Journals / Türk Biyokimya Dergisi / 2009 / Cilt: 34 - Sayı: 4

Küçük hücreli dışı akciğer kanserinde doku oksidatif stresi

Tissue oxidative stress in non small cell lung cancer

Pages
215–219
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However, vitamin Econtents of the malignant tissues were significantly higher than the normal tissues(p

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: As the leading cause of adult mortality for many countries, lung cancer wasconsidered to be related with free radical injury.
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Key Findings & Data:We aimed to investigate if the oxidative stress is increased or not in malignant tissues, compared to the normal onesin non small cell lung cancer.
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Conclusion & Impact:However, vitamin Econtents of the malignant tissues were significantly higher than the normal tissues(p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: As the leading cause of adult mortality for many countries, lung cancer wasconsidered to be related with free radical injury. We aimed to investigate if the oxidative stress is increased or not in malignant tissues, compared to the normal onesin non small cell lung cancer. Methods: We compared malignant and normal lung tissues for their malondialdehyde, total thiol and vitamin E contents in 35 smoker patients with non small celllung cancer. Results: There was no significant difference between malignant and normal tissuesfor malondialdehyde and total thiol concentrations (p>0.05). However, vitamin Econtents of the malignant tissues were significantly higher than the normal tissues(p

Özet

Amaç: Birçok ülkede erişkin ölümlerinin en sık nedeni olan akciğer kanserininserbest radikal hasarı ile ilişkili olduğu düşünülmektedir. Çalışmamızda oksidatifstresin küçük hücreli dışı akciğer kanserli dokuda normal dokuya göre artıp artmadığını araştırmayı amaçladık. Metod: Küçük hücreli dışı akciğer kanseri olan 35 sigara içicisi hastanın malign venormal akciğer dokuları malondialdehit, toplam tiyol ve vitamin E içerikleri açısından karşılaştırıldı. Bulgular: Malondialdehit ve toplam tiyol konsantrasyonu açısından malign ve normal akciğer dokuları arasında anlamlı fark yoktu (p>0.05). Bununla birlikte vitamin E konsantrasyonları malign dokularda normal dokulara göre belirgin yüksekti (p

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Cite This Article

YÜCEL, D., BERKOĞLU, M., KIYICI, A., BERKTAŞ, B. M., AYDIN, L. Y. (2022). Küçük hücreli dışı akciğer kanserinde doku oksidatif stresi. Türk Biyokimya Dergisi, Cilt: 34 - Sayı: 4, 215–219. https://ajindex.com/articles/621335

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References (1)

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