Journals / Türkderm-Deri Hastalıkları ve Frengi Arşivi / 2011 / Cilt: 45 - Sayı: 3

The role of biopsy in pediatric dermatopathology

Pediyatrik dermatopatolojide biyopsinin rolü

Pages
137–139
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

An easy biopsy procedure for thepatient, an effective designation of biopsy indication, a good dermatopathologic correlation and an experienced team of pediatric dermatopathology increase the success of skin biopsies. (Turk derm 2011; 45: 137-9)

📌 3 Key Takeaways

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Objective & Hypothesis:Background and Design: Pediatric dermatology is characterized by skin disorders which have frequencies different from those in adults.
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Key Findings & Data:Results: Two hundred thirteen (1.7%) skin biopsies had been taken from a total of 12420 patients.
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Conclusion & Impact:An easy biopsy procedure for thepatient, an effective designation of biopsy indication, a good dermatopathologic correlation and an experienced team of pediatric dermatopathology increase the success of skin biopsies. (Turk derm 2011; 45: 137-9)
🔬Design:Research Article
📍Scope:2011 Verileri
⚙️Variables:Domain Parameters

Abstract

Background and Design: Pediatric dermatology is characterized by skin disorders which have frequencies different from those in adults. Skin biopsies are necessary for differential diagnosis and clinicopathologic correlation is very important. The aim of this study was to evaluate retrospectively the pediatric dermatology cases in whom biopsy was performed for differential diagnosis and to investigate the contribution of biopsy to diagnosis of skin disorders.Material and Methods: The cases from whom biopsy was taken in the pediatric dermatology clinic during a three-year period were evaluated retrospectively for pre-diagnoses, biopsy diagnoses, and success of biopsies. Results: Two hundred thirteen (1.7%) skin biopsies had been taken from a total of 12420 patients. Henoch-Schönlein purpura,psoriasis, pityriasis lichenoides, pityriasis rosea, lichen planus, pityriasis rubra pilaris, erythema multiforme, atopic dermatitis,granuloma annulare, and pigmented purpuric dermatosis were the most frequent skin disorders diagnosed dermatopathologically. In a total of 120 (56.3%) cases, the biopsy diagnosis was within the pre-diagnosis and a biopsy consistency was present. In 25 (11.7%) cases, biopsy had no contribution to the differential diagnosis. An absolutely different diagnosis which was incompatible with the pre-diagnosis had been reported in 10 (4.6%) cases.Conclusion: In pediatric dermatology, skin biopsy is very helpful for the differential diagnosis. An easy biopsy procedure for thepatient, an effective designation of biopsy indication, a good dermatopathologic correlation and an experienced team of pediatric dermatopathology increase the success of skin biopsies. (Turk derm 2011; 45: 137-9)

Özet

Amaç: Pediyatrik dermatoloji erişkinler ile karşılaştırıldığında deri hastalıklarının farklı sıklıklarla görülmesi ile karakterizedir. Deri biyopsileri ayırıcı tanıda gereklidir ve klinikopatolojik korelasyon çok önemlidir. Bu çalışmanın amacı ayırıcı tanı için deri biyopsi- si alınan pediatrik dermatoloji olgularını retrospektif olarak değerlendirmek ve biyopsinin deri hastalıklarında tanıya katkısını irde- lemekti.Gereç ve Yöntem: Üç yıllık period boyunca pediyatrik dermatoloji kliniğinde biyopsi alınan olgular ön tanılar, biyopsi tanıları ve biyopsi başarısı açısından retrospektif olarak değerlendirildi. Bulgular: Toplam 12420 adet hastanın 213’üne (%1,7) biyopsi uygulanmıştı. Henoch-Schönlein purpurası, psoriasis, pityriasis likenoides, pitriyasis rosea, liken planus, pitriyasis rubra pilaris, eritema multiforme, atopik dermatit, granuloma anulare, pigmen- te purpurik dermatoz dermatopatolojik olarak en sık tanı konan deri hastalıkları idi. Toplam 120 (%56,3) olguda biyopsi tanısı ön tanılar içinde yer almakta olup, biyopsi uyumu mevcuttu. Yirmi beş (%11,7) olguda biyopsi ayırıcı tanıya katkı sağlamamıştı. On (%4,6) olguda ön tanılardan hiçbiri ile uymayan farklı kesin tanı rapor edildiği saptandı. Sonuç: Pediyatrik dermatolojide deri biyopsisi ayırıcı tanıya çok yardımcıdır. Hastaya kolaylık sağlayan bir biyopsi alma işlemi, biyopsi indikasyonunun etkin konulması, iyi bir dermatopatolojik korelasyon ve deneyimli bir pediyatrik dermatopatoloji ekibi ile deri biyopsilerinin başarısı artmaktadır. (Türk derm 2011; 45: 137-9)

