Journals / Turkish Journal of Surgery / 2020 / Cilt: 36 - Sayı: 1

Should there be a specific length of the colon-rectum segment to be resected for an adequate number of lymph nodes in cases of colorectal cancers? A retrospective multi-center study

Kolorektal kanserlerde yeterli lenf nodu sayısı için çıkarılacak kolon-rektum segmentinin belirli bir uzunluğu olmalı mı? Retrospektif çok merkezli bir çalışma

Pages
23–32
Publication Date
2022-11-06
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We conclude that the removed colonic size can be significant when performed with oncological surgical standardization.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: This study aimed to evaluate the question as to whether there should be a certain length of the colon-rectum segment to be resected forcorrect lymph node staging in cases with colorectal cancer.Material and Methods: The files and electronic datas of the patients had been undergone surgery for colorectal cancer between January 2011 andJune 2016 were evaluated.
📊
Key Findings & Data:The patients were divided into two groups; Group I= ≥ 12 lymph nodes, and Group II= lymph nodes less than 12 ( 21 cm.
💡
Conclusion & Impact:We conclude that the removed colonic size can be significant when performed with oncological surgical standardization.
🔬Design:Research Article
📍Scope:2011 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: This study aimed to evaluate the question as to whether there should be a certain length of the colon-rectum segment to be resected forcorrect lymph node staging in cases with colorectal cancer.Material and Methods: The files and electronic datas of the patients had been undergone surgery for colorectal cancer between January 2011 andJune 2016 were evaluated. The patients were divided into two groups; Group I= ≥ 12 lymph nodes, and Group II= lymph nodes less than 12 ( 21 cm. We conclude that the removed colonic size can be significant when performed with oncological surgical standardization.

Özet

Giriş ve Amaç: Bu çalışma, kolorektal kanserli olgularda doğru lenf nodu evrelemesi için rezeke edilecek kolon-rektum segmentinin belirli bir uzunluğunun olup olmadığı sorusunu değerlendirmeyi amaçlamaktadır. Gereç ve Yöntem: Kolorektal kanserli hastaların Ocak 2011-Haziran 2016 tarihleri arasında ameliyat geçiren dosyaları ve elektronik verileri değerlendirildi. Hastalar iki gruba ayrıldı; Grup I= ≥ 12 lenf nodu ve Grup II= 12’den az lenf nodu sayısı. Bulgular: Çalışmaya yaş ortalaması 64,30 ± 12,20 olan 327 olgu dahil edilmiştir. Rezeke edilen kolon-rektum segmentinin ortalama toplam uzunluğu 25,61 (± 14,07) cm; diseke edilen ortalama lenf nodu sayısı 20,63 ± 12,30 idi. Çıkarılan ortalama kolon-rektum uzunluğu Grup I’de 24 cm (145-6) ve Grup II’de 20 cm (52-9) olup gruplar arasında anlamlı fark bulunmuştur (p= 0,002). Yeterli lenf nodu diseksiyonu ile ilişkili faktörler; operasyonun türü (p= 0,001), tümör yeri (p= 0,005), tümör T evresi (p= 0,001), lenf nodunda metastaz durumu (p= 0,008) ve hastalığın evresi (p= 0,031) olarak bulunmuştur. Ortalama sağkalım 62,4 ± 1,31 ay idi. Grup I ve Grup II’de sırasıyla, 61,4 ± 1,39 ay ve 66,7 ± 3,25 idi (p= 0,449). Sonuç: Bu çalışma, çıkarılan kolon-rektum uzunluğu > 21 cm olduğunda ≥ 12 lenf nodu çıkarılabileceğini gösterdi. Çıkarılan bu kolon-rektum uzunluğunun onkolojik cerrahi standardizasyonuyla beraber yapıldığında anlamlı olacağını düşünüyoruz.

🔖

Cite This Article

KARAİSLİ, S., SAĞLAM, F., GÜVEN, H., ÜREYEN, O., ATAHAN, K. M., ULUSOY, C., ACAR, A., ALEMDAR, A., AYDIN, M. C., İLHAN, E., KIZILOĞLU, İ., DADALI, E. (2022). Should there be a specific length of the colon-rectum segment to be resected for an adequate number of lymph nodes in cases of colorectal cancers? A retrospective multi-center study. Turkish Journal of Surgery, Cilt: 36 - Sayı: 1, 23–32. https://ajindex.com/articles/614281

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (12)

  1. Lavy R, Madjar-Markovitz H, Hershkovitz Y, Sandbank J, Halevy A. Influence of colectomy type and resected specimen length on number of harvested lymph nodes. Int J Surg 2015
  2. [CrossRef] 2. Üstüner MA, İlhan E, Yeldan E, Argon A, Vardar E. Clinical and pathological factors affecting lymph node metastasis in patients operated on with the diagnosis of colorectal cancer. The Journal of Tepecik Education and Research Hospital 2016
  3. [CrossRef] 3. Gravante G, Parker R, Elshaer M, Mogekwu AC, Humayun N, Thomas K, et al. Lymph node retrieval for colorectal cancer: estimation of the minimum resection length to achieve at least 12 lymph nodes for the pathological analysis. Int J Surg 2016
  4. [CrossRef] 4. Rahbari NN, Bork U, Motschall E, Thorlund K, Büchler MW, Koch M, et al. Molecular detection of tumor cells in regional lymph nodes is associated with disease recurrence and poor survival in node-negative colorectal cancer: a systematic review and meta-analysis. J Clin Oncol 2012
  5. [CrossRef] 5. Han J, Noh KT, Min BS. Lymphadenectomy in colorectal cancer: therapeutic role and how many nodes are needed for appropriate staging? Curr Colorectal Cancer Rep 2017
  6. [CrossRef] 6. Edge SB, ComptonCC.The American Joint Committee on Cancer: the 7th edition of the AJCC cancer staging manual and the future of TNM. Ann Surg Oncol 2010
  7. [CrossRef] 7. Stracci F, Bianconi F, Leite S, Liso A, La Rosa F, Lancellotta V, et al. Linking surgical specimen length and examined lymph nodes in colorectal cancer patients. Eur J Surg Oncol (EJSO) 2016
  8. [CrossRef] 8. Tsai HL, Lu CY, Hsieh JS, Wu DC, Jan CM, Chai CY, et al. The prognostic significance of total lymph node harvest in patients with T2-4N0M0 colorectal cancer. J Gastrointest Surg 2007
  9. [CrossRef] 9. Matias EV, Leighton J, Tester W. Modifiable factors that influence colon cancer lymph node sampling and examination. Clin Col Cancer 2010
  10. [CrossRef] 10. Willaert W, Mareel M, Van De Putte D, Van Nieuwenhove Y, Pattyn P, Ceelen W. Lymphatic spread, nodal count and the extent of lymphadenectomy in cancer of the colon. Cancer Treat Rev 2014
  11. [CrossRef] 11. Stocchi LV, FazioW, Lavery I, Hammel J. Individual surgeon, pathologist, and other factors affecting lymph node harvest in stage II coloncarcinoma: is a minimum of 12 examined lymph nodes sufficient? Ann Surg Oncol 2011
  12. [CrossRef] 12. Neufeld D, Bugyev N, Grankin M, Gutman M, Klein E, Bernhe