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Journals / Türk Biyokimya Dergisi / 2015 / Cilt: 40 - Sayı: 3

Referans aralık hesaplamada alt grup belirleme yöntemi ve bir uygulama

Determination of sub-groups in reference interval calculations and an application

Gülhan Orekici TEMEL
E Arzu KANIK
Didem Derici YİLDİRİM
H Didem OVLA
Hakan KALAFAT
Pages
197–204
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Harris&Boyd method was used for sex and age while the MARS method was used for the determination of age sub-groups.Results: According to the Harris&Boyd method, it was concluded that it is not necessary to create sub-groups for sex and age variables.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The main objective of this study is to determine the methods used for dividing reference data into sub-groups and propose a new solution.
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Key Findings & Data:MARS 2.0 package software was used for the statistical analysis.
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Conclusion & Impact:Harris&Boyd method was used for sex and age while the MARS method was used for the determination of age sub-groups.Results: According to the Harris&Boyd method, it was concluded that it is not necessary to create sub-groups for sex and age variables.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The main objective of this study is to determine the methods used for dividing reference data into sub-groups and propose a new solution. Therefore, the newly proposed method is used to determine age sub-groups while calculating the reference interval of AST variable.Methods: The data of this study are composed of the registered patients who applied only once to the polyclinics at the Health Research and Application Hospital, Clinical Bio-Chemistry Laboratory of Mersin University. The main variables selected for the study are sex, age and aspartate transaminase (AST). MARS 2.0 package software was used for the statistical analysis. Harris&Boyd method was used for sex and age while the MARS method was used for the determination of age sub-groups.Results: According to the Harris&Boyd method, it was concluded that it is not necessary to create sub-groups for sex and age variables. Age sub-groups are determined with the MARS method by taking into account the correlations between AST variables and age. Age sub-groups are calculated as 5-9, 10-18 and 19+. Correlation between the age and AST variable is investigated for these sub-groups. It is obtained that the correlation is statistically not significant for the 5-9 age group (p=0.3189), significant for the 10-18 age group (p

Özet

Amaç: Bu çalışmanın amacı referans verilerini alt gruplara ayırmada kullanılan yöntemleri belirlemek ve yeni bir yöntem önermektir. Bu amaçla yeni önerilen yöntem, AST değişkeninin referans aralığı hesaplanırken yaş alt gruplarının belirlenebilmesi amacı ile kullanılmıştır.Metod: Çalışmaya ait veriler, Mersin Üniversitesi Sağlık Araştırma ve Uygulama Hastanesi Klinik Biyokimya Laboratuvarında sadece bir kez polikliniğe başvuran hastaların kayıtlı verileri ile oluşturulmuştur. Bu çalışmada seçilen değişkenler cinsiyet, yaş ve aspartat transaminaz (AST)'dır. İstatistik analizlerde MARS 2.0 paket programı kullanılmıştır. Harris&Boyd yöntemi cinsiyet ve yaş, MARS yöntemi yaş alt grubunun belirlenmesinde kullanılmıştır.Bulgular: Harris&Boyd yöntemine göre cinsiyet ve yaş değişkeninde ayırmanın yapılmasına gerek olmadığı sonucu çıkmıştır. AST değişkeni ile yaş arasındaki ilişkilere bakılarak MARS yöntemi ile yaş alt grupları belirlendi. Yaş alt grupları 5-9; 10-18 ve 19 ve üzeri olarak hesaplandı. Bu alt gruplardaki yaş ile AST değişkeni arasındaki ilişkilere bakıldı. 5-9 yaş grubunda ilişki anlamsız (p=0.3189), 10-18 yaş grubunda ilişki anlamlı (p

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Cite This Article

TEMEL, G. O., KANIK, E. A., YİLDİRİM, D. D., OVLA, H. D., KALAFAT, H. (2022). Referans aralık hesaplamada alt grup belirleme yöntemi ve bir uygulama. Türk Biyokimya Dergisi, Cilt: 40 - Sayı: 3, 197–204. https://ajindex.com/articles/621145

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