Journals / Türk Biyokimya Dergisi / 2013 / Cilt: 38 - Sayı: 1

Sigara kullanımının hematolojik parametrelere etkisi: Sigara kullanan erkekler ile kullanmayan bireylerin karşılaştırılması

Effect of cigarette smoking based on hematological DEDE parameters: comparison between male smokers and non- smokers

Pages
75–80
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: In conclusion, our findings showed that continuous cigarette smoking has severe adverse affects on hematological parameters (e.g., hemoglobin, hematocrit, WBC count, RBC count, and platelet crit) and these alterations might be associated with a greater risk for developing atherosclerosis, polycythemia vera, chronic obstructive pulmonary disease and/or cardiovascular diseases

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The effects of cigarette smoking on human health are serious and in many cases, deadly.
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Key Findings & Data:Subjects and Method: One hundred and forty two male subjects participated in this study: smokers (n=71) and nonsmokers (n=71).
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Conclusion & Impact:Conclusion: In conclusion, our findings showed that continuous cigarette smoking has severe adverse affects on hematological parameters (e.g., hemoglobin, hematocrit, WBC count, RBC count, and platelet crit) and these alterations might be associated with a greater risk for developing atherosclerosis, polycythemia vera, chronic obstructive pulmonary disease and/or cardiovascular diseases
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The effects of cigarette smoking on human health are serious and in many cases, deadly. The aim of the present study was to assess the extent of adverse effects of cigarette smoking on biochemical characteristics of blood in male population of Quetta city in Pakistan. Subjects and Method: One hundred and forty two male subjects participated in this study: smokers (n=71) and nonsmokers (n=71). The smokers were regularly consuming 11-20 cigarettes per day for at least 3 years. Complete blood cell count were measured by Nihon Codon fully automatic Hematological analyzer.Results: The smokers had significantly higher levels of white blood cell (p< 0.027), red blood cell (p< 0.011), hemoglobin (p< 0.001) and hematocrit (p< 0.006), whereas mean corpuscular hemoglobin concentration (p< 0.009) and platelet crit (p< 0.017) were significantly lower. Conclusion: In conclusion, our findings showed that continuous cigarette smoking has severe adverse affects on hematological parameters (e.g., hemoglobin, hematocrit, WBC count, RBC count, and platelet crit) and these alterations might be associated with a greater risk for developing atherosclerosis, polycythemia vera, chronic obstructive pulmonary disease and/or cardiovascular diseases

Özet

Amaç: Sigara kullanımının insan sağlığı üzerine olan etkisi ciddi boyutlardadır, hatta birçok durumda ölüme neden olmaktadır. Çalışmanın amacı Pakistan'ın Quetta şehrinde yaşayan erkeklerde sigara kullanımının kanın biyokimyasal özelliklerine olan yan etkilerinin araştırılmasıdır. Yöntem: Çalışmaya yüz kırk iki erkek birey katılmıştır: Sigara kullanan bireyler (n=71) ve sigara kullanmayan bireyler (n=71). Sigara içen bireyler en az 3 senedir düzenli olarak günde 11-20 sigara içen bireylerdir. Tam kan sayımı Nihon Codon tam otomatik hematolojik analizör ile yapılmıştır. Bulgular: Sigara içen bireylerde beyaz kan hücreleri (p< 0.027), kırmızı kan hücreleri (p< 0.011), hemoglobin (p< 0.001) ve hematokrit (p< 0.006) düzeyleri belirgin bir şekilde yüksek, ortalama korpusküler hemoglobin derşimi (p< 0.009) ve platelet crit (p< 0.017) ise düşük bulunmuştur.Sonuç: Çalışma bulguları sürekli sigara kullanımının hematolojik parametreler (hemoglobin, hematokrit, beyaz ve kırmızı kan hücrelerinin sayısı ve platelet crit vb.) üzerine ciddi yan etkilerinin olduğunu göstermektedir. Bu değişimler ateroskleroz, polisitemia vera, kronik obstrüktif akciğer hastalığı ve/vaya kardiyovasküler hastalıkların gelişimi ile ilişkili olabilir

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Cite This Article

ASİF, M., KARİM, S., UMAR, Z., ISMAİL, T., CHAUDHARY, A., ALQAHTANİ, M. H., RASOOL, M., MALİK, A. (2022). Sigara kullanımının hematolojik parametrelere etkisi: Sigara kullanan erkekler ile kullanmayan bireylerin karşılaştırılması. Türk Biyokimya Dergisi, Cilt: 38 - Sayı: 1, 75–80. https://ajindex.com/articles/621295

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