Journals / Tüberküloz ve Toraks / 2019 / Cilt: 67 - Sayı: 3

The role of interventional pulmonology in endobronchial metastasis of renal cell carcinoma

Renal hücreli karsinomun endobronşiyal metastazında girişimsel pulmonolojinin yeri

Pages
211–218
Publication Date
2022-11-06
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Endobronchial treatment procedures forendobronchial metastasis of renal cell carcinoma can be performed with low complication rates.

📌 3 Key Takeaways

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Objective & Hypothesis:The role of interventional pulmonology in endobronchial metastasis of renalcell carcinomaIntroduction: Although metastasis of extrapulmonary solid organ malignanttumors to the lungs is very common, endobronchial metastases are very rare.The most common extrapulmonary tumors that make endobronchial metastases are breast, kidney and colorectal carcinomas.Materials and Methods: In this study, we retrospectively examined the data ofeleven renal cell carcinoma patients who underwent endobronchial metastases in an eight-year period.Results: Ten of the patients were male and the mean age was 55 ± 1 (41-71)years.
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Key Findings & Data:The most common symptom was cough (45.5%, n= 5), on the otherhand 18.2% (n= 2) of the patients had no complaints.
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Conclusion & Impact:Endobronchial treatment procedures forendobronchial metastasis of renal cell carcinoma can be performed with low complication rates.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The role of interventional pulmonology in endobronchial metastasis of renalcell carcinomaIntroduction: Although metastasis of extrapulmonary solid organ malignanttumors to the lungs is very common, endobronchial metastases are very rare.The most common extrapulmonary tumors that make endobronchial metastases are breast, kidney and colorectal carcinomas.Materials and Methods: In this study, we retrospectively examined the data ofeleven renal cell carcinoma patients who underwent endobronchial metastases in an eight-year period.Results: Ten of the patients were male and the mean age was 55 ± 1 (41-71)years. The most common symptom was cough (45.5%, n= 5), on the otherhand 18.2% (n= 2) of the patients had no complaints. Right bronchial system,left bronchial system and tracheal distribution rates of endobronchial lesionswere 45.5% (n= 5), 63.6% (n= 7) and 27.3% (n= 3) respectively. The meantime from diagnosis of primary renal cell carcinoma to endobronchial metastases was 47.5 ± 32 (5.2-100.5) months. A total of twenty two interventionalprocedures were performed. All except one patient underwent endobronchialtreatment. Argon plasma coagulation was most commonly used as the endobronchial metastases option (n= 10, 100%). The mechanical resection (n= 6,60%), laser (n= 5, 50%), cryoextraction (n= 5, 50%) and cryotherapy (n= 4,40%) methods were used other than argon plasma coagulation. The meansurvival time was 19.4 ± 15.7 (3.2-40.5) months after endobronchial metastases and 54.0 ± 40.4 (8.7-107.6) months after renal cell carcinoma diagnosis.Conclusion: Extrathoracic malignancy that most metastasis to the airways is renal cell carcinoma. Endobronchial treatment procedures forendobronchial metastasis of renal cell carcinoma can be performed with low complication rates.

Özet

Giriş: Akciğer dışı solid organ tümörlerinin akciğerlere metastazı oldukça sık olmasına rağmen, endobronşiyal metastazları son derece nadirdir. En sık endobronşiyal metastaz yapan akciğer dışı tümörler meme, böbrek ve kolorektal karsinomlardır. Materyal ve Metod: Biz bu çalışmada, sekiz yıllık bir dönemde endobronşiyal metastaz yapmış 11 renal hücreli karsinom hastasının verilerini retrospektif olarak inceledik. Bulgular: Hastaların 10'u erkek ve ortalama yaşları 55 ± 1 (41-71) yıl idi. En sık başvuru şikayeti öksürük (%45.5, n= 5) olan hastaların %18.2 (n= 2)’sinde herhangi bir şikayet yoktu. Endobronşiyal lezyonların sağ bronşiyal sistem, sol bronşiyal sistem ve trakeadaki dağılım oranları sırasıyla %45.5 (n= 5), %63.6 (n= 7) ve %27.3 (n= 3) idi. Primer renal hücreli karsinom tanısından endobronşiyal metastaza kadar geçen ortalama süre 47.5 ± 32 (5.2-100.5) aydı. Toplam 22 girişimsel işlem yapıldı. Hastalardan birisi dışında hepsine endobronşiyal tedavi uygulandı. Endobronşiyal tedavide en sık argon plazma koagülasyon (n= 10, %100) kullanıldı. Argon plazma koagülasyon dışında mekanik rezeksiyon (n= 6, %60), lazer (n= 5,%50), kriyoekstraksiyon (n= 5, %50) ve kriyoterapi (n= 4, %40) kullanıldı. Ortalama sağkalım süresi, endobronşiyal metastazdan sonra 19.4 ± 15.7 (3.2-40.5) ay, renal hücreli karsinom tanısından sonra ise 54.0 ± 40.4 (8.7-107.6) aydı. Sonuç: Hava yollarına en sık metastaz yapan akciğer dışı malignite renal hücreli karsinomdur. Renal hücreli karsinomun endobronşiyal metastazı için endobronşiyal tedavi işlemleri düşük komplikasyon oranları ile yapılabilir.

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Cite This Article

DOĞAN, D., ÖZGÜL, M. A., TURAN, D., ÇETİNKAYA, E. (2022). The role of interventional pulmonology in endobronchial metastasis of renal cell carcinoma. Tüberküloz ve Toraks, Cilt: 67 - Sayı: 3, 211–218. https://ajindex.com/articles/618416

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