Journals / Turkish Journal of Pharmaceutical Sciences / 2022 / Cilt: 19 - Sayı: 3

The Safety of Herbal Medicines (Phytovigilance) from Community Pharmacists’ Perspective: A Cross-Sectional Study

Pages
280–286
Publication Date
2022-11-02
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It was found that pharmacists with a working experience of more than 20 years primarily selected herbal products provided in their pharmacy based on the manufacturing company primarily, whereas others selected based on the efficacy of the products.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objectives: The “safe if natural” perception of herbal products may have several undesirable side effects.
📊
Key Findings & Data:The role of pharmacists is to supply herbal medicines safely and to provide accurate information to the patients about herbal products.
💡
Conclusion & Impact:It was found that pharmacists with a working experience of more than 20 years primarily selected herbal products provided in their pharmacy based on the manufacturing company primarily, whereas others selected based on the efficacy of the products.
🔬Design:Survey & Empirical Study
📍Scope:2019 Verileri
⚙️Variables:Domain Parameters

Abstract

Objectives: The “safe if natural” perception of herbal products may have several undesirable side effects. It is important to raise awareness in public order to change this perception and ensure safer use of herbal products. The role of pharmacists is to supply herbal medicines safely and to provide accurate information to the patients about herbal products. The aim of this study was to analyze the perspective, knowledge, attitude, and behavior of community pharmacists about phytovigilance. Materials and Methods: A cross-sectional analysis was performed using community pharmacists (n= 879) using face-to-face surveys between April-June 2019 in Istanbul. For statistical analysis, student’s t-test and one-way ANOVA were used to compare the mean values of the groups. Results: It was determined that 58.1% of the pharmacists heard phytovigilance for the first time and 93.5% of them had not reported any safety-related herbal medicine reported so far. Among the reasons for not reporting, well-known adverse reactions were found to be 24.2% and the difficulty of reporting was found to be 21.8%. 84.6% of pharmacists have never received training related to phytovigilance. It was found that pharmacists with a working experience of more than 20 years primarily selected herbal products provided in their pharmacy based on the manufacturing company primarily, whereas others selected based on the efficacy of the products. Conclusion: The results of this study have revealed the necessity to increase training on the safety of herbal medicines to cover all stakeholders and to give due importance to phytovigilance. The phytovigilance systems established in some countries for public health should be expanded to other countries. There is a need for a more user-friendly reporting system to increase adverse reaction reporting by pharmacists and other healthcare professionals. In the future, plan to perform studies to raise awareness in the public and promote reporting with digital technologies.

🔖

Cite This Article

MEMİŞOĞLU, M., OTLATICI, G. (2022). The Safety of Herbal Medicines (Phytovigilance) from Community Pharmacists’ Perspective: A Cross-Sectional Study. Turkish Journal of Pharmaceutical Sciences, Cilt: 19 - Sayı: 3, 280–286. https://ajindex.com/articles/613593

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (17)

  1. Verma A, Sharma A, Garg K. Herbal medicine and pharmacovigilance: a future prospective. Int J Pharm Life Sci. 2014;5:3413-3417
  2. Calixto JB. Efficacy, safety, quality control, marketing and regulatory guidelines for herbal medicines (phytotherapeutic agents). Braz J Med Biol Res. 2000;33:179-189
  3. World Health Organization. Pharmacovigilance for traditional medicine products: why and how?. 2018; (https://apps.who.int/iris/ handle/10665/259854)
  4. Toklu HZ. Pharmacovigilance of herbal medicine: herbavigilance. Adv Pharmacoepidemiol Drug Saf. 2016;5:1000208
  5. Shaw D. Toxicological risks of Chinese herbs. Planta Med. 2010;76:2012- 2018
  6. Shaw D, Graeme L, Pierre D, Elizabeth W, Kelvin C. Pharmacovigilance of herbal medicine. J Ethnopharmacol. 2012;140:513-518
  7. Bunchorntavakul C, Reddy KR. Review article: herbal and dietary supplement hepatotoxicity. Aliment Pharmacol Ther. 2013;37:3-17
  8. Moreira DDL, Teixeira SS, Monteiro MHD, De-Oliveira ACA, Paumgartten FJ. Traditional use and safety of herbal medicines. Rev Bras Farmacogn. 2014;24:248-257
  9. Rodrigues E, Barnes J. Pharmacovigilance of herbal medicines: the potential contributions of ethnobotanical and ethnopharmacological studies. Drug Saf. 2013;36:1-12
  10. De Smet PA. Health risks of herbal remedies. Drug Saf. 1995;13:81-93
  11. Nortier JL, Vanherweghem JL. For patients taking herbal therapylessons from aristolochic acid nephropathy. Nephrol Dial Transplant. 2007;22:1512-1517
  12. Perharic L, Shaw D, Leon C, De Smet PA, Murray VS. Possible association of liver damage with the use of Chinese herbal medicine for skin disease. Vet Hum Toxicol. 1995;37:562-566
  13. Dhami N, Mishra AD. Phytochemical variation: how to resolve the quality controversies of herbal medicinal products? J Herb Med. 2015;5:118-127
  14. Singh R, Kotecha M. A review on the standardization of herbal medicines. Int J Pharm Sci Res. 2016;7:97-106
  15. Antignac E, Nohynek GJ, Re T, Clouzeau J, Toutain H. Safety of botanical ingredients in personal care products/cosmetics. Food Chem Toxicol. 2011;49:324-341
  16. Mazzanti G, Vitalone A, Da Cas R, Menniti-Ippolito F. Suspected adverse reactions associated with herbal products used for weight loss: spontaneous reports from the Italian Phytovigilance system. Eur J Clin Pharmacol. 2019;75:1599-1615
  17. Lombardi N, Crescioli G, Bettiol A, Menniti-Ippolito F, Maggini V, Gallo E, Mugelli A, Vannacci A, Firenzuoli F. Safety of complementary and alternative medicine in children: a