Subclinical peripheral neuropathy in Behcet’s disease

Objective & Hypothesis:Background and Design: Central nervous system involvement is well known in patients with Behcet’s disease but studies evaluating peripheral nervous system is not usual.

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Key Findings & Data:Material and Method: Thirty three Behcet’s disease patients (23 male, 10 women) with no evident neurological sign and symptom and 33 healthy volunteers were enrolled to the study.

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Conclusion & Impact:Control group were normal electrophysiologically and the difference was statistically important (p

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Domain Parameters

Abstract

Background and Design: Central nervous system involvement is well known in patients with Behcet’s disease but studies evaluating peripheral nervous system is not usual. The aim of this study is to evaluate the frequency and characteristics of subclinical neuropathy in patients with Behcet’s disease. Material and Method: Thirty three Behcet’s disease patients (23 male, 10 women) with no evident neurological sign and symptom and 33 healthy volunteers were enrolled to the study. To exclude the other causes of peripheral neuropathy, some laboratory investigations were made. Electrophysiological studies of peripheral nerves were performed to all patients and healthy volunteers. The results were assessed according to the American Diabetes Association Diabetic Neuropathy Protocol. Results: Nerve conduction studies were abnormal in 11 of 33 patients (7 men, 4 women; 33.3%). Five patients (15%) had sensorymotor polyneuropathy, 4 (12%) has sural sensory polyneuropathy, 1 (3%) had median and tibial motor neuropathy. Sural nerve were unobtainable in 7 (21%) patients. 2 patients (6%) had prolonged F latency. Control group were normal electrophysiologically and the difference was statistically important (p

Özet

Amaç: Behçet hastalarında santral sinir sistemi tutulumu iyi bilinmekle beraber periferik sinir sistemi tutulumu henüz netleşmemiştir. Bu çalışmanın amacı Behçet hastalarında elektrofizyolojik inceleme ile subklinik periferik nöropatinin sıklığını ve özelliklerini değerlendirmektir. Gereç ve Yöntem: Çalışmaya, nörolojik olarak semptom ve bulguları olmayan 33 Behçet hastası (23 erkek, 10 kadın) ile yaş ve cinsiyetleri uyumlu 33 sağlıklı gönüllü alındı. Periferik sinir işlevlerini etkileyebilecek diğer etkenleri saptamaya yönelik tetkikleri yapıldı. Çalışmaya katılan tüm hasta ve sağlıklı gönüllülere standart nörografik prosedürler kullanılarak elektrofizyolojik inceleme yapıldı. Sonuçlar Amerikan Diyabet Cemiyeti Diyabetik Nöropati protokolüne göre değerlendirildi. Bulgular: Sinir ileti çalışması 33 hastanın 11’inde (7 erkek, 4 kadın, %33,3) anormaldi. Beş (%15) hastada sensorimotor polinöropati, 4 (%12) hastada sural sensoriyel nöropati, 1 (%3) hastada median ve tibial motor nöropati mevcuttu. Yedi (%21) hastada sural sensöriyel sinir elde edilemedi ve geç F latansı 2 (%6) hastada mevcuttu. Kontrol grubu elektrofizyolojik olarak normaldi ve fark istatistiksel olarak anlamlıydı (p

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Cite This Article

YILMAZER, S., DUMAN, T., TURHANOĞLU, A., BALCI, D. D., OKUYUCU, E. E., YENİN, J. Z. (2022). Subclinical peripheral neuropathy in Behcet’s disease. Türkderm-Deri Hastalıkları ve Frengi Arşivi, Cilt: 43 - Sayı: 2, 61–64. https://ajindex.com/articles/622061

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