Journals / Turkish Journal of Surgery / 2019 / Cilt: 35 - Sayı: 3

Impact of routine histopathological examination of appendectomy specimens on patient management: a study of 4012 appendectomy specimens

Apendektomi örneklerinin rutin histopatolojik incelemesinin hasta yönetimine etkisi: 4012 apendektomi örneği

Pages
196–201
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Hence, all appendectomy specimens must be submitted for routine HPE.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: For a suspected diagnosis of acute appendicitis, appendectomy is one of the most common emergency abdominal operations performed.However, the need for routine histopathological examination (HPE) of all appendectomy specimens has recently been questioned.
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Key Findings & Data:The aim of thisstudy was to assess whether a routine HPE of appendectomy specimens is needed and whether routine HPE has an impact on further management ofpatients.Material and Methods: From January 2009 to June 2017, all histopathology reports of 4012 consecutive appendectomy specimens for a clinical suspicion of acute appendicitis were retrospectively analyzed in two university hospitals.Results: Out of the 4012 cases, 3530 (88%) patients showed findings consistent with acute appendicitis on HPE.
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Conclusion & Impact:Hence, all appendectomy specimens must be submitted for routine HPE.
🔬Design:Research Article
📍Scope:2009 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: For a suspected diagnosis of acute appendicitis, appendectomy is one of the most common emergency abdominal operations performed.However, the need for routine histopathological examination (HPE) of all appendectomy specimens has recently been questioned. The aim of thisstudy was to assess whether a routine HPE of appendectomy specimens is needed and whether routine HPE has an impact on further management ofpatients.Material and Methods: From January 2009 to June 2017, all histopathology reports of 4012 consecutive appendectomy specimens for a clinical suspicion of acute appendicitis were retrospectively analyzed in two university hospitals.Results: Out of the 4012 cases, 3530 (88%) patients showed findings consistent with acute appendicitis on HPE. Perforation rate was 5.8% and wassignificantly higher in male patients (p 30 years age group (p= 0.024). Negative appendectomy rate was 5.6% and was significantly higher in female patients (p< 0.001). There were 256 (6.4%) patients who demonstrated unusual findings in their HPE, which included chronicappendicitis (n= 207; 5.2%) patients, Enterobius vermicularis (n= 14), Schistosoma (n= 8), Crohn’s disease (n= 1), neuroma (n= 10), carcinoid tumour (n= 5)and mucinous cystadenoma (n= 5), mucocele (n= 4) and mucinous cystadenocarcinoma (n= 2).Conclusion: HPE of the appendix does not only confirm the diagnosis of acute appendicitis, but also detects other unusual diagnoses that may havean impact on a patient’s management. A number of patients with unusual histopathological findings require anti-helmentic treatment, colectomy,gastroenterology follow-up or periodic surveillance. Hence, all appendectomy specimens must be submitted for routine HPE.

Özet

Giriş ve Amaç: Akut apandisit tanısı şüphenilen durumlarda apendektomi en yaygın acil abdomen ameliyatlarından birini oluşturmaktadır. Ancak, tüm apendektomi örneklerinin rutin histopatolojik değerlendirilmesi (HPE) son yıllarda tartışılan bir konu olmuştur. Bu çalışmanın amacı, apendektomi örneklerine HPE yapılmasının gerekli olup olmadığını ve HPE’nin detaylı hasta yönetiminde bir etkiye sahip olup olmadığını ortaya koymaktı. Gereç ve Yöntem: Ocak 2009-Haziran 2017 tarihleri arasında akut apandisit klinik şüphesiyle 4012 ardışık apendektomi örneklerinin histopatolojik raporları iki üniversite hastanesinde retrospektif olarak incelendi. Bulgular: Toplam 4012 olgu içerisinde, 3530 (%88)’u, HPE’de akut apandisit ile uyumlu bulgular gösterdi. Perforasyon oranı %5,8 ve anlamlı derecede erkeklerde (p 30 yaş grubunda daha yüksekti (p= 0,024). Negatif apendektomi oranı %5,6 idi ve kadın hastalarda anlamlı şekilde daha yüksek bulundu (p< 0,001). 256 (%6,4) hastanın HPE’sinde olağandışı bulgulara rastlandı; bunlar sırasıyla kronik apandisit hastaları (n= 207; %5,2), Enterobius vermicularis (n= 14), Schistosoma (n= 8), Crohn’s hastalığı (n= 1), nöroma (n= 10), karsinoid tümör (n= 5), musinöz kistadenoma (n= 5), mukosel (n= 4) ve musinöz kistadenokarsinoma (n= 2) idi. Sonuç: Apandiste yapılan hem akut apandisit tanısını doğrular hem de hasta yönetimine etki edebilecek diğer olağandışı tanıları tespit eder. Olağandışı histopatolojik buğusu olan birkaç hasta anti-helmentik tedavi, kolektomi, gastroenteroloji takibi veya periyodik takip gerektirmektedir. Bu yüzden, tüm appendektomi örneklerine rutin HPE yapılmalıdır.

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Cite This Article

Benkhadoura, M., Elfaedy, O., Elshaikhy, A., Elgazwi, K. (2022). Impact of routine histopathological examination of appendectomy specimens on patient management: a study of 4012 appendectomy specimens. Turkish Journal of Surgery, Cilt: 35 - Sayı: 3, 196–201. https://ajindex.com/articles/614348

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