Journals / Türk Biyokimya Dergisi / 2016 / Cilt: 41 - Sayı: 4

Akut böbrek hasarının nadir bir nedeni: Hipotiroidizm

A rare cause of acute kidney injury: hypothyroidism

Pages
288–291
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Hypothyroidism should not be overlooked as the cause of reversible kidney injury since it is easy to treat, and there is almost complete response to treatment in terms of renal failure

📌 3 Key Takeaways

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Objective & Hypothesis:Kidneys and thyroid are two basic organs that interact with each other, and when one of them becomes ill, functions of the other are affected.
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Key Findings & Data:We reported a 75-year-old female patient who admitted for acute kidney injury associated with deep hypothyroidism, required hemodialysis, and underwent a renal biopsy since no etiological factors were detected for acute kidney injury.
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Conclusion & Impact:Hypothyroidism should not be overlooked as the cause of reversible kidney injury since it is easy to treat, and there is almost complete response to treatment in terms of renal failure
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Kidneys and thyroid are two basic organs that interact with each other, and when one of them becomes ill, functions of the other are affected. Although electrolyte disturbances are the most common symptoms reported due to hypothyroidism, some are case reports in the literature suggested that acute kidney injury developed due to hypothyroidism. Despite this, we doubt that this information comes into mind in routine clinical practice. To report a case of reversible hypothyroidism-induced acute kidney injury, and review those two clinical conditions, which are often overlooked in the nephrology practice, in the light of the literature. We reported a 75-year-old female patient who admitted for acute kidney injury associated with deep hypothyroidism, required hemodialysis, and underwent a renal biopsy since no etiological factors were detected for acute kidney injury. We emphasized that the patient’s creatinine concentrations gradually returned to normal following hormone replacement therapy. Renal dysfunction in presence of hypothyroidism is a known, but frequently overlooked entity. Hypothyroidism should not be overlooked as the cause of reversible kidney injury since it is easy to treat, and there is almost complete response to treatment in terms of renal failure

Özet

Böbrek ve tiroid, birbirleri ile etkileşim içinde olan, birinin hastalığı varlığında diğerinin fonksiyonlarında değişikliklerin izlendiği iki temel organdır. Hipotiroidizm zemininde bildirilen en sık bulgu elektrolit bozuklukları olmakla birlikte, hipotiroidizm zemininde gelişen akut böbrek hasarı vaka bildirileri literatürde yer almaktadır. Buna rağmen hipotiroidizm ve böbrek yetmezliği birlikteliği klinik pratiğe girmiş bir bilgi değildir. Hipotiroidizmin neden olduğu akut böbrek hasarı vakasını sunmak ve literatürde yer alan ancak nefroloji pratiğinde etyolojide sıklıkla gözden kaçan bu iki klinik durumu literatür eşli- ğinde incelemek. Biz burada, derin hipotiroidizme bağlı akut böbrek hasarı ile gelen ve hemodiyaliz ihtiyacı olan, etyolojide neden saptanamaması üzerine böbrek biyopsisi yapılan, tiroid hormon replasmanı sonrası kreatinin değerleri tedricen gerileyen 75 yaşındaki bayan hastayı sunduk. Hipotiroidizm varlığında renal disfonksiyon sıklıkla gözlenebilen klinik birlikteliklerden olup tedavisinin kolay ve yanıtın tama yakın olmasından dolayı reversibl böbrek hasarının gözden kaçmaması gereken nedenlerindendir.

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Cite This Article

CEVHER, Ş. K., YENİGÜN, E. Ç., ÖZTÜRK, R., DEDE, F. (2022). Akut böbrek hasarının nadir bir nedeni: Hipotiroidizm. Türk Biyokimya Dergisi, Cilt: 41 - Sayı: 4, 288–291. https://ajindex.com/articles/621077

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