Journals / Türk Hematoloji Onkoloji Dergisi / 2004 / Cilt: 14 - Sayı: 2

Our radiotherapy results in soft tissue sarcomas

Yumuşak doku sarkomlarında radyoterapi sonuçlarımız

Pages
74–79
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Local control and overall survival rates at 4 years were 48% and 66%, respectively.

📌 3 Key Takeaways

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Objective & Hypothesis:Forty-one patients with the diagnosis of soft tissue sarcoma, treated with conservative surgery and radiotherapy were analysed in terms of treatment results and prognostic factors, retrospectively.
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Key Findings & Data:The most common histopathological subtypes were malignant fibrous histiocytoma (28%), leiomyosarcoma (19%) and liposarcoma (14%).
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Conclusion & Impact:Local control and overall survival rates at 4 years were 48% and 66%, respectively.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Forty-one patients with the diagnosis of soft tissue sarcoma, treated with conservative surgery and radiotherapy were analysed in terms of treatment results and prognostic factors, retrospectively. The most common histopathological subtypes were malignant fibrous histiocytoma (28%), leiomyosarcoma (19%) and liposarcoma (14%). Trunk (49%) and extremity (49%) were the most common locations with only one case with head and neck location. The patients were given total dose of 50-72 Gy (median 60 Gy) radiotherapy postoperatively, with teletherapy machines (Cobalt- 60 or 6-10 MV lineer accelerator). Local control and overall survival rates at 4 years were 48% and 66%, respectively. When analysed with multivariate analysis, tumor site and tumor size were found to be statistically significant prognostic factors influencing local control and overall survival, respectively.

Özet

Haziran 1996-Nisan 2003 tarihleri arasında organ koruyucu cerrahi ve radyoterapi uygulanan yumuşak doku sarkomu tanılı 41 erişkin hasta tedavi sonuçları ve prognostik faktörler yönünden retrospektif olarak değerlendirildi. Histopatolojik olarak en sık görülen tipler maliyn fibröz histiyositom (%28), leyomiyosarkom (%19) ve liposarkomdu (%14). En sık yerleşim yeri gövde (%49) ve ekstremite (%49) olup sadece bir olguda baş-boyun yerleşimi bulunmaktaydı. Hastalara teleterapi cihazları (kobalt 60 ve 6-10 MV lineer hızlandırıcı) ile toplam 50-72 Gy (mediyan 60 Gy) postoperatif radyoterapi uygulandı. Dört yıllık lokal kontrol ve genel sağkalım oranları sırasıyla %48 ve %66 olarak bulundu. Prognostik faktörlerin çok değişkenli analizinde yerleşim yeri lokal nüks açısından, tümör boyutu ise genel sağkalım açısından istatistiksel olarak anlamlı faktörler olarak bulundu.

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Cite This Article

GENÇ, M., ÇOLAK, F., YAVUZ, M. N., KÜÇÜKTÜLÜ, E., BAHAT, Z., CİMŞİTOĞLU, E., YAVUZ, A. A. (2022). Our radiotherapy results in soft tissue sarcomas. Türk Hematoloji Onkoloji Dergisi, Cilt: 14 - Sayı: 2, 74–79. https://ajindex.com/articles/624752

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