AI Summary & Key Takeaways
AI InsightThe structures of the compoundswere elucidated by extensive 1D and 2D nuclear magnetic resonance spectroscopic analysis in combination with mass spectrometry experimentsand comparison with the relevant literature data.Results: This first phytochemical investigation on all parts of H. pastinaca Fenzl led to the isolation and identification of seven known flavonoidglycosides: isoquercetin (1), rutin (2), afzelin (3), astragalin (4), isorhamnetin 3-O-glucoside (5), nicotiflorin (6), and narcissoside (7).Conclusion: This is the first report on the isolation of these flavonoid glycosides from H. pastinaca and compounds 3, 5, 6, and 7 from the genusHeracleum.
📌 3 Key Takeaways
Abstract
Objectives: The objective was to isolate and characterize the secondary metabolites of Heracleum pastinaca, which has not been previouslyinvestigated.Materials and Methods: Conventional chromatographic procedures were carried out for isolation of the compounds. The structures of the compoundswere elucidated by extensive 1D and 2D nuclear magnetic resonance spectroscopic analysis in combination with mass spectrometry experimentsand comparison with the relevant literature data.Results: This first phytochemical investigation on all parts of H. pastinaca Fenzl led to the isolation and identification of seven known flavonoidglycosides: isoquercetin (1), rutin (2), afzelin (3), astragalin (4), isorhamnetin 3-O-glucoside (5), nicotiflorin (6), and narcissoside (7).Conclusion: This is the first report on the isolation of these flavonoid glycosides from H. pastinaca and compounds 3, 5, 6, and 7 from the genusHeracleum.
Özet
Amaç: Bu çalışmanın amacı, üzerinde daha önce herhangi bir fitokimyasal çalışma bulunmayan Heracleum pastinaca’nın sekonder bileşiklerinin izolasyonu ve karakterizasyonudur. Gereç ve Yöntemler: Maddelerin izolasyonları, klasik kromatografik prosedürlere göre yapılmıştır. Saf bileşiklerin yapıları, kütle spektrometresi deneyleri ile 1D ve 2D nükleer manyetik rezonans spektroskopik analizleri kullanılarak aydınlatılmış; literatür verileriyle de doğrulanmıştır. Bulgular: H. pastinaca Fenzl’in tüm kısımlarının ilk defa fitokimyasal açıdan incelenmesinde, yedi adet bilinen; izokersetin (1), rutin (2), afzelin (3), astragalin (4), izoramnetin 3-O-glukozit (5), nikotiflorin (6) ve narkisozit (7) isimli flavonoit glikozitleri izole edilerek tanımlanmıştır. Sonuç: Bu çalışma ile izole edilen flavonoitlerin tamamı, H. pastinaca’dan, 3, 5, 6, 7 nolu bileşikler ise Heracleum cinsinden ilk defa tanımlanmıştır.