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Journals / Türk Biyokimya Dergisi / 2021 / Cilt: 46 - Sayı: 4

An important source of preanalytical error in medical laboratories: centrifugation

Esin AVCI
Aylin HAKLIGÖR
Fatma TANELİ
Alper GÜMÜŞ
Ayfer ÇOLAK
Cihan COŞKUN
Çiğdem SÖNMEZ
Mehmet ŞENES
Fehime AKSUNGAR
Canan YILMAZ
Berrin Bercik İNAL
İpek ÇINAROĞLU
Pınar EKER
Funda GÜÇEL
Güzin AYKAL
Bagnu ORHAN
Pages
399–405
Publication Date
2022-11-06
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The purpose of this document is to ensure the standardization of a good, precise protocol for the centrifugation process among the medical laboratories.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Abstract: Centrifugation separates particles within the specimen according to their shape, dimensions, and density and basically can be defined as a separation method.
📊
Key Findings & Data:An accurate and precise centrifugation process is essential to prevent errors in the preanalytical phase.
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Conclusion & Impact:The purpose of this document is to ensure the standardization of a good, precise protocol for the centrifugation process among the medical laboratories.
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Abstract: Centrifugation separates particles within the specimen according to their shape, dimensions, and density and basically can be defined as a separation method. The centrifuge is an essential device in medical laboratories to prepare the serum, plasma, and urine samples for analysis. It is basically an electric device composed of the stationary (motor) and the motile (rotor) part. The centrifugation depends on two main variables: relative centrifugal force (RCF) and centrifugation time. The physical impact separating the specimen into its components in the centrifuge known as RCF is expressed as the multiples of gravitational acceleration (×g). RPM, defined as the number of rotations of the centrifuge perminute, shows the speed of the centrifuge. RCF value can be calculated by using RPM, and the centrifuge radius. Because models and sizes of centrifuges vary considerably, the use of gravity (g) forces instead of RPM is suggested. The centrifuges can be classified according to their usage, speed, technical specifications, and rotor type. An accurate and precise centrifugation process is essential to prevent errors in the preanalytical phase. The purpose of this document is to ensure the standardization of a good, precise protocol for the centrifugation process among the medical laboratories.

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Cite This Article

AVCI, E., HAKLIGÖR, A., TANELİ, F., GÜMÜŞ, A., ÇOLAK, A., COŞKUN, C., SÖNMEZ, Ç., ŞENES, M., AKSUNGAR, F., YILMAZ, C., İNAL, B. B., ÇINAROĞLU, İ., EKER, P., GÜÇEL, F., AYKAL, G., ORHAN, B. (2022). An important source of preanalytical error in medical laboratories: centrifugation. Türk Biyokimya Dergisi, Cilt: 46 - Sayı: 4, 399–405. https://ajindex.com/articles/620706

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