AI Summary & Key Takeaways
AI InsightThe Child-Turcotte-Pugh classification andModel of End-Stage Liver Disease scoring should be undertaken, and thesuitability for liver transplantation should be considered in the follow-up andtreatment of this patients
📌 3 Key Takeaways
Abstract
Objective: Since there is insufficient epidemiological data on liver cirrhosis,especially in the elderly population of many countries, we aimed to evaluategeriatric cases with liver cirrhosis hospitalized at our gastroenterology clinic,retrospectively.Materials and Methods: The study included 99 patients aged 65 years and overwho were hospitalized with liver cirrhosis in Ege University Faculty of Medicine,department of gastroenterology. The socio-demographic, clinical and laboratorydata were recorded from the patient files.Results: In total, 99 elderly patients (mean age 71.7 ± 5.2 years; 59% male) wereincluded. Hepatocellular carcinoma was statistically significantly correlated withetiology, presence of ascites, the Model of End-Stage Liver Disease score and theChild-Turcotte-Pugh score (p=0.003, p=0.009, p=0.033, p=0.003, respectively).The presence of esophageal varices was statistically significantly correlated withclass and scores of the Child-Turcotte-Pugh, total bilirubin, Model of End-StageLiver Disease score and the presence of ascites (p< 0.0001, p=0.001, p=0.011,p=0.004, p=0.004, respectively).Conclusion: The main etiology of liver cirrhosis was Hepatitis C virus, whichaccounted for almost one-third of the cirrhotic elderly inpatients at thegastroenterology department. Hepatocellular carsinoma was the leading cause ofhospitalization. Elderly patients with liver cirrhosis should be carefullyevaluated for cirrhosis complications. The Child-Turcotte-Pugh classification andModel of End-Stage Liver Disease scoring should be undertaken, and thesuitability for liver transplantation should be considered in the follow-up andtreatment of this patients
Özet
Amaç: Birçok ülkenin yaşlı popülasyonunda karaciğer sirozu hakkında yeterli epidemiyolojik veri olmadığı için gastroenteroloji kliniğimizde yatan karaciğer sirozu tanılı geriatrik olguların retrospektif olarak değerlendirilmesi amaçlandı. Gereç ve Yöntem: Çalışmaya Ege Üniversitesi Tıp Fakültesi Gastroenteroloji kliniğinde yatmış 65 yaş ve üzeri karaciğer sirozu tanılı 99 hasta dâhil edildi.Sosyodemografik, klinik ve laboratuvar verileri hasta dosyalarından kaydedilmiştir. Bulgular: Çalışmaya dahil edilen 99 yaşlı hastanın yaş ortalaması 71,7 ± 5,2 yıl, % 59’u erkek idi. Hepatoselüler karsinom ile etiyoloji, asit varlığı, Model of EndStage Liver Disease skoru ve Child-Turcotte-Pugh skoru arasında istatistiksel olarak anlamlı ilişki saptanmıştır (sırasıyla, p = 0,003, p = 0,009, p = 0,033, p = 0,003). Özofagus varisi varlığı ile Child-Turcotte-Pugh sınıfı ve skoru, total bilirubin, Model of End-Stage Liver Disease skoru ve asit varlığı arasında istatistiksel olarak anlamlı ilişki saptanmıştır (sırasıyla, p