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Journals / Türk Biyokimya Dergisi / 2020 / Cilt: 45 - Sayı: 3

Effect of iodine-containing antisepticson urine iodine levels of surgical staff afteriodization

İyodizasyon sonrası, iyot içeren antiseptiklerin cerrahi personelin idrar iyot düzeylerine etkisi

Sema YARMAN
İsmail Cem SORMAZ
Cemile IDİZ
Aysu ALTUN
Zuhal KOFOĞLU
Canan BAŞARAN KÜÇÜKGERGİN
Pages
277–281
Publication Date
2022-11-06
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Modified microplate method of Sandell-Kolthoff reaction used to measure UIC.Results: The UICs were significantly higher on Friday (median 194 μg/L (70–396 μg/L)) compared to the Monday concentrations (median 125 μg/L (62–264 μg/L), p 300 μg/L, but on Friday, 7.5% of the subjects had UIC > 300 μg/L.Conclusion: Despite both the use of iodized antiseptic solution and mandatory iodization, operation-room staff had only median iodine levels with low risk of iodine intoxication.

📌 3 Key Takeaways

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Objective & Hypothesis:Background: The routine use of topical iodinated antiseptic could be a possible cause of iodine contamination.
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Key Findings & Data:This study was aimed to determine urinary iodine status of operation-room staff who routinely use iodinecontaining antiseptics for cleansing of the hands after salt iodization.Materials and methods: The study included 40 operation-room staff who use surgical hand-scrub solutions.
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Conclusion & Impact:Modified microplate method of Sandell-Kolthoff reaction used to measure UIC.Results: The UICs were significantly higher on Friday (median 194 μg/L (70–396 μg/L)) compared to the Monday concentrations (median 125 μg/L (62–264 μg/L), p 300 μg/L, but on Friday, 7.5% of the subjects had UIC > 300 μg/L.Conclusion: Despite both the use of iodized antiseptic solution and mandatory iodization, operation-room staff had only median iodine levels with low risk of iodine intoxication.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background: The routine use of topical iodinated antiseptic could be a possible cause of iodine contamination. This study was aimed to determine urinary iodine status of operation-room staff who routinely use iodinecontaining antiseptics for cleansing of the hands after salt iodization.Materials and methods: The study included 40 operation-room staff who use surgical hand-scrub solutions. Participants applied an iodized brush for a minimum of three times a day on weekdays and were iodine-free on the weekends. Morning urine samples from all volunteers to analyze the urinary iodine concentration (UIC) twice a week. Modified microplate method of Sandell-Kolthoff reaction used to measure UIC.Results: The UICs were significantly higher on Friday (median 194 μg/L (70–396 μg/L)) compared to the Monday concentrations (median 125 μg/L (62–264 μg/L), p 300 μg/L, but on Friday, 7.5% of the subjects had UIC > 300 μg/L.Conclusion: Despite both the use of iodized antiseptic solution and mandatory iodization, operation-room staff had only median iodine levels with low risk of iodine intoxication.

Özet

to analyze the urinary iodine concentration (UIC) twicea week. Modified microplate method of Sandell-Kolthoffreaction used to measure UIC. Results: The UICs were significantly higher on Friday(median 194 μg/L (70–396 μg/L)) compared to the Mondayconcentrations (median 125 μg/L (62–264 μg/L), p 300 μg/L, but on Friday, 7.5% of thesubjects had UIC > 300 μg/L. Conclusion: Despite both the use of iodized antisepticsolution and mandatory iodization, operation-room staffhad only median iodine levels with low risk of iodineintoxication. Keywords: Surgery; Povidone-iodine; Hand disinfection;Urine; Turkey. Öz Amaç: Topikal iyotlu antiseptiklerin rutin kullanımı, iyotkontaminasyonunun olası bir nedeni olabilir. Bu çalış mada, tuzların iyodizasyonu sonrasında, el temizliğiiçin rutin olarak iyot içeren antiseptik kullanan ameli yathane personelinin idrar iyot durumunun belirlenmesiamaçlanmıştır. Gereç ve Yöntem: Çalışmaya cerrahi el yıkama solüsyon ları kullanan 40 ameliyathane personeli dahil edilmiştir.Katılımcılar, hafta içinde günde en az üç kez iyotlu fırçaile uygulama yapmış ve hafta sonları iyotlu solüsyon kul lanmamışlardır. İdrar iyot konsantrasyonunu (UIC) analizetmek için tüm gönüllülerden haftada iki kez sabah idrarörnekleri alınmıştır. İdrar iyot konsantrasyonunu ölçmekiçin Sandell-Kolthoff reaksiyonunun modifiye mikroplakametodu kullanılmıştır. Bulgular: Cuma günü saptanan UIC’ ler (medyan 194 μg/L(70–396 μg/L)), pazartesi günü konsantrasyonlarınagöre (medyan 125 μg/L (62–264 μg/L), p 300 μg/Lolmazken, cuma günü deneklerin %7,5′ inde UIC > 300μg/L’ dir. Sonuç: İyotlu antiseptik solüsyonların kullanımına vezorunlu iyodizasyona rağmen, ameliyathane personelininyalnızca medyan iyot seviyelerine sahip olduğu ve iyotintoksikasyonu riskinin düşük olduğu saptanmıştır.

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Cite This Article

YARMAN, S., SORMAZ, İ. C., IDİZ, C., ALTUN, A., KOFOĞLU, Z., KÜÇÜKGERGİN, C. B. (2022). Effect of iodine-containing antisepticson urine iodine levels of surgical staff afteriodization. Türk Biyokimya Dergisi, Cilt: 45 - Sayı: 3, 277–281. https://ajindex.com/articles/620787

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