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Cite This Article

DİNİZ, G., AKTAŞ, S., ORTAÇ, R., AFŞAR, F. Ş. (2022). The role of biopsy in pediatric dermatopathology. Türkderm-Deri Hastalıkları ve Frengi Arşivi, Cilt: 45 - Sayı: 3, 137–139. https://ajindex.com/articles/622002

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References (18)

  1. Tamer E, Ilhan MN, Polat M, Lenk N, Alli N: Prevalence of skin diseases among pediatric patients in Turkey. J Dermatol 2008;35:413-8
  2. Sardana K, Mahajan S, Sarkar R, Mendiratta V, Bhushan P, Koranne RV, et al: The spectrum of skin disease among Indian children. Pediatr Dermatol 2009;26:6-13
  3. Kutzner H, Kempf W, Schärer L, Requena L: Optimizing dermatopathologic diagnosis with digital photography and internet. The significance of clinicopathologic correlation. Hautarz 2007;58:760-8
  4. Sidbury R: What's new in pediatric dermatology: update for the pediatrician. Curr Opin Pediatr 2004;16:410-4
  5. Davin JC, Weening JJ: Diagnosis of Henoch-Schönlein purpura: renal or skin biopsy? Pediatr Nephrol 2003;18:1201-3
  6. González LM, Janniger CK, Schwartz RA: Pediatric Henoch-Schönlein purpura. Int J Dermatol 2009;48:1157-65
  7. Pirgon O, Atabek ME, Sert A: Psoriasis following growth hormone therapy in a child. Ann Pharmacother 2007;41:157-60
  8. Farber EM, Nall L: Childhood psoriasis. Cutis 1999;64:309-14
  9. Herbst RA, Hoch O, Kapp A, Weiss J: Guttate psoriasis triggered by perianal streptococcal dermatitis in a four-year-old boy. J Am Acad Dermatol 2000;42:885-7
  10. Cohen DM, Ben-Amitai D, Feinmesser M, Zvulunov A: Childhood lichen planus pemphigoides: a case report and review of the literature. Pediatr Dermatol 2009;26:569-74
  11. Handa S, Sahoo B. Childhood lichen planus: a study of 87 cases. Int J Dermatol 2002;41:423-7
  12. Woo V, Bonks J, Borukhova L, Zegarelli D: Oral lichenoid drug eruption: a report of a pediatric case and review of the literature. Pediatr Dermatol 2009;26:458-64
  13. Rogers M: Pityriasis lichenoides and lymphomatoid papulosis. Semin Dermatol 1992;11:73-9
  14. Longley J, Demar L, Feinstein RP, Miller RL, Silvers DN: Clinical and histologic features of pityriasis lichenoides et varioliformis acuta in children. Arch Dermatol 1987;123:1335-9
  15. Kerkar N, Cohen S, Dugan C, Morotti RA, Phelps RG, Herold B, et al: Bullous pemphigoid after liver transplantation for liver failure. Liver Transpl 2006;12:1705-10
  16. Sina B, Kao GF, Deng AC, Gaspari AA: Skin biopsy for inflammatory and common neoplastic skin diseases: optimum time, best location and preferred techniques. A critical review. J Cutan Pathol 2009;36:505-10
  17. Gilliam AE: Skin signs of systemic disease in childhood. Adv Dermatol 2006;22:1-30
  18. Salem OS, Maize JC: Clinicopathologic correlation in diagnosis of diseases of the skin. Am J Dermatopathol 1986;8:53-6