Journals / Turkish Journal of Pharmaceutical Sciences / 2022 / Cilt: 19 - Sayı: 3

Potentially Inappropriate Medication Use in Older Adults with Chronic Kidney Disease

Pages
305–313
Publication Date
2022-11-02
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

There was a statistically significant difference in terms of prevalence among 3 criteria (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objectives: This study aimed to identify the prevalence of potentially inappropriate medication use (PIMU) in adults above the age of 65 with chronic kidney disease (CKD) according to the American Geriatric Society Beers Criteria (Beers), Screening Tool of Older People’s Potentially Inappropriate Prescriptions Criteria (STOPP) and medication appropriateness index (MAI) 30 criteria and to compare them to justify their use in this specific patient group.
📊
Key Findings & Data:Materials and Methods: This was a retrospective and descriptive study conducted between October 1st, 2019 and March 18th, 2020 at Ibni Sina Hospital, Nephrology Department, Faculty of Medicine, Ankara University.
💡
Conclusion & Impact:There was a statistically significant difference in terms of prevalence among 3 criteria (p
🔬Design:Research Article
📍Scope:2019 Verileri
⚙️Variables:Domain Parameters

Abstract

Objectives: This study aimed to identify the prevalence of potentially inappropriate medication use (PIMU) in adults above the age of 65 with chronic kidney disease (CKD) according to the American Geriatric Society Beers Criteria (Beers), Screening Tool of Older People’s Potentially Inappropriate Prescriptions Criteria (STOPP) and medication appropriateness index (MAI) 30 criteria and to compare them to justify their use in this specific patient group. Materials and Methods: This was a retrospective and descriptive study conducted between October 1st, 2019 and March 18th, 2020 at Ibni Sina Hospital, Nephrology Department, Faculty of Medicine, Ankara University. Results: Among 269 patients discharged from the hospital during the study period, 100 of them were eligible for the study. The mean age was 73.3 ± 6.9 years and 51.9% of them were male. The prevalence of 35 PIMU was 91%, 42%, and 70% according to the Beers, STOPP, and MAI criteria, respectively. There was a statistically significant difference in terms of prevalence among 3 criteria (p

🔖

Cite This Article

EYÜPOĞLU, Ş., ERTÜRK, Ş., PEHLİVANLI, A., SELÇUK, A., ÖZÇELİKAY, A. T. (2022). Potentially Inappropriate Medication Use in Older Adults with Chronic Kidney Disease. Turkish Journal of Pharmaceutical Sciences, Cilt: 19 - Sayı: 3, 305–313. https://ajindex.com/articles/613581

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (11)

  1. Centers for Disease Control and Prevention. Public health and aging: Trends in aging-United States and Worldwide. MM WR. 2003;52:101:6
  2. United Nations World Population Prospects. The 2017 revision. Key findings and advance tables. 2017. Accessed: 28 January 2021. Available from: https://esa.un.org/umpd/wpp/publications/files/wpp2017- keyfindings.pdf 3. Hudhra K, García-Caballos M, Jucja B, Casado-Fernández E, Espigares- Rodriguez E, Bueno-Cavanillas A. Frequency of potentially inappropriate prescriptions in older people at discharge according to Beers and STOPP criteria. Int J Clin Pharm. 2014;36:596-603
  3. Secora A, Alexander GC, Ballew SH, Coresh J, Grams ME. Kidney function, polypharmacy, and potentially inappropriate medication use in a community-based cohort of older adults. Drugs Aging. 2018;35:735-750
  4. Mallappallil M, Friedman EA, Delano BG, McFarlane SI, Salifu MO. Chronic kidney disease in the elderly: evaluation and management. Clin Pract (Lond). 2014;11:525-535
  5. CKD prevalence varies widely across European countries; dialysis prevalence skyrocketing worldwide. Accessed: 25 January 2021. Available from: https://www.kidneynews.org/kidney-news/researchadvances/ ckd-prevalence-varies-widely-across-european-countriesdialysis- prevalence-skyrocketing-worldwide#:~:text=The%20crude%20 stage%203%20to,to%2025.4%25%20in%20northeast%20Germany 7. Süleymanlar G, Utaş C, Arinsoy T, Ateş K, Altun B, Altiparmak MR, Ecder T, Yilmaz ME, Çamsari T, Başçi A, Odabas AR, Serdengeçti K. A population-based survey of chronic renal disease in Turkey-the CREDIT study. Nephrol Dial Transplant. 2011;26:1862-1871
  6. Zhang QL, Rothenbacher D. Prevalence of chronic kidney disease in population-based studies: systematic review. BMC Public Health. 2008;8:117
  7. Cadogan CA, Ryan C, Hughes CM. Appropriate polypharmacy and medicine safety: when many is not too many. Drug Saf. 2016;39:109-116
  8. Wooten JM. Pharmacotherapy considerations in elderly adults. South Med J. 2012;105:437-445
  9. Kaufmann CP, Tremp R, Hersberger KE, Lampert ML. Inappropriate prescribing: a systematic overview of published assessment tools. Eur J Clin Pharmacol. 2014;70:1-11
  10. By the 2019 American Geriatrics Society Beers Criteria® Update Expert Panel. American Geriatrics Society 2019 Updated AGS Beers Criteria® for potentially inappropriate medication use in older adults. J Am Geriatr Soc. 2019;67:674-694
  11. O’Mahony D. STOPP/START criteria for potentially inappropriate medications/pot