Journals / Türk Biyokimya Dergisi / 2021 / Cilt: 46 - Sayı: 5

The effects of vitamin D, fish oil and exercise on cardiovascular parameters in ovariectomized rats

Overiyektomize sıçanlarda vitamin D, balık yağı ve egzersizin kardiyovasküler parametreler üzerine etkileri

Pages
517–523
Publication Date
2022-11-06
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In analyzing the data, ANOVA and Tamhane’s T2 tests were used (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objectives: This study compared effects of vitamin D, fish oil and exercise on cardiovascular parameters in ova- riectomized rats.
📊
Key Findings & Data:Materials and methods: This is an experimental study conducted with 45 female Wistar Albino rats; consisted of one sham (n=8) and four intervention (n=37) groups.
💡
Conclusion & Impact:In analyzing the data, ANOVA and Tamhane’s T2 tests were used (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: This study compared effects of vitamin D, fish oil and exercise on cardiovascular parameters in ova- riectomized rats. Materials and methods: This is an experimental study conducted with 45 female Wistar Albino rats; consisted of one sham (n=8) and four intervention (n=37) groups. Rats (n=37) were oophorectomized and, randomly divided into four groups at the end of the first week following wound healing. Interventions were applied to the groups of oop- horectomize+Dvit, oophorectomize+fish oil and oopho- rectomize+exercise for 12 weeks. In analyzing the data, ANOVA and Tamhane’s T2 tests were used (p

Özet

Amaç: Bu çalışma, ooforektomize sıçanlarda vitamin D, balık yağı ve egzersizin kardiyovasküler parametreler üze- rine etkilerini karşılaştırdı. Gereç ve Yöntem: Bu, 215-257 gr ağırlığındaki 45 dişi Wistar Albino sıçanla yapılan deneysel bir çalışmadır ve bir sham (n=8) ve dört müdahale (n=37) grubundan oluşmaktadır. Müdahale grubundaki sıçanlar (n=37) ooforektomize edildi ve yara iyileşmesini takiben ilk hafta sonunda rastgele dört gruba ayrıldı. Daha sonra; ooforektomize+Dvit, ooforekto- mize+balık yağı ve ooferektomize+egzersiz gruplarına 12 hafta boyunca müdahaleler uygulandı. Verilerin analizinde ANOVA ve Tamhane T2 testleri kullanıldı (p

🔖

Cite This Article

Demirci, B., Hazar, F., Karul, A. B., Hazar, H. U. (2022). The effects of vitamin D, fish oil and exercise on cardiovascular parameters in ovariectomized rats. Türk Biyokimya Dergisi, Cilt: 46 - Sayı: 5, 517–523. https://ajindex.com/articles/620684

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (1)

  1. . World Health Organization (WHO). Cardiovascular diseases (CVDs). https://www.who.int/en/news-room/fact-sheets/ detail/cardiovascular-diseases-(cvds) (Last accessed: January 2021). 2. Cho L, Davis M, Elgendy I, Epps K, Lindley KJ, Mehta PK, et al. ACC CVD Womens Committee Members. Summary of updated recommendations for primary prevention of cardiovascular disease in women: JACC State of the Art Review. J Am Coll Cardiol 2020;75:2602–18. 3. WHO CVD Risk Chart Working Group. World Health Organization cardiovascular disease risk charts: revised models to estimate risk in 21 global regions. Lancet Glob Health 2019;7:e1332–45. 4. Banks E, Welsh J, Joshy G, Martin M, Paige E, Korda RJ. Comparison of cardiovascular disease risk factors, assessment and management in men and women, including consideration of absolute risk: a nationally representative cross-sectional study. BMJ Open 2020;10:e038761 5. Feldman RD. Heart disease in women: unappreciated challenges, GPER as a new target. Int J Mol Sci 2016;17:760. 6. Arnal JF, Fontaine C, Billon-Gal ́es A, Favre J, Laurell H, Lenfan F, et al. Estrogen receptors and endothelium. Arterioscler Thromb Vasc Biol 2010;30:1506–12. 7. Manson JE, Bassuk SS, Lee I, Cook NR, Albert MA, Gordon D, et al. The vitamin D and omega-3 trial (VITAL): rationale and design of a large randomized controlled trial of vitamin D and marine omega- 3 fatty acid supplements for the primary prevention of cancer and cardiovascular disease. Contemp Clin Trials 2012;33:159–71. 8. Rupp H, Rupp TP, Alter P, Maisch B. Mechanisms involved in the differential reduction of omega-3 and omega-6 highly unsaturated fatty acids by structural heart disease resulting in “HUFA deficiency”. Can J Physiol Pharmacol 2012;90:55–73. 9. Ferguson JF, Mulvey CK, Patel PN, Shah RY, Doveikis J, Zhang W, et al. Omega-3 PUFA supplementation and the response to evoked endotoxemia in healthy volunteers. Mol Nutr Food Res 2013;5:1–13. 10. Mosca L, Navar AM, Wenger NK. Reducing cardiovascular disease risk in women beyond statin therapy: new insights 2020. J Wom Health 2020;29:1091–100. 11. Hendrix J, Nijs J, Ickmans K, Godderis L, Ghosh M, Polli A. The interplay between oxidative stress, exercise, and pain in health and disease: potential role of autonomic regulation and epigenetic mechanisms. Antioxidants 2020;9:1166. 12. Sánchez-Rodríguez MA, Mendoza-Núñez VM. Oxidative stress indexes for diagnosis of health or disease in humans. Oxid Med Cell Longev 2019;2019:4128152. 13. Moham