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Journals / Türk Biyokimya Dergisi / 2020 / Cilt: 45 - Sayı: 6

Association between breast milk adipokines with growth in breast feeding infants, a systematic review and meta-analysis

[Anne sütü adipokinleri ile emziren bebeklerde büyüme Arasındaki İlişki, sistematik bir İnceleme ve meta-analiz]

Younes MOHAMMADİ
Mohammad Taghi GOODARZİ
Maryam SOORİ
Minoo MAHMOODİ
Pages
659–669
Publication Date
2022-11-06
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Theadiponectin level in breast milk was associated with theBMI and weight gain of infants.Conclusions: Meta-analysis indicated a significant inversecorrelation between breastmilk leptin with weight gain andBMI in infants; furthermore, the systematic review studyexpressed significant correlation between breast milkadiponectin with growth (BMI and weight gain) in infants.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: Breast milk adipokines are associated withgrowth, body mass index (BMI) and weight gain in infants.In this study, the effect of breastmilk adipokines (leptinand adiponectin) on the BMI and weight gain of breast-fedinfants was evaluated using systematic review and metaanalysis.Materials and methods: We used PRISMA checklist forcarrying out this study. 752 articles were collected from thedatabase searching and other sources from 1994 to April2019.
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Key Findings & Data:According to the criteria in the study, 25 articlesremained for evaluation.
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Conclusion & Impact:Theadiponectin level in breast milk was associated with theBMI and weight gain of infants.Conclusions: Meta-analysis indicated a significant inversecorrelation between breastmilk leptin with weight gain andBMI in infants; furthermore, the systematic review studyexpressed significant correlation between breast milkadiponectin with growth (BMI and weight gain) in infants.
🔬Design:Survey & Empirical Study
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: Breast milk adipokines are associated withgrowth, body mass index (BMI) and weight gain in infants.In this study, the effect of breastmilk adipokines (leptinand adiponectin) on the BMI and weight gain of breast-fedinfants was evaluated using systematic review and metaanalysis.Materials and methods: We used PRISMA checklist forcarrying out this study. 752 articles were collected from thedatabase searching and other sources from 1994 to April2019. According to the criteria in the study, 25 articlesremained for evaluation. Eight papers were related to theeffect of breast milk leptin on weight gain and BMI of infantsthat were evaluated by meta-analyzing. The adiponectinarticles were surveyed by systematic review.Results: There was no significant publication bias in themeta-analysis study. The results of random-effect modelindicated a reverse and significant correlation betweenbreastmilk leptin with weight gain and BMI (r=−0.331). Theadiponectin level in breast milk was associated with theBMI and weight gain of infants.Conclusions: Meta-analysis indicated a significant inversecorrelation between breastmilk leptin with weight gain andBMI in infants; furthermore, the systematic review studyexpressed significant correlation between breast milkadiponectin with growth (BMI and weight gain) in infants.

Özet

Amaç: Anne sütü adipokinleri bebeklerde büyüme, vücut kitle indeksi (VKİ) ve kilo alımı ile ilişkilidir. Bu çalışmada anne sütü adipokinlerinin (leptin ve adiponektin) anne sütüyle beslenen bebeklerin vücut kitle indeksi ve kilo alımı üzerindeki etkisi sistematik derleme ve meta-analiz kullanılarak değerlendirildi. Gereç ve Yöntemler: Bu çalışmayı gerçekleştirmek için PRISMA kontrol listesini kullandık. Veri tabanı taramasından ve diğer kaynaklardan 1994’ten Nisan 2019’a kadar 752 makale toplanmıştır. Çalışmadaki kriterlere göre değerlendirilmek üzere yirmi beş makale kalmıştır. Metaanaliz ile değerlendirilen sekiz makale, anne sütü leptininin bebeklerin kilo alımı ve BMI üzerindeki etkisi ile ilgilidir. Adiponektin makaleleri sistematik bir inceleme ile incelenmiştir. Bulgular: Meta-analiz çalışmasında önemli bir yayın yanlılığı yoktu. Rastgele etki modelinin sonuçları, anne sütü leptini ile kilo alımı ve VKİ arasında ters ve anlamlı bir korelasyon olduğunu gösterdi (r=−0.331). Anne sütündeki adiponektin düzeyi, bebeklerin vücut kitle indeksi ve kilo alımı ile ilişkiliydi. Sonuç: Meta-analiz bebeklerde anne sütü leptini ile kilo alımı ve VKİ arasında anlamlı bir ters ilişki olduğunu gösterdi; ayrıca, sistematik gözden geçirme çalışması bebeklerde anne sütü adiponektini ile büyüme (VKİ ve kilo artışı) arasında önemli bir korelasyon olduğunu ortaya koymuştur.

