Journals / Türk Geriatri Dergisi / 2019 / Cilt: 22 - Sayı: 4

THE PROGNOSTIC ROLE OF NEUTROPHILTO- LYMPHOCYTE AND PLATELET-TOLYMPHOCYTE RATIOS IN PATIENTS WITH ASPIRATION PNEUMONIA

ASPİRASYON PNÖMONİLİ HASTALARDA NÖTROFİL LENFOSİT ORANI VE PLATELET LENFOSİT ORANININ PROGNOZ İLE İLİŞKİSİ

Pages
400–408
Publication Date
2022-11-04
DOI
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TheNLR cutoff value was determined as 8, and sensitivity and specificity for admission to theICU was 68.25% and 58.89%, respectively (AUC, 0.62), whereas sensitivity and specificity formortality were 67.86% and 54.48%, respectively (AUC, 0.658).Conclusion: NLR has a prognostic value in predicting ICU admission and mortality inpatients with aspiration pneumonia.

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: Aspiration pneumonia is difficult to diagnose, and it has a high mortalityrate.
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Key Findings & Data:In this study, the prognostic values of neutrophil-to-lymphocyte ratio (NLR) and plateletto-lymphocyte ratio (PLR) and their association with intensive care unit (ICU) admission andmortality were investigated in patients with aspiration pneumonia.Materials and Method: Between November 2016 and December 2018, 162 patientsaged>40 years, with no immunosuppression or malignancy, and hospitalized with a diagnosisof aspiration pneumonia were included in this retrospective study.
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Conclusion & Impact:TheNLR cutoff value was determined as 8, and sensitivity and specificity for admission to theICU was 68.25% and 58.89%, respectively (AUC, 0.62), whereas sensitivity and specificity formortality were 67.86% and 54.48%, respectively (AUC, 0.658).Conclusion: NLR has a prognostic value in predicting ICU admission and mortality inpatients with aspiration pneumonia.
🔬Design:Research Article
📍Scope:2016 Verileri
⚙️Variables:Domain Parameters

Abstract

Introduction: Aspiration pneumonia is difficult to diagnose, and it has a high mortalityrate. In this study, the prognostic values of neutrophil-to-lymphocyte ratio (NLR) and plateletto-lymphocyte ratio (PLR) and their association with intensive care unit (ICU) admission andmortality were investigated in patients with aspiration pneumonia.Materials and Method: Between November 2016 and December 2018, 162 patientsaged>40 years, with no immunosuppression or malignancy, and hospitalized with a diagnosisof aspiration pneumonia were included in this retrospective study. The patients were dividedinto two groups: those with and without ICU admission. In addition, the patients were dividedinto two groups: those who died and recovered. NLR and PLR ratios were compared betweengroups.Results: Among the 162 patients, 87 (54%) were male and 75 (46%) were female, 72patients were administered to the ICU, and 28 died. NLRs in patients admitted to the ICU(13.88±10.83) compared with those who were not admitted (10.5±10.07) and NLRs in patientswho died (14.91±9.41) compared with those who recovered (11.4±10.67) were significantlyhigh (p0.05). TheNLR cutoff value was determined as 8, and sensitivity and specificity for admission to theICU was 68.25% and 58.89%, respectively (AUC, 0.62), whereas sensitivity and specificity formortality were 67.86% and 54.48%, respectively (AUC, 0.658).Conclusion: NLR has a prognostic value in predicting ICU admission and mortality inpatients with aspiration pneumonia.

Özet

Giriş: Aspirasyon pnömonisi, tanısı zor, mortalitesi yüksek bir hastalıktır. Bu çalışmada, aspirasyon pnömonili hastalarda, nötrofil lenfosit oranı (NLO) ve platelet lenfosit oranının (PLO), yoğun bakıma giriş ve mortalite ile ilişkili prognostik değerinin incelenmesi amaçlanmıştır. Gereç ve Yöntem: Kasım 2016-Aralık 2018 tarihleri arasında başvuran, 40 yaş üzerinde, immünsüpresyonu ve malignitesi olmayan, aspirasyon pnömonisi tanısı konularak hastaneye yatırılan 162 hasta retrospektif olarak çalışmaya alındı. Hastalar yoğun bakıma yatış ve ex olmalarına göre iki ayrı gruba ayrıldı, bu gruplarda NLO ve PLO oranları karşılaştırıldı. Bulgular: 162 hastanın 87’si (%54) erkek, 75’i (%46) kadındı. 72 hasta yoğun bakıma alınırken, 28 hasta öldü. NLO seviyeleri yoğun bakıma giren hastalarda (13.88±10.83), girmeyenlere (10.5±10.07) göre; ölen hastalarda (14.91±9.41), ölmeyenlere göre (11.4±10.67) istatistiksel olarak anlamlı yüksek saptandı (p0.05). NLO cut-off değeri 8 olarak saptanmış olup, yoğun bakıma giriş için sensitivite ve spesifitesi %68.25 ve %58,89 (AUC:0.62); mortalite için sensitivite ve spesifitesi %67.86 ve %54.48 saptandı (AUC:0,658). Sonuç: Aspirasyon pnömonisi hastaların, NLO’nın yoğun bakıma giriş ve mortaliteyi öngörmede prognostik değeri olduğu saptandı.

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Cite This Article

ÇALIŞKAN, T., AYTEN, Ö., CANOĞLU, K. (2022). THE PROGNOSTIC ROLE OF NEUTROPHILTO- LYMPHOCYTE AND PLATELET-TOLYMPHOCYTE RATIOS IN PATIENTS WITH ASPIRATION PNEUMONIA. Türk Geriatri Dergisi, Cilt: 22 - Sayı: 4, 400–408. https://ajindex.com/articles/623655

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