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Journals / Türk Geriatri Dergisi / 2012 / Cilt: 15 - Sayı: 3

Osteoporosıs, subclınıcal vertebral fractures and related factors ın patıents wıth perıpheral arterıal dısease

Periferik arter hastalığı olan kişilerde osteoporoz, subklinik vertebral kırık varlığı ve etkileyen faktörler

Banu DİLEK
Ebru ŞAHİN
Özalp KARABAY
Metin MANİSALI
Sema ÖNCEL
Meltem BAYDAR
Seide Alev KARASEL
Belgin ÜNAL
Pages
249–254
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

On the other hand,subclinical vertebral fractures significant- ly correlated with the stage of the disease and the weakness symptom(p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Introduction: The aim of the present study is to investigate the factors,affecting osteoporo- sis and subclinical vertebral fracture in patients with peripheral arterial disease(PAD).
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Key Findings & Data:Materials and Method: Eighty patients over 45 years of age with a diagnosis of PAD and without a history of osteoporosis were included in the study.The patients were queried in terms of demographic characteristics,calcium intake and physical activity.BMD was measured by a dual energy X-ray absorbsiometer(DEXA).The loss of vertebral height was determined.PAD was staged according to Fontaine’s classification.Serum calcium,phosphorus,alkaline phosphatase, 25(OH)D,parathormone,homocysteine and B12 levels were measured and thyroid,renal and hepatic function tests were performed.
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Conclusion & Impact:On the other hand,subclinical vertebral fractures significant- ly correlated with the stage of the disease and the weakness symptom(p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Introduction: The aim of the present study is to investigate the factors,affecting osteoporo- sis and subclinical vertebral fracture in patients with peripheral arterial disease(PAD). Materials and Method: Eighty patients over 45 years of age with a diagnosis of PAD and without a history of osteoporosis were included in the study.The patients were queried in terms of demographic characteristics,calcium intake and physical activity.BMD was measured by a dual energy X-ray absorbsiometer(DEXA).The loss of vertebral height was determined.PAD was staged according to Fontaine’s classification.Serum calcium,phosphorus,alkaline phosphatase, 25(OH)D,parathormone,homocysteine and B12 levels were measured and thyroid,renal and hepatic function tests were performed. Results: According to the DEXA measurements,19.17% (14)of the patients had osteoporo- sis while 63.01%(46) of them had osteopenia.Of the patients 28(36.70%)and 8(10.12%)had grade 1 and grade 2 vertebral fractures, respectively.Radiologically confirmed vertebral fractures were not present in 43(53.2%) patients.No significant relation was found between the stage of the PAD, BMD and t scores (p>0.05). On the other hand,subclinical vertebral fractures significant- ly correlated with the stage of the disease and the weakness symptom(p

Özet

Giriş: Bu çalışmanın amacı,periferik arter hastalığı olan hastalarda osteoporoz, subklinik vertebral kırık varlığı ve kemik mineral yoğunluğuna(KMY)etki eden faktörlerin araştırılmasıdır.Gereç ve Yöntem: Çalışmaya periferik arter hastalığı(PAH) tanısı almış,bilinen osteoporozu olmayan 45 yaş üzeri 80 hasta alındı.Hastaların demografik özellikleri, kalsiyum alımı ve fiziksel aktivite düzeyleri sorgulandı.Hastaların KMY Dual energy X-Ray Absorbsiometri(DEXA) ile ölçüldü. Vertebra yükseklik kayıpları değerlendirildi. PAH derecelendirmesi ise Fontaine sınıflamasına göre yapıldı. Ayrıca hastaların serumda kalsiyum, fosfor, alkalen fosfataz, 25(OH) D vitamin, parathormon, homosistein, B12 düzeyleri, tiroid, böbrek ve karaciğer fonksiyon testleri ölçüldü.Bulgular: DEXA ölçümlerine göre %19,17(14) hastada osteoporoz, %63,01(46) hastada osteopeni saptandı. Vertebral kırık derecesine bakıldığında 28( %36,70)'inda evre 1, 8(%10,12)'inde evre 2 kırık saptanırken 43(%53,2)'ünde radyolojik kırık saptanmadı. PAH evresi ile KMY ve t skorları arasında istatistiksel olarak anlamlı bir ilişki saptanmadı (p>0.05 ). Subklinik vertebral kırık ile hastalığın evresi ve güçsüzlük semptomu arasında istatistiksel olarak anlamlı ilişki saptandı (p

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Cite This Article

DİLEK, B., ŞAHİN, E., KARABAY, Ö., MANİSALI, M., ÖNCEL, S., BAYDAR, M., KARASEL, S. A., ÜNAL, B. (2022). Osteoporosıs, subclınıcal vertebral fractures and related factors ın patıents wıth perıpheral arterıal dısease. Türk Geriatri Dergisi, Cilt: 15 - Sayı: 3, 249–254. https://ajindex.com/articles/624254

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