Journals / Türk Biyokimya Dergisi / 2008 / Cilt: 33 - Sayı: 1

Correlation of serum butyrylcholinesterase activity with preoperative anxiety and lipid levels

Serum bütirilkolinesteraz aktivitesinin ameliyat öncesi anksiyete ve lipit düzeyleriyle ilişkisi

Pages
9–13
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: Serum cholinesterase activity was significantly higher in patients who had an operation compared to the healthy control group (6191 ± 1396 and 5379 ± 1552 U/L; p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: The objective of this study was to determine the correlation between serum butyrylcholinesterase activity, preoperative anxiety and lipid profile in operated patients.
📊
Key Findings & Data:Methods: A total of 80 samples were studied.
💡
Conclusion & Impact:Results: Serum cholinesterase activity was significantly higher in patients who had an operation compared to the healthy control group (6191 ± 1396 and 5379 ± 1552 U/L; p
🔬Design:Research Article
📍Scope:80 samples
⚙️Variables:Domain Parameters

Abstract

Objective: The objective of this study was to determine the correlation between serum butyrylcholinesterase activity, preoperative anxiety and lipid profile in operated patients. Methods: A total of 80 samples were studied. Forty-seven of them were from operated patients and 33 of them were from healthy control volunteers. Fasting blood samples were drawn from patients one hour before the operation and before 11.00 a.m. from controls. Serum cholinesterase activity, triglycerides, total cholesterol, low density lipoprotein, cholesterol, alanine amino transferase and aspartate amino transferase activities were measured. Anxiety levels were assessed by using the hospital anxiety and depression scale of Beck anxiety inventory. Results: Serum cholinesterase activity was significantly higher in patients who had an operation compared to the healthy control group (6191 ± 1396 and 5379 ± 1552 U/L; p

Özet

Amaç: Bu çalışmanın amacı ameliyata alınacak hastalarda serum bütirilkolinesteraz aktivitesi ile ameliyat öncesi anksiyete ve lipit profili arasındaki ilişkiyi belirlemektir. Metot: Kırk yedisi ameliyat olacak hasta ve 32’si sağlıklı bireyler olmak üzere toplam 80 kişi üzerinde çalışıldı. Hastalardan ameliyattan 1 saat önce ve kontrol grubundan sabah açlık kan örnekleri alındı. Serum bütirilkolinesteraz aktivitesi, total kolesterol, trigliserit, düşük yoğunluklu lipoprotein, kolesterol, alanin amino transferaz ve aspartat amino transferaz düzeyleri ölçüldü. Anksiyete düzeyi hastane anksiyete ve depresyon skalası olan Beck Anksiyete Envanteri kullanılarak değerlendirildi. Bulgular: Serum bütirilkolinesteraz aktivitesi ameliyat edilen hasta grubunda kontrol grubuna göre anlamlı derecede yüksekti (6191 ± 1396 ve 5379 ± 1552 U/L; p

🔖

Cite This Article

YILMAZ, U., KUTSAL, C., AĞIRGÖL, B. A., İŞLETEN, F., SEMERCİ, E. (2022). Correlation of serum butyrylcholinesterase activity with preoperative anxiety and lipid levels. Türk Biyokimya Dergisi, Cilt: 33 - Sayı: 1, 9–13. https://ajindex.com/articles/621346

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (10)

  1. Milligan KR, Hayes TC, Huss BK, Beattie B. (1986) Atypical plasma cholinesterase. Anaesthesia. 41: 841-843
  2. Chatonnet A, Lockridge O. (1989) Comparision of butyrylcholinesterase and acetycholinesterase. Biochem J. 260: 625-634 [3] Ballantyne FC. (1968) Histocemical and biochemical aspects of cholinesterase activity of adipose tissue. Arch Int Pharmacodyn. 173: 348–9
  3. Graybiel AM, Ragsdale CW Jr. (1982) Pseudocholinesterase staining in the primary visual pathway of the macaque monkey. Nature. 299: 439–42
  4. Dave KR, Syal AR, Katyare SS. (2000) Tissue cholinesterases. A comparative study of their kinetic properties. Z Naturforsch. 55(1-2): 100-8 [6] Darvesh S, Hopkins DA, Geula C. (2003) Neurobiology of butyrylcholinesterase.Nat Rev Neurosci. 4: 131-8
  5. Calderon-Margalit R, Adler B, Abramson JH, Gofin J, Kark JD. (2006) Butyrylcholinestarase activity, cardiovasculer risk factors and mortality in middle-aged and elderly men and women in. Jerusalem. Clin Chem. 52(5): 845-52
  6. Kutty KM, Annanpurna V, Prabhakaran V. (1989) Pseudocholinesterase: A protein with functions unrelated to its name. Biochem Soc Trans. 7: 555–6
  7. Kutty KM, Payne RH. (1994) Serum pseudocholinesterase and very–low–density lipoprotein metabolism. J Clin Lab Anal. 8:247–50
  8. Barta C, Sasvari-Szekely M, Devai A, Kovacs E, Staub M, Enyedi P. (2001) Analysis of mutations in the plasma cholinesterase gene of patients with a history of prolonged neuromuscular block during anesthesia. Mol Genet Metab. 74: 484-8
  9. Scheinin M, Scheinin H, Ekbland U, Kanto J. (1990) Biological correlates of mental stress related to anticipated caesarean section. Acta Anaesthesiol Scand. 34: 640-644 [12] Modai I, Mendelsohn E, Schwartz B. (1987) Serum cholinesterase in state anxiety. J Clin Psychiatry. 48: 204-206 [13] Mathew RJ, Hsu LL, Semchuk KM, Claghorn JL. (1980) Acetylcholinesterase and pseudocholinesterase activities in anxiety. Am J Psychiatry. 137(9): 1118-20
  10. Zigmond AS, Snaith RP. (1983) The hospital anxiety and depression scale. Acta Psychiatry Scand. 67: 361-370 [15] Schulz-Stubner S, de Bruin J, Neuser J, Rossaint R. (2001) Validation of an observer-based rating set compared to a standardized written psychological test for the diagnosis of depression and anxiety in a university preadmission test center. Anaesthesiol Intensivmed Noftallmed Schmertzther. 36: 331-335 [16] Davies P, Landy M. (1998) Suxamethonium and mivacurium sensitivity from pregnancy-induced plasma cho