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Journals / Türk Biyokimya Dergisi / 2014 / Cilt: 39 - Sayı: 2

The evaluation of IMA as a cardiac ischemia marker in the cases of hypohemoglobinemia and hypoxemia due to blood loss

Kan kaybına bağlı hemoglobin düşüklüğü ve hipoksemi durumunda kardiak iskemi belirteci olarak İMA

Ali Kemal OĞUZ
Selda DEMİRTAŞ
Sedat ÖZDEMİR
Meltem AYLI
Konçuy MERGEN
Rabia ŞEKER
Pages
221–225
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Patients were divided into three sub-groups according to their hemoglobin levels (

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Although the mechanism is still not so clear, ischemia modified albumin is produced as a result of the occurrence of changes in metal binding regions on the albumin with the production of reactive oxygen species.
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Key Findings & Data:This study is designed to investigate the correlation between hypohemoglobinemia, hypoxemia due to blood loss and IMA.Methods: The research is carried out with 83 patients (28 Male, 55 Female; mean age: 51±22 year) and 19 subject as control group (7Male, 12 Female; mean age 35±18 year).
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Conclusion & Impact:Patients were divided into three sub-groups according to their hemoglobin levels (
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Although the mechanism is still not so clear, ischemia modified albumin is produced as a result of the occurrence of changes in metal binding regions on the albumin with the production of reactive oxygen species. But it is not known whether this change is the cause or the result of different states. This study is designed to investigate the correlation between hypohemoglobinemia, hypoxemia due to blood loss and IMA.Methods: The research is carried out with 83 patients (28 Male, 55 Female; mean age: 51±22 year) and 19 subject as control group (7Male, 12 Female; mean age 35±18 year). Patients were divided into three sub-groups according to their hemoglobin levels (

Özet

Amaç: Mekanizması hala net olmamakla birlikte iskemi modifiye albüminin (İMA); reaktif oksijen ürünlerinin üretimi ile albüminin metal bağlama bölgelerinde değişim meydana gelmesi sonucu oluştuğu düşünülmektedir. Fakat bu değişimin farklı durumların nedeni mi yoksa sonucu mu olduğu bilinmemektedir. Çalışmamız; kan kaybına bağlı hemoglobin düşüklüğü, hipoksemi ve İMA düzeyleri arasındaki korelasyonun değerlendirilmesi amacı ile planlanmıştır. Yöntemler: Araştırma 83 hasta (28E, 55K; ort. yaş: 51±22 yıl) ve 19 kontrol olgusu (7 E, 12K ort yaş: 35±18 yıl) üzerinde yapılmıştır. Hasta grubumuz hemoglobin düzeylerine göre 3 alt gruba ayrılmıştır (

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Cite This Article

OĞUZ, A. K., DEMİRTAŞ, S., ÖZDEMİR, S., AYLI, M., MERGEN, K., ŞEKER, R. (2022). The evaluation of IMA as a cardiac ischemia marker in the cases of hypohemoglobinemia and hypoxemia due to blood loss. Türk Biyokimya Dergisi, Cilt: 39 - Sayı: 2, 221–225. https://ajindex.com/articles/621214

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