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Journals / Türk Biyokimya Dergisi / 2007 / Cilt: 32 - Sayı: 3

Fizyolojik sıvılardaki biyojen aminlerin metabolik döngüsü: Tanısal önemi

Metabolic turnover of biogenic amines in physiological fluids: Diagnostic significances

Emin SOFIC
Pages
120–129
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This review article holds the reference values and metabolic ratio of catecholamines, serotonin and their metabolites in the serum, cerebrospinal fluids and urine for healthy persons and values and metabolic ratio of catecholamines, serotonin and their metabolites in patients with phaeochromocytoma and carcinoids syndrome.

📌 3 Key Takeaways

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Objective & Hypothesis:The term of biogenic amine is an umbrella term that encompasses all amines with an origin in biological processes.
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Key Findings & Data:This review will be restricted to the biogenic amine abnormalities that affect the metabolism of the catecholamines and serotonin mostly in patients with phaeochromocytoma and carcinoid syndrome, and the inborn errors that primarily affect their metabolism.
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Conclusion & Impact:This review article holds the reference values and metabolic ratio of catecholamines, serotonin and their metabolites in the serum, cerebrospinal fluids and urine for healthy persons and values and metabolic ratio of catecholamines, serotonin and their metabolites in patients with phaeochromocytoma and carcinoids syndrome.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The term of biogenic amine is an umbrella term that encompasses all amines with an origin in biological processes. This review will be restricted to the biogenic amine abnormalities that affect the metabolism of the catecholamines and serotonin mostly in patients with phaeochromocytoma and carcinoid syndrome, and the inborn errors that primarily affect their metabolism. An idea is also developed that proposes that abnormalities of biogenic amine metabolism are far more common than is currently considered, and that the search for these problems may be appropriate in any neonate or children who presents with neurological problems of unknown origin. Correction of the abnormal neurochemical pattern could predict treatment efficacy. This review article holds the reference values and metabolic ratio of catecholamines, serotonin and their metabolites in the serum, cerebrospinal fluids and urine for healthy persons and values and metabolic ratio of catecholamines, serotonin and their metabolites in patients with phaeochromocytoma and carcinoids syndrome.

Özet

Biyolojik amin terimi kökeni biyolojik oluşumlar olan tüm aminleri kapsamaktadır. Bu derleme sadece çoğunlukla feokromositoma ve karsinoid sendrom hastaları ile doğuştan kaynaklanan serotonin ve katekolamin metabolizmasını etkileyen biyolojik amin anormalilerni ele almaktadır. Biyolojik amin metabolizması bozukluklarının tahmin edilenden daha fazla olduğu ve tüm yenidoğanlarda yada kökeni bilinmeyen nörolojik sorunlara sahip tüm çocuklarda bu metabolik bozukluğun araştırılması fikri önerilmektedir. Anormal nörokimyasal modelin düzeltilmesi tedavi etkinliğinin tahminine olanak sağlayabilir. Derleme, hem sağlıklı kişilerde hemde feokromositoma ve karsinoid sendrom hastalarında gözlenen katekolamin, serotonin ve metabolitlerinin serum, serebrospinal sıvı ve idrarda gözlenen referans değerlerini ve metabolik oranlarını içermektedir.

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Cite This Article

SOFIC, E. (2022). Fizyolojik sıvılardaki biyojen aminlerin metabolik döngüsü: Tanısal önemi. Türk Biyokimya Dergisi, Cilt: 32 - Sayı: 3, 120–129. https://ajindex.com/articles/621402

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