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Journals / Türk Biyokimya Dergisi / 2019 / Cilt: 44 - Sayı: 5

The importance of parathormone in determining the deficiency of vitamin D

Parathormonun D vitamini eksikliğinin belirlenmesindeki önemi

Cahit KAÇAR
Sebahat ÖZDEM
Sevcan UĞUR
Pages
585–593
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The minimum 25-OH vitamin D level to keep PTH below 65 pg/mL was18.5 ng/mL.Conclusion: For determining the threshold value of 25 OH vitamin D, serum PTH levels should be assessed with 25-OH vitamin D levels

📌 3 Key Takeaways

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Objective & Hypothesis:Background: To evaluate the association of parathormone with vitamin D and to find a threshold value for vitamin D.Material and methods: This descriptive study included 11,753 (2352 males, 9401 females) patients from University hospital and 25-OH vitamin D and PTH levels wereevaluated.Results: The mean parathormone level was 49.33 ± 22.39 pg/mL. 18.7% of the patients had hyperparathyroidism. 77.4% of the patients had low 25-OH D vitamins.
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Key Findings & Data:Therewas a negative correlation between serum parathormone levels and 25-OH vitamin D levels.
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Conclusion & Impact:The minimum 25-OH vitamin D level to keep PTH below 65 pg/mL was18.5 ng/mL.Conclusion: For determining the threshold value of 25 OH vitamin D, serum PTH levels should be assessed with 25-OH vitamin D levels
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background: To evaluate the association of parathormone with vitamin D and to find a threshold value for vitamin D.Material and methods: This descriptive study included 11,753 (2352 males, 9401 females) patients from University hospital and 25-OH vitamin D and PTH levels wereevaluated.Results: The mean parathormone level was 49.33 ± 22.39 pg/mL. 18.7% of the patients had hyperparathyroidism. 77.4% of the patients had low 25-OH D vitamins. Therewas a negative correlation between serum parathormone levels and 25-OH vitamin D levels. The minimum 25-OH vitamin D level to keep PTH below 65 pg/mL was18.5 ng/mL.Conclusion: For determining the threshold value of 25 OH vitamin D, serum PTH levels should be assessed with 25-OH vitamin D levels

Özet

ÖzAmaç: Çalışmamızda, parathormonun [PTH] 25 OH vitamin D ile ilişkisini değerlendirmek ve 25 OH vitamin D için eşik değeri bulmak amaçlandı.Gereç ve Yöntem: Bu tanımlayıcı çalışmada 11,753 (2352 erkek, 9401 kadın) hastanın 25 OH vitamin D ve PTH düzeyleri değerlendirildi.Bulgular: Parathormon ortalama değeri 49.33 ± 22.39 pg/mL idi. Hastaların % 18.7’sinde hiperparatiroidi vardı. Hastaların %77.4’ünde 25 OH vitamin D düşüktü. Serum parathormon düzeyleri ile 25 OH vitamin D düzeyleri arasında negatif korelasyon bulundu. PTH’ı 65 pg/mL’nin altında tutmak için gerekli minimum 25 OH vitamin D seviyesi 18.5 ng/mL bulundu.Sonuç: 25 OH vitamin D eşik değerini belirlemek için serum PTH düzeyleri 25 OH vitamin D seviyeleri ile birlikte değerlendirilmelidir

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Cite This Article

KAÇAR, C., ÖZDEM, S., UĞUR, S. (2022). The importance of parathormone in determining the deficiency of vitamin D. Türk Biyokimya Dergisi, Cilt: 44 - Sayı: 5, 585–593. https://ajindex.com/articles/620866

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