Journals / Türk Hematoloji Onkoloji Dergisi / 2001 / Cilt: 11 - Sayı: 4

Tüberküloz ve hipoplastik pansitopeni

Tuberculosis and hypoplastic pancytopenia

Pages
223–226
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Antituberculosis therapy was begun but the patient died of superimposed nosocomial infection with XantHomonas maltophilia before the improvement of the hematologic parameters

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Although tuberculosis may represent with variable hematologic manifestations, pancytopenia with hypoplastic bone marrow is uncommon.
📊
Key Findings & Data:A 30 year old man was admitted to our hospital with low-grade fever, malaise, arthralgia, weight loss, productive cough and gingival bleeding.
💡
Conclusion & Impact:Antituberculosis therapy was begun but the patient died of superimposed nosocomial infection with XantHomonas maltophilia before the improvement of the hematologic parameters
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Although tuberculosis may represent with variable hematologic manifestations, pancytopenia with hypoplastic bone marrow is uncommon. Polymerase chain reaction (PCR) is the method of choice for the diagnosis of tuberculosis in cases where the suspicion is high. A 30 year old man was admitted to our hospital with low-grade fever, malaise, arthralgia, weight loss, productive cough and gingival bleeding. Anemia (Hb level 6.9 g/dl), leukopenia (wbc 0.7xl09/lt) and thrombocytopenia (platelet count 50xl09/lt) were detected. Clinical suspicion of milliary tuberculosis with the presenting features of fever, cough and chronic fibrotic changes on chest radiograms have prompted us to demonstrate the Mycobacterium tuberculosis bacilli. Using the PCR technique Mycobacterium tuberculosis bacilli DNA were detected in the bone marrow. Antituberculosis therapy was begun but the patient died of superimposed nosocomial infection with XantHomonas maltophilia before the improvement of the hematologic parameters

Özet

Tüberküloz değişik bulgularla karşımıza çıkabilse de, hipoplastik kemik iliği ve pansitopeni nadirdir. Bu gibi nadir rastlanan olgularda tüberküloz şüphesi varsa Polimeraz zincir reaksiyonu (PCR) yöntemi ile basil DNA varlığı gösterilebilmektedir. Bu vakada 30 yaşında erkek hasta hafif ateş, halsizlik, artralji, kilo kaybı ve balgamlı öksürük şikayetleri ile hastanemize başvurdu. Yapılan tetkiklerinde anemi (Hb seviyesi 6.9 g/dl), lökopeni (beyaz küre sayısı 0.7 x!09/lt) ve trombositopeni (platelet sayısı 50xl09/lt) tesbit edildi. Ateş, öksürük ve akciğer grafilerindeki kronik fibrotik görüntülerin varlığı ayırıcı tanıda miliyer tüberkülozu akla getirdi. Kemik iliğinde PCR yöntemi ile tüberküloz basili DNA'sı tesbit edildi. Antitüberküloz tedavi başlandı fakat hasta hematolojik parametrelerde düzelme olmadan, Xanthomonas maltophilia sepsisi ile kaybedildi.

🔖

Cite This Article

TÜTÜNCÜ, T., TUNCER, S., HAZNEDAROĞLU, İ. C., BAŞÇIL, N. (2022). Tüberküloz ve hipoplastik pansitopeni. Türk Hematoloji Onkoloji Dergisi, Cilt: 11 - Sayı: 4, 223–226. https://ajindex.com/articles/624780

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...