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Journals / Türkiye'de Psikiyatri Derg. / 2006 / Cilt: 8 - Sayı: 1

Carbamazepine-induced hyponatremia and its consequences: A case report

Karbamazepin tedavisi sırasında gelişen hiponatremi ve sonuçları: Bir olgu sunumu

Fatih Volkan YÜKSEL
Erol GÖKA
Cebrail KISA
Çiğdem AYDEMİR
Pages
50–53
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In addition to the carbamazapine dosage, various factors, such as additional therapeutic agents usage, can affect the occurance of carbame- zepine-induced hyponatremia.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:A review of the literature since the beginning of carbamazepine usage for psychiatric and neurologic conditions reveals that hyponatremia is a frequently addressed issue.
📊
Key Findings & Data:The aim of this case report was to re-emphasize the hyponatremia side effect of carbamazepine, which is still an important psychotherapeutic agent and to review the literature on this issue.
💡
Conclusion & Impact:In addition to the carbamazapine dosage, various factors, such as additional therapeutic agents usage, can affect the occurance of carbame- zepine-induced hyponatremia.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

A review of the literature since the beginning of carbamazepine usage for psychiatric and neurologic conditions reveals that hyponatremia is a frequently addressed issue. The aim of this case report was to re-emphasize the hyponatremia side effect of carbamazepine, which is still an important psychotherapeutic agent and to review the literature on this issue. Carbamazepine therapy was initiated for the co-morbid Type I Bipolar Disorder in a Familial Diabetes Insipidus (Dl) case receiving desmopressin acetate (DDAVP). The hyponatremia case is presented with the aspects of the diagnostic and therapeutic process, laboratory investigational data, and clinical findings. The risk of hyponatremia seen as a side-effect of carbamazepine usage alone is potentiated with desmopressin acetate usage for a comorbid condition. In addition to the carbamazapine dosage, various factors, such as additional therapeutic agents usage, can affect the occurance of carbame- zepine-induced hyponatremia.

Özet

ite¬ratüre bakıldığında, hiponatremi konusunun sık işlendiği görülmektedir. Bu olgu sunumunda ruhsal bozukluklarda ilaç tedavileri içinde halen önemli bir yeri olan karbamazepin kullanımı ile ortaya çıkan hiponatremiye yeniden dikkati çekmek ve literatür bilgilerini gözden geçirmek amaçlanmıştır. Ailesel diabetes insipidus (Dİ) tedavisi için desmopressin asetat (DDAVP) almaktayken ortaya çıkan komorbid bipolar I bozukluk için karbamazepin tedavisi eklenmesi sonucu hiponatremi gelişen bir olgu tanı ve tedavi açısından değerlendirilme süreci, laboratuvar tetkikleri ve klinik bulgular doğrultusunda sunulmuştur. Karbamazepinin tek başına kullanımında hiponatremi yan etkisi görülmesinin yanı sıra, desmopressin asetat ile birlikte kullanımı hiponatremiye yol açma riskini artırmaktadır. Karbamazepinin hiponatremiye neden oluşunu hastaya, ilacın kullanım dozajı ve birlikte kullanılan diğer ilaçlara ait çeşitli faktörler etkileyebilir. Hayati önem taşıyan bu klinik tablonun tanınması ve acilen tedavisi ancak böyle bir durumun olabileceğinin tedavi öncesinde göz önünde bulundurulması ile gerçekleşebilir

🔖

Cite This Article

YÜKSEL, F. V., GÖKA, E., KISA, C., AYDEMİR, Ç. (2022). Carbamazepine-induced hyponatremia and its consequences: A case report. Türkiye'de Psikiyatri Derg., Cilt: 8 - Sayı: 1, 50–53. https://ajindex.com/articles/625919

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