Journals / Türkiye Acil Tıp Dergisi / 2010 / Cilt: 10 - Sayı: 2

Baklofen aşırı dozu

Baclofen intoxication

Pages
86–89
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

An acutely confused or comatose patient is admitted to emergency department, baclofen intoxicitation should be kept in mind in the differential diagnosis.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Baclofen, a derivative of γ-aminobutyric acid, is used for symptomatic relief of skeletal muscle spasm and spasticity.
📊
Key Findings & Data:In this paper, we reported a case of 19 year-old female with baclofen overdose presenting to the emergency department with coma.
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Conclusion & Impact:An acutely confused or comatose patient is admitted to emergency department, baclofen intoxicitation should be kept in mind in the differential diagnosis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Baclofen, a derivative of γ-aminobutyric acid, is used for symptomatic relief of skeletal muscle spasm and spasticity. Overdose of this drug can cause profound central nervous system depression, including coma, hypotonia, respiratory depression, seizures, and cardiovascular effects. In this paper, we reported a case of 19 year-old female with baclofen overdose presenting to the emergency department with coma. She recovered and discharged after supportive care including mechanical ventilation. An acutely confused or comatose patient is admitted to emergency department, baclofen intoxicitation should be kept in mind in the differential diagnosis.

Özet

Baklofen bir gama-aminobütirik asit derivesidir; iskelet kas spazmında ve spastisitede semptomatik rahatlama için kullanılır. Bu ilacın aşırı dozları koma, hipotoni, solunum depresyonu, konvulsiyonu da içerecek şekilde santral sinir sistemi depresyonuna ve kardiyovasküler etkilere neden olabilir. Bu yazıda, acil servise özkıyım amaçlı baklofen aşırı alımı sonrası koma ile getirilen 19 yaşında kadın bir olgu sunuldu. Hasta mekanik vantilasyon dahil yapılan destek tedavi ile iyileşti ve taburcu oldu. Acil servise konfüzyon veya koma ile başvuran hastalarda, baklofen aşırı dozu ayırıcı tanıda akılda tutulmalıdır.

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Cite This Article

AYGENCEL, G., PAMUKÇU, G., KELEŞ, A., BİLDİK, F., DEMİRCAN, A., ÖZSARAÇ, M. (2022). Baklofen aşırı dozu. Türkiye Acil Tıp Dergisi, Cilt: 10 - Sayı: 2, 86–89. https://ajindex.com/articles/626065

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