SavedAdd your journal

Journals / Turkish Journal of Veterinary and Animal Sciences / 2007 / Cilt: 31 - Sayı: 4

Japon bıldırcınlarında musculus longus colli dorsalis' in embriyonik gelişimiüzerinde in ovo insulin-benzeri büyüme faktörü-1'in etkileri

The effects of in ovo ınsulin-like growth factor-1 on embryonic development of musculus longus colli dorsalis in japanese quail

Turgay DEPREM
Nurhayat GÜLMEZ
Pages
223–240
Publication Date
2022-11-04
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It was concluded that •• rhIGF-1 accelerated skeletal muscle development in the quail embryos.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Abstract: The objective of the present study was to evaluate the effects of insulin-like growth factor-1 (IGF-1) on the histological development of the thoracic part of the m. longus colli dorsalis (m. spinalis thoracis) in Japanese quail embryos.
📊
Key Findings & Data:A single in ovo dose of recombinant human IGF-1 (rhIGF-1) (100 ng embryo"1) was administered through the blunt end of eggs via a single hole made with a dental drill bit, without penetrating the chorioallantoic membrane.
💡
Conclusion & Impact:It was concluded that •• rhIGF-1 accelerated skeletal muscle development in the quail embryos.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Abstract: The objective of the present study was to evaluate the effects of insulin-like growth factor-1 (IGF-1) on the histological development of the thoracic part of the m. longus colli dorsalis (m. spinalis thoracis) in Japanese quail embryos. A single in ovo dose of recombinant human IGF-1 (rhIGF-1) (100 ng embryo"1) was administered through the blunt end of eggs via a single hole made with a dental drill bit, without penetrating the chorioallantoic membrane. For histological evaluation, the embryos were collected daily from days 7 to 16 of embryonic development (E). In ovo administration of rhIGF-1 increased the diameter of muscle fibers on E7, 9, 10, 11, and 13. Additionally, in ovo rhIGF-1 also increased the number of muscle fibers (P < 0.001). It was concluded that •• rhIGF-1 accelerated skeletal muscle development in the quail embryos.

Özet

Özet: Bu çalışmanın amacı; Japon bıldırcını embriyolarının m. longus colli dorsalis (m. spinalis thoracis) kasının thoracic kısmının histolojik gelişiminde, insulin-benzeri büyüme faktörü-Tin etkilerini değerlendirmekti. Rekombinant insan IGF-l'i (rhIGF-1), yumurtanın küt ucunda, dental drill bit ile açılan delikten, bir defa olmak üzere 100 ng/her bir embriyo oranında chorio-allantoik membrana girmeksizin enjekte edildi. Histolojik değerlendirmeler için dokular, embriyonik gelişimin 7 ile 16. günleri arasında günlük olarak toplandı. RhIGF-1 uygulamasının embriyonik gelişimin 7, 9, 10, 11 ve 13. günlerinde kas tellerinin sayı ve çapında anlamlı bir artışa neden olduğu gözlendi (P < 0,001). Sonuç olarak; rhIGF-1'in Japon bıldırcını embriyolarının iskelet kası gelişimini hızlandırdığı sonucuna varıldı.

🔖

Cite This Article

DEPREM, T., GÜLMEZ, N. (2022). Japon bıldırcınlarında musculus longus colli dorsalis' in embriyonik gelişimiüzerinde in ovo insulin-benzeri büyüme faktörü-1'in etkileri. Turkish Journal of Veterinary and Animal Sciences, Cilt: 31 - Sayı: 4, 223–240. https://ajindex.com/articles/615409

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Swatland, H.J.: Physiology of muscle growth. In: Nixey, C, Grey, T.C., Eds. Recent Advances in Turkey Science. Butterworths, London. 1989; 167-182,
  2. McMurtry, J.P., Francis, G.L., Upton, Z.: Insulin-like growth factors in poultry. Domest. Anim. Endocrinol. 1997; 14: 199- 229
  3. Tollefsen, S.E., Lajara, R., McCusker, R.H., Clemmons, D.R., Rotwein, P.: Insulin-like growth factors (IGFs) in muscle development. Expression of 1GF-1, the IGF-1 receptor, and an IGF binding protein during myoblast differentiation. J. Biol. Chem., 1989:264:13810-13817
  4. Florini, J.R., Ewton, D.Z., Coolican, S.A.: Growth hormone and the insulin-like growth factor system in myogenesis. Endocr. Rev., 1996; 17:481-517
  5. Schwander, J.C., Hauri, C, Zapf, J., Froesch, E.R.: Synthesis and secretion of IGF-1 and its binding protein by the perfused rat liver: dependence on growth hormone status. Endocrinology. 1983; 113:297-305
  6. Tanaka, M., Hayashida, Y., Sakaguchi, K., Ohkubo, T., Wakita, M., Hoshino, S., Nakashima, K.: Growth hormone-independent expression of IGF-1 messenger RNA in extrahepatic tissues of the chicken. Endocrinology, 1996; 137: 30-34
  7. Florini, J.R., Nicholson, Ml., Dulak, N.C.: Effects of peptide anabolic hormones on growth of myoblasts " in culture. Endocrinology, 1977; 101: 32-41
  8. Ewton, D.Z., Florini, J.R.: Effects of somatomedins and insulin on myoblast differentiation in vitro. Dev. Biol., 1981; 86: 31-39
  9. Schmid, C, Steiner, T., Froesch, E.R.: Preferential enhancement of myoblast differentiation by IGF-1 and II in primary cultures of chick embryonic cells. FEBS Lett, 1983; 161: 117-121
  10. Dodson, M.V., Allen, R.E., Hossner, K.L.: Ovine somatomedin, multiplication-stimulating activity, and insulin promote skeletal muscle satellite cell proliferation in vitro. Endocrinology, 1985; 117:2357-2363
  11. Girbau, M., Gomez, J.A., Lesniak, M.A., de Pablo F.: Insulin and insulin-like growth factor-1 both stimulate metabolism, growth and differentiation in the post-neurula chick embryo. Endocrinology, 1987; 121:1477-1482
  12. Kocamis, H., Kirkpatrick-Keller, D.C., Klandorf, H., Killefer, J.: In ovo administration of recombinant human insulin-like growth factor-1 (rhlGF-1) alters postnatal growth and development of the broiler chicken. Poult. Sci., 1998; 77: 1913-1919
  13. Luna, L. G.: Manual of Histologic Staining Methods of the Armed Forces Institute of Pathology. New York, McGraw-Hill Book Comp, 3rd. ed., 72-100, 1968
  14. Minitab: Minitab Reference Ma