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Journals / Türk Biyokimya Dergisi / 2021 / Cilt: 46 - Sayı: 4

Comparison of biochemical and immunological biomarker levels of patients with COVID-19 with healthy individuals

Semra TUNÇBİLEK
Ayşe BİLGİHAN
Mehmet Emin TEKELİ
Cantürk KAYA
Emel TÜRK ARIBAŞ
Uğur ERÇİN
Aylin SEPİCİ DİNÇEL
Pages
367–375
Publication Date
2022-11-06
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Results: AAT, AGP, Total IgG, Gal3, and SARS-CoV-2 IgG levels were found to be significantly higher in the patient group compared to the control group (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: It was aimed to compare Alpha-1 antitrypsin (AAT), Alpha-1 acid glycoprotein (AGP), Total Immuno globulin M (Total IgM), Total Immunoglobulin G (Total IgG), Galectin-3 (Gal3), and severe acute respiratory syn drome coronavirus 2 IgG (SARS-CoV-2 IgG) levels in pa tients with COVID-19 and healthy individuals.
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Key Findings & Data:Methods: The study included a total of 86 participants, 44 patients diagnosed with COVID-19 by real-time reverse transcription-polymerase chain reaction (rRT-PCR) test and 42 as the control group.
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Conclusion & Impact:Results: AAT, AGP, Total IgG, Gal3, and SARS-CoV-2 IgG levels were found to be significantly higher in the patient group compared to the control group (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: It was aimed to compare Alpha-1 antitrypsin (AAT), Alpha-1 acid glycoprotein (AGP), Total Immuno globulin M (Total IgM), Total Immunoglobulin G (Total IgG), Galectin-3 (Gal3), and severe acute respiratory syn drome coronavirus 2 IgG (SARS-CoV-2 IgG) levels in pa tients with COVID-19 and healthy individuals. Methods: The study included a total of 86 participants, 44 patients diagnosed with COVID-19 by real-time reverse transcription-polymerase chain reaction (rRT-PCR) test and 42 as the control group. AAT, AGP, Total IgM, and Total IgG levels were measured using the immunoturbidimetric method. Gal3 and SARS-CoV-2 IgG levels were measured using the chemiluminescent microparticle immunoassay method. Results: AAT, AGP, Total IgG, Gal3, and SARS-CoV-2 IgG levels were found to be significantly higher in the patient group compared to the control group (p

Özet

Amaç: COVID-19’lu hastalarda Alfa-1 antitripsin (AAT), Alfa-1 asit glikoprotein (AGP), Total IgM, Total IgG, Galektin-3 (Gal3) ve SARS-CoV-2 IgG düzeylerini çalışarak sağlıklı bireylerle karşılaştırmak amaçlandı. Gereç ve Yöntem: Gerçek zamanlı ters transkripsiyon polimeraz zincir reaksiyonu (rRT-PCR) test sonucu ile COVID-19 tanısı alan 44’ü hasta, 42’si kontrol grubunu oluş turacak şekilde toplam 86 katılımcı çalışmaya dahil edildi. AAT, AGP, Total IgM ve Total IgG düzeyleri İmmüntürbidi metrik yöntem ile çalışıldı. Gal3 ve SARS-CoV-2 IgG düzeyleri ise kemilüminesan mikropartikül immünassay yöntemi ile ölçüldü. Bulgular: Hasta grubunda AAT, AGP, Total IgG, Gal3 ve SARS-CoV-2 IgG düzeyleri kontrol grubuna göre anlamlı derecede yüksek bulundu (tüm testler için p

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Cite This Article

TUNÇBİLEK, S., BİLGİHAN, A., TEKELİ, M. E., KAYA, C., ARIBAŞ, E. T., ERÇİN, U., DİNÇEL, A. S. (2022). Comparison of biochemical and immunological biomarker levels of patients with COVID-19 with healthy individuals. Türk Biyokimya Dergisi, Cilt: 46 - Sayı: 4, 367–375. https://ajindex.com/articles/620699

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