NON-TRADITIONAL MORTALITY PREDICTORS FOR GERIATRIC INTENSIVE CARE UNIT PATIENTS

Objective & Hypothesis:Introduction: There is an increased number of elderly patients in intensive care units.Decreased physiological reserve and frailty makes them more vulnerable to illnesses.Materials and Method: Geriatric intensive care unit patients (n=1093), who had nohistory of malignancy and chemotherapy with hospitalised more than 3 days were examinedretrospectively.

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Key Findings & Data:Clinical and laboratory values on admission and at the final, discharge or dead,were recorded.

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Conclusion & Impact:In addition timely changed NLR and MPV were also independent mortality predictors[0.41 (95% CI 0.30-0.55) p

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Domain Parameters

Abstract

Introduction: There is an increased number of elderly patients in intensive care units.Decreased physiological reserve and frailty makes them more vulnerable to illnesses.Materials and Method: Geriatric intensive care unit patients (n=1093), who had nohistory of malignancy and chemotherapy with hospitalised more than 3 days were examinedretrospectively. Clinical and laboratory values on admission and at the final, discharge or dead,were recorded. Non traditional mortality predictors neutrophil,to,lymphocyte count (NLR) andmean platelet volume (MPV), and timely changes of these parameters were examined.Results: Readily measurable and effective markers foreseeing outcome are vitalimportance. In this retrospective cohort, we showed that neutrophil-to-lymphocyte count(NLR) and mean platelet volume (MPV) are independent mortality predictors in geriatricpatients. In addition timely changed NLR and MPV were also independent mortality predictors[0.41 (95% CI 0.30-0.55) p

Özet

Giriş: Yoğun bakımlarda izlenen geriatrik hasta sayısı giderek artmaktadır. Fizyolojik rezervlerin azalması ve kırılganlık, bu hastaları, daha savunmasız hale getirmektedir. Prognozu öngörmede, kolay ölçülebilen ve etkili göstergeler hayati önem taşımaktadır. Gereç ve Yöntem: Bu çalışmada, yoğun bakım ünitesinde 3 günden fazla yatarak izlenen, herhangi bir malignite ve kemoterapi öyküsü olmayan geriatrik hastaların (n=1093) verileri retrospektif olarak incelenmiştir. Hastaların laboratuvar ve klinik verileri, kliniğe giriş ve sonlanım olmak üzere kaydedildi. Geleneksel olmayan mortalite öngörücüleri; nötrofil-lenfosit oranı (NLO) ve ortalama trombosit hacmi (MPV) ve bu parametrelerin zamansal değişimi incelenmiştir. Retrospektif kohort çalışmamızda, geriatrik hastalarda nötrofil-lenfosit oranı (NLO) ve ortalama trombosit hacminin (MPV) bağımsız mortalite prediktörleri olduğunu saptadık. Aynı zamanda, NLO ve MPV’nin zamanla değişiminin de mortalite göstergesi olduğunu saptadık [sırasıyla 0.41 (% 95CI 0.30-0.55) p

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Cite This Article

KILAVUZ, A., AKÇİÇEK, F., BOZKURT, D., KÖSE, T., CAFEROV, N. (2022). NON-TRADITIONAL MORTALITY PREDICTORS FOR GERIATRIC INTENSIVE CARE UNIT PATIENTS. Türk Geriatri Dergisi, Cilt: 21 - Sayı: 3, 323–332. https://ajindex.com/articles/623694

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