tedavisinde parenteral ve yeni oral antikoagülan ajanlar ise diğer tedavi seçeneklerini oluşturmaktadır.

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Cite This Article

KELEŞ, T., ALSANCAK, Y., DURMAZ, T., SİVRİ, S., BOZKURT, E. (2022). A rare complication of warfarin: late onset warfarin induced skin necrosis. Türkiye Aile Hekimliği Dergisi, Cilt: 21 - Sayı: 1, 41–43. https://ajindex.com/articles/626711

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