The activities of LDH and LDH isoenzymes in the discrimination among tuberculous pleuritis, nonspecific pleuritis, congestive heart failure, pulmonary embolism were investigated.73 patients were included in the study.The activity of pleural fluid LD$H_1$ and LD$H_3$ isoenzymes in pulmonary embolism, LD$H_3$ and LD$H_5$ isoenzymes in the tuberculous pleuritis and LD$H_5$ izoenzyme in malign pleural effusions were found significantly high (p
📌 3 Key Takeaways
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Objective & Hypothesis:The activities of LDH and LDH isoenzymes in the discrimination among tuberculous pleuritis, nonspecific pleuritis, congestive heart failure, pulmonary embolism were investigated.73 patients were included in the study.The activity of pleural fluid LD$H_1$ and LD$H_3$ isoenzymes in pulmonary embolism, LD$H_3$ and LD$H_5$ isoenzymes in the tuberculous pleuritis and LD$H_5$ izoenzyme in malign pleural effusions were found significantly high (p
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Key Findings & Data:The activities of LDH and LDH isoenzymes in the discrimination among tuberculous pleuritis, nonspecific pleuritis, congestive heart failure, pulmonary embolism were investigated.73 patients were included in the study.The activity of pleural fluid LD$H_1$ and LD$H_3$ isoenzymes in pulmonary embolism, LD$H_3$ and LD$H_5$ isoenzymes in the tuberculous pleuritis and LD$H_5$ izoenzyme in malign pleural effusions were found significantly high (p
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Conclusion & Impact:The activities of LDH and LDH isoenzymes in the discrimination among tuberculous pleuritis, nonspecific pleuritis, congestive heart failure, pulmonary embolism were investigated.73 patients were included in the study.The activity of pleural fluid LD$H_1$ and LD$H_3$ isoenzymes in pulmonary embolism, LD$H_3$ and LD$H_5$ isoenzymes in the tuberculous pleuritis and LD$H_5$ izoenzyme in malign pleural effusions were found significantly high (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Abstract
The activities of LDH and LDH isoenzymes in the discrimination among tuberculous pleuritis, nonspecific pleuritis, congestive heart failure, pulmonary embolism were investigated.73 patients were included in the study.The activity of pleural fluid LD$H_1$ and LD$H_3$ isoenzymes in pulmonary embolism, LD$H_3$ and LD$H_5$ isoenzymes in the tuberculous pleuritis and LD$H_5$ izoenzyme in malign pleural effusions were found significantly high (p
Özet
Tüberküloz plörezi, parapnömonik efüzyon, konjestif kalp yetmezliği, pulmoner emboli, malign plevral efüzyon grupları arasındaki ayrımda, plevral sıvı LDH ve LDH izoenzimlerinin aktiviteleri incelendi.Çalışmaya 73 hasta alındı.LDH ve LDH izoenzimleri, plevral sıvıda ve serumda eş zamanlı bakılarak sonuçlar karşılaştırıldı.Pelvral sıvıda LD$H_3$ ve LD$H_5$ izoenzimleri tüberkülöz plörezide, LD$H_5$ izoenzimleri malign plevral efüzyonlarda anlamlı olarak yüksek bulundu (p< 0.05).LD$H_2$ vd LD$H_4$ izoenzimlerinin aktivitesinde gruplar arasında anlamlı farklılıklar bulunamadı.
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Cite This Article
ALPAR, S., KILINÇ, C., ALTUĞ, N., GÜLER, M., BİLGİN, M. G. (2022). The role of pleural fluid lactic acid dehydrogenase (LDH) isoenzymes in descriptive diagnosis. Tüberküloz ve Toraks, Cilt: 50 - Sayı: 1, 19–23. https://ajindex.com/articles/619329
Vladutiu AO. Approach to pleural effusions, in: Vladutiu AO (ed). Pleural Effusions. New York: Mount Kisco, 1986: 1-62
Bartter T, Akers SM. The evaluation of pleural effusion. Chest 1994; 106: 1209-14
Vergnon JM, Guidollet J. LDH isoenzyme electrophoretic patterns in the diagnosis of pleural effusion. Cancer 1984;54:507-ll
Izidore SL, Breuer R. Differential diagnosis of pleural effusion by LDH analysis. Chest 1997; 111: 648-51
Dev D, Joseph J. Pleural LDH and isoenzymes as additional diagnostic markers in pleural effusion. Thorax 1994; 199 (Suppl): 474
Saint-Remy P, Buret J, et al. Signification des LDH des epanchments pleuraux. Rev Pneumol Clin 1986; 42: 74-81
Tietz WH. Lactate dehydrogenase. In: Tietz WN, Bhagawan N (eds). Textbook of Clinical Chemistry. Philadelphia: WB Saunders Company, 1986: 691-8
Paavonen T, Liippo K, Aronen H, et al. LDH, creatine kinase and their isoenzymes in pleural effusions. Clin Chem 1991; 37: 1909-12
Drent M, Cobben NAM, Henderson RF, et al. usefulness of LDH and its isoenzymes as indicators of lung damage or inflammation. Eur Respir J 1996; 9: 1736-42
Wroblewski F, Wroblewski R. The clinical significance of LDH activity in serous effusions. Ann Intern Med 1958; 48: 813-22
Glick JH. Serum LDH and total LDH values in healh and disease and clinical evaluation of these tests by means of discriminant analysis. Am J Clin Pathol 1969; 52:320-8
Bansal SK, Kaw JL. LDH in macrophages and serum during the development of pulmonary silicosis in the rat. Toxicol Lett 1981; 7: 279-83
Hamm H. LDH in pleural effusion, a diagnostic aid. Chest 1992; 2: 296-302. 16.Vergnon JM. Analyse des isoenzymes de la LDH dans le diagnostic des epanchments pleuraux. Rev Pneumol Clin 1986; 42: 314-5
Light RW, Ball WC. LDH isoenzymes in pieural effusions. Am Rev Respir Dis 1973; 108: 660-4.