Journals / Tüberküloz ve Toraks / 2020 / Cilt: 68 - Sayı: 4

Polysomnographic, demographic and clinic differences between male and female obstructive sleep apnea patients

Obstrüktif uyku apneli kadın ve erkek hastalar arasında polisomnografik, demografik ve klinik açıdan farklılıklar

Pages
361–370
Publication Date
2022-11-06
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Meanwhile we want to emphasize that clini-cians need to take these factors into consideration while focusing on the diagnosis of OSAS in female patients.

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Objective & Hypothesis:ntroduction: The differences between both genders with Obstructive Sleep Apnea Syndrome (OSAS) which is often seen in males can be explained by means of certain polysomnographical parameters and demographical and clinical features.
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Key Findings & Data:Materials and Methods: This study has been carried out by including 100 females and 116 males, 216 patients in total, who were diagnosed with OSAS in the Sleep Laboratory of the Medicine Faculty, Ankara University between the years of 2011 and 2014.
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Conclusion & Impact:Meanwhile we want to emphasize that clini-cians need to take these factors into consideration while focusing on the diagnosis of OSAS in female patients.
🔬Design:Research Article
📍Scope:2011 Verileri
⚙️Variables:Domain Parameters

Abstract

ntroduction: The differences between both genders with Obstructive Sleep Apnea Syndrome (OSAS) which is often seen in males can be explained by means of certain polysomnographical parameters and demographical and clinical features. The aim of this research study is to research the gender dif-ferences in Turkish population in terms of polysomnographical parameters and demographical and clinical features, and to compare and contrast the results of this research with the results of literature. Materials and Methods: This study has been carried out by including 100 females and 116 males, 216 patients in total, who were diagnosed with OSAS in the Sleep Laboratory of the Medicine Faculty, Ankara University between the years of 2011 and 2014. The demographical information like the ages and the genders of all patients and the figures of the height, weight and body-mass index (BMI) have been recorded. The Epworth Sleepiness Scale (ESS) of pati-ents have also been recorded. Acquired by the polysomnography equipment, the polysomnographical data of all patients having the criteria of this study have been evaluated. Results: The average age of female patients, which is 57.2 ± 9.1 (the lowest-the highest), has been found to be meaningfully high (p< 0.05) when compa-red to the average age of male patients (50.9 ± 11.8). The body-mass index (BMI) averages of female patients, which are 35.4 ± 9.2, have been determi-ned to be high (p< 0.05) when compared to the body-mass index (BMI) average of male patients (32.5 ± 6.7). The total Apnea Hypopnea Index (AHI) of male patients have been found to be meaningfully higher than of the femae patients (p< 0.05). Mild and moderate OSAS in female patients have been observed at a higher rate than males. On the other hand, severe OSAS has been observed at a higher rate than females (p< 0.05). Likewise, while the average obstructive apnea time in male patients has been for 17 ± 5.8 seconds, the same figure has been for 14.5 ± 4.4 seconds (p< 0.05).Conclusion: As a result, in this study, we have observed that females suffering from OSAS are older and obese at a more rate and they have lower Apnea Hypopnea Index (AHI) than the males with OSAS. We have also distinguished that the symptoms related to OSAS of both genders are similar despite the lower Apnea Hypopnea Index of females. Meanwhile we want to emphasize that clini-cians need to take these factors into consideration while focusing on the diagnosis of OSAS in female patients.

Özet

Giriş: Obstrüktif uyku apne sendromu (OSAS), üst hava yollarının parsiyel ya da tam tıkanması sonucu, uyku sırasında oksijen desa-türasyonları ve uyku bölünmeleri ile sonuçlanan sık solunum durma epizodları ile karakterize bir hastalıktır. Bu çalışmada Türk popu-lasyonunda polisomnografik parametreler, demografik ve klinik özellikler açısından cinsiyet farklılıklarının araştırılması ve sonuçlarının literatürdeki sonuçlarla karşılaştırılması amaçlanmıştır.Materyal ve Metod: Çalışmaya 2011-2014 yılları arasında Ankara Üniversitesi Tıp Fakültesi Uyku Laboratuvarı’nda OSAS tanısı almış 100 kadın 116 erkek olmak üzere toplam 216 hasta dahil edilmiştir. Tüm hastaların yaş ve cinsiyet gibi demografik bilgileri ile boy, kilo ve beden kitle indeksi değerleri, horlama, gün içi aşırı uykululuk, tanıklı apne, sabah uyandığında baş ağrısı, baş-boyun terlemesi ve nefes darlığını içeren semptom kayıtları, PSG öncesi uygulanmış olan ESS sonuçları kaydedildi. Çalışma kriterlerine sahip olan tüm hastaların PSG verileri değerlendirildi.Bulgular: Kadın hastaların yaş ortalaması 57.2 ± 9.1 olup, erkek hastaların yaş ortalamasına (50.9 ± 11.8) göre anlamlı olarak yüksek bulunmuştur (p 0.05). Ortalama obstrüktif apne sayısına bakıldığında, erkek hastaların ortalaması 56 ± 129 olarak bulunmuş olup, kadın hastaların ortalamasına göre (32 ± 84.1) yüksek saptanmıştır (p< 0.05). Ortalama obstrüktif apne sürelerine bakıldığında da,erkek hastaların ortalaması 17 ± 5.8 olarak bulunmuş olup, kadın hastaların ortalamasına göre (14.5 ± 4.46) yüksek saptanmıştır (p< 0.05). OSAS’lı erkek hastalarda Total AHI OSAS’lı kadın hastalardan anlamlı olarak yüksek bulunmuş-tur (p< 0.05). AHI NREM erkek OSAS’lı kadınlarda, AHI REM ise kadın OSAS’lı hastalarda yüksek bulunmuş fakat her iki parametre için cinsiyetler arası istatistiksel anlamlı fark bulunmamıştır.Kadınlarda hafif ve orta derecedeki OSAS erkeklere göre daha yüksek oranda gözlenirken; ağır OSAS ise erkeklerde kadınlara göre daha yüksek oranda gözlenmiş olup, bu farklılıklar istatistiksel olarak anlamlı bulunmuştur (p< 0.05).Sonuç: OSAS’lı kadınların OSAS’lı erkeklerden daha yaşlı ve obez olduğunu, daha düşük AHI değerine sahip olduklarını, semptom-larının benzer olduğunu gözlemlerken, klinisyenlerin kadın hastalarda OSAS tanısını düşünürken bu faktörleri göz önüne almaları gerektiğini vurgulamak istedik.

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Cite This Article

ACICAN, T., GÜLBAY, B., IŞIK, M. E., ÇİFTCİ, F. (2022). Polysomnographic, demographic and clinic differences between male and female obstructive sleep apnea patients. Tüberküloz ve Toraks, Cilt: 68 - Sayı: 4, 361–370. https://ajindex.com/articles/618333

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