Journals / Turkish Journal of Medical Sciences / 2013 / Cilt: 43 - Sayı: 6

Headache in multiple sclerosis

Pages
1042–1049
Publication Date
2013-06-01
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: MS does not increase the prevalence of headaches, and headache types do not show any difference between MS patients and the control group.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Although multiple sclerosis (MS) can cause almost any neurological symptom, headaches are considered unusual.
📊
Key Findings & Data:Studies investigating the relationship between the 2 conditions have produced conflicting results.
💡
Conclusion & Impact:Conclusion: MS does not increase the prevalence of headaches, and headache types do not show any difference between MS patients and the control group.
🔬Design:Survey & Empirical Study
📍Scope:Comprehensive Sample
⚙️Variables:Key words: Multiple sclerosis · headache · prevalence

Abstract

Although multiple sclerosis (MS) can cause almost any neurological symptom, headaches are considered unusual. Studies investigating the relationship between the 2 conditions have produced conflicting results. The primary aim of this study was to test whether there was a difference between patients with MS (Group 1) and the control group (Group 2, patients with psoriasis and myasthenia gravis, diseases not affecting the central nervous system) in terms of the prevalence and types of primary headache. Materials and methods: A total of 139 patients with MS and 59 patients in the control group were included. The patients underwent a complete neurological examination and functional systems were assessed according to the functional system scores of Kurtzke. A semistructured interview guided by a questionnaire about headache was applied. Results: We found the life-long prevalence of primary headaches as 74.8% in patients with MS and as 71.2% in the control group. The prevalence of migraine and tension-type headaches did not show a significant difference between the 2 groups before the disease (P = 0.43), after the onset of disease (P = 0.18), or during the attack (P = 0.097). Conclusion: MS does not increase the prevalence of headaches, and headache types do not show any difference between MS patients and the control group.

Özet

Although multiple sclerosis (MS) can cause almost any neurological symptom, headaches are considered unusual. Studies investigating the relationship between the 2 conditions have produced conflicting results. The primary aim of this study was to test whether there was a difference between patients with MS (Group 1) and the control group (Group 2, patients with psoriasis and myasthenia gravis, diseases not affecting the central nervous system) in terms of the prevalence and types of primary headache. Materials and methods: A total of 139 patients with MS and 59 patients in the control group were included. The patients underwent a complete neurological examination and functional systems were assessed according to the functional system scores of Kurtzke. A semistructured interview guided by a questionnaire about headache was applied. Results: We found the life-long prevalence of primary headaches as 74.8% in patients with MS and as 71.2% in the control group. The prevalence of migraine and tension-type headaches did not show a significant difference between the 2 groups before the disease (P = 0.43), after the onset of disease (P = 0.18), or during the attack (P = 0.097). Conclusion: MS does not increase the prevalence of headaches, and headache types do not show any difference between MS patients and the control group.

🔖

Cite This Article

SORGUN, M. H., YÜCESAN, C., GENÇ, Y. (2013). Headache in multiple sclerosis. Turkish Journal of Medical Sciences, Cilt: 43 - Sayı: 6, 1042–1049. https://ajindex.com/articles/398181

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Kister I, Caminero AB, Monteith TS, Soliman A, Bacon TE, Bacon JH, Kalina JT, Inglese M, Herbert J, Lipton RB. Migraine is comorbid with multiple sclerosis and associated with a more symptomatic MS course. J Headache Pain 2010; 11: 417–425. Editorial. Headache in multiple sclerosis. Brit Med J 1969; 1: 713–714.
  2. Villani V, Prosperini L, Ciuffoli A, Pizzolato R, Savletti M, Sette G. Primary headache and multiple sclerosis: preliminary results of prospective study. Neurol Sci 2008; 29: 146–148.
  3. Sandyk R, Awerbuch GI. The co-occurrence of multiple sclerosis and migraine headache: the serotoninergic link. Int J Neurosci 1994; 76: 249–257.
  4. Haas DC, Kent PF, Friedman DI. Headache caused by a single lesion of multiple sclerosis in the periaqueductal gray area. Headache 1993; 33: 452–455.
  5. Rolak LA, Brown S. Headaches and multiple sclerosis: a clinical study and review of the literature. Neurology 1990; 237: 300– 302. Gee JR, Chang J, Dubli AB, Vijayan N. The association of brainstem lesions with migraine-like headache: an imaging study of multiple sclerosis. Headache 2005; 45: 670–677.
  6. Galer BS, Lipton RB, Weinstein S, Bello L, Solomon S. Apoplectic headache and oculomotor palsy: an unusual presentation of multiple sclerosis. Neurology 1990; 40: 1465– 1466. Leandri M, Cruccu G, Gottlieb A. Cluster headache-like pain in multiple sclerosis. Cephalagia 1999; 19: 732–734.
  7. Gentille S, Ferrero M, Vaula G, Rainero I, Pinessi L. Cluster headache attacks and multiple sclerosis. J Headache Pain 2007; 8: 245–247.
  8. Alstadhaug K, Breivik K, Rusic Z. Recurrent headache due to MS plaque. Headache 2008; 48: 453–454.
  9. Fragoso YD, Brooks JB. Two cases of lesions in brainstem in multiple sclerosis and refractory migraine. Headache 2007; 47: 852–854.
  10. Liu FC, Fuh JL, Wang SJ. Symptomatic trigeminal autonomic cephalalgia associated with allodynia in a patient with multiple sclerosis. J Chin Med Assoc 2008; 71: 583–586.
  11. Polmann W, Erasmus LP, Feneberg W, Bergh FT, Straube A. Interferon beta but not glatiramer acetate therapy aggravates headaches in MS. Neurology 2002; 24: 605–607.
  12. Boneschi FM, Colombo B, Annovazzi P, Martinelli V, Bernasconi L, Solaro C, Comi G. Lifetime and actual prevalence of any type of pain and headache in multiple sclerosis. Mult Scler 2008; 14: 514–521.
  13. La Mantia L, D’Amico D, Rigamonti A, Mascoli N, Bussone G, Milanese C. Interferon treatment may trigger primary headaches in multiple sclerosis patients. Mult Scler 2006; 12: 476–480. Headache Classification Subcommi