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Journals / Türk Biyokimya Dergisi / 2013 / Cilt: 38 - Sayı: 3

Effects of Ellagic acid and Hesperetin on Levels of Some Elements in Livers of Aluminum-Induced Rats

Aluminyuma Maruz Kalmış Sıçanların Karaciğerlerindeki Bazı Elementlerin Seviyeleri Üzerine Hesperetin ve Ellagik Asitin Etkileri

Harun ÇİFTÇİ
Ali ÖLÇÜCÜ
Alpaslan DAYANGAÇ
Ahmet OZKAYA
Sait ÇELİK
B Sitki ÇEVRİMLİ
Pages
345–349
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Determinations of iron, calcium, copper and zinc were performed using a Flame Atomic Absorption Spectrometer and determination of aluminum and manganese were carried out with Inductively Coupled Plasma Atomic Emission Spectrometer.Results: Levels of aluminum, calcium and iron in AlCl3 treated group were found to be increased compared to the control group (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Ellagic acid and hesperetin are well known as having free radical scavenging activity in some rat tissues.
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Key Findings & Data:In this study, the protective role of ellagic acid and hesperetin has been investigated on macro and trace elements in liver of rats treated with AlCl3.Method: Thirty-six healthy adult male Spraque-dawley rats (240±10 g body weight) were used in this study.
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Conclusion & Impact:Determinations of iron, calcium, copper and zinc were performed using a Flame Atomic Absorption Spectrometer and determination of aluminum and manganese were carried out with Inductively Coupled Plasma Atomic Emission Spectrometer.Results: Levels of aluminum, calcium and iron in AlCl3 treated group were found to be increased compared to the control group (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Ellagic acid and hesperetin are well known as having free radical scavenging activity in some rat tissues. Aluminum is known to cause toxic effects on various organ systems. In this study, the protective role of ellagic acid and hesperetin has been investigated on macro and trace elements in liver of rats treated with AlCl3.Method: Thirty-six healthy adult male Spraque-dawley rats (240±10 g body weight) were used in this study. The rats were randomly divided into six groups and Ellagic acid, Hesperetin, AlCl3, AlCl3+ Ellagic acid and AlCl3+Hesperetin were treated to each group except from the control group. Determinations of iron, calcium, copper and zinc were performed using a Flame Atomic Absorption Spectrometer and determination of aluminum and manganese were carried out with Inductively Coupled Plasma Atomic Emission Spectrometer.Results: Levels of aluminum, calcium and iron in AlCl3 treated group were found to be increased compared to the control group (p

Özet

Amaç: Ellagik asit ve hesperetinin bazı sıçan dokularında serbest radikal seviyelerini azaltıcı aktiviteye sahip oldukları iyi bilinmektedir. Alüminyumun çeşitli organ sistemleri üzerine toksik etkisinin olduğu bilinmektedir. Bu çalışmada AlCl3 uygulanmış sıçanların karaciğerlerinde makro ve eser elementlerin seviyeleri üzerine ellagik asit ve hesperetinin koruyucu etkileri araştırılmıştır.Yöntem: Bu çalışmada 36 adet sağlıklı erkek Spraque-dawley sıçanı (240±10 g ağırlığında) kullanılmıştır. Sıçanlar rastgele seçilerek 6 grup oluşturulmuş, bir grup kontrol grubu olarak kalmış, diğer grupların her birine Ellagik asit, Hesperetin, AlCl3, AlCl3+ Ellagik asit ve AlCl3+Hesperetin uygulanmıştır. Demir, kalsiyum, bakır ve çinko miktarları Alevli Atomik Absorbsiyon Spektrofotometresi ile aluminyum ve mangan miktarları ise indüklenmiş eşleşmiş plazma atomik emisyon spektrofotometresi ile tayin edilmiştir.Bulgular: AlCluygulanan grupta alüminyum, kalsiyum ve demir düzeylerinin kontrol grubuna göre arttığı gözlenmiştir (p

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Cite This Article

ÇİFTÇİ, H., ÖLÇÜCÜ, A., DAYANGAÇ, A., OZKAYA, A., ÇELİK, S., ÇEVRİMLİ, B. S. (2022). Effects of Ellagic acid and Hesperetin on Levels of Some Elements in Livers of Aluminum-Induced Rats. Türk Biyokimya Dergisi, Cilt: 38 - Sayı: 3, 345–349. https://ajindex.com/articles/621424

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