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Cite This Article

MOHAMMADİ, Y., GOODARZİ, M. T., SOORİ, M., MAHMOODİ, M. (2022). Association between breast milk adipokines with growth in breast feeding infants, a systematic review and meta-analysis. Türk Biyokimya Dergisi, Cilt: 45 - Sayı: 6, 659–669. https://ajindex.com/articles/620761

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References (13)

  1. Bell S, Yew S, Devenish G, Ha D, Do L, Scott J, et al. Duration of breastfeeding, but not timing of solid food, reduces the risk of overweight and obesity in children aged 24 to 36 months: findings from an Australian cohort study. Int J Environ Res Publ Health 2018;15:599
  2. Boquien C-Y. Human milk: an ideal food for nutrition of preterm newborn. J Front Pediatr 2018;6. https://doi.org/10.3389/fped. 2018.00295
  3. Woo JG, Guerrero ML, Guo F, Martin LJ, Davidson BS, Ortega H, et al. Human milk adiponectin impacts infant weight trajectory during the second year of life. J Pediatr Gastroenterol Nutr 2012; 54:532
  4. Larnkjær A, Ong KK, Carlsen EM, Ejlerskov KT, Mølgaard C, Michaelsen KF. The influence of maternal obesity and breastfeeding on infant appetite-and growth-related hormone concentrations: the SKOT cohort studies. J Horm Res Pediatr 2018;90:28–38
  5. Cesur G, Ozguner F, Yilmaz N, Bumin D. The relationship between ghrelin and adiponectin levels in breast milk and infant serum and growth of infants during early postnatal life. J Physiol Sci 2012;62:185–90
  6. Savino F, Lupica M, Benetti S, Petrucci E, Liguori SA, Di Montezemolo LC. Adiponectin in breast milk: relation to serum adiponectin concentration in lactating mothers and their infants. J Acta Paediatr 2012;101:1058–62
  7. Gridneva Z, Kugananthan S, Rea A, Lai C, Ward L, Murray K, et al. Human milk adiponectin and leptin and infant body composition over the first 12 months of lactation. J Nutrients 2018;10:1125
  8. Woo JG, Guerrero ML, Altaye M, Ruiz-Palacios GM, Martin LJ, Dubert-Ferrandon A, et al. Human milk adiponectin is associated with infant growth in two independent cohorts. J Breastfeed Med 2009;4:101–9
  9. Weyermann M, Brenner H, Rothenbacher DJE. Adipokines in human milk and risk of overweight in early childhood: a prospective cohort study. J Epidemiol 2007;18:722–9
  10. Savino F, FissoreMF, Liguori SA, Oggero R. Can hormones contained in mothers’ milk account for the beneficial effect of breast‐feeding on obesity in children?. J Clin Endocrinol 2009;71:757–65
  11. Kotani Y, Yokota I, Kitamura S, Matsuda J, Naito E, Kuroda Y. Plasma adiponectin levels in newborns are higher than those in adults and positively correlated with birth weight. J Clin Endocrinol 2004;61:418–23
  12. Doneray H, Orbak Z, Yildiz L. The relationship between breast milk leptin and neonatal weight gain. J Acta Paediatr 2009;98: 643–7
  13. Miralles O, Sánchez J, Palou A, Picó C. A physiological role of breast mi