Journals / Turkish Journal of Obstetrics and Gynecology / 2021 / Cilt: 18 - Sayı: 2

Antenatal follow-up, anesthesia management and perinatal outcomes in pregnancy with renal transplant

Renal transplantlı gebelerin antenatal takibi, anestezi yönetimi ve perinatal sonuçları

Pages
109–114
Publication Date
2022-11-06
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Despite the presence of preterm delivery and comorbidities, antenatal/peripartum follow-up and analgesia/anesthesia management of renal transplant recipients revealed good perinatal outcomes.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Due to the recent increase in the successful pregnancies after renal transplant, the number of renal transplant recipients having vaginal or cesarean delivery possibly associated with high maternal, fetal and/or neonatal risk requiring team approach increased.
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Key Findings & Data:Materials and Methods: After ethics committee approval, renal transplant recipients who gave birth in our hospital between January 2010 and December 2019 were documented in this retrospective study.
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Conclusion & Impact:Conclusion: Despite the presence of preterm delivery and comorbidities, antenatal/peripartum follow-up and analgesia/anesthesia management of renal transplant recipients revealed good perinatal outcomes.
🔬Design:Research Article
📍Scope:2010 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: Due to the recent increase in the successful pregnancies after renal transplant, the number of renal transplant recipients having vaginal or cesarean delivery possibly associated with high maternal, fetal and/or neonatal risk requiring team approach increased. We aimed to evaluate antenatal follow-up, perinatal outcomes, and anesthesia management in pregnancies with renal transplantation and to compare them with the current literature. Materials and Methods: After ethics committee approval, renal transplant recipients who gave birth in our hospital between January 2010 and December 2019 were documented in this retrospective study. Demographic characteristics, comorbidities, antenatal follow-up, anesthesia management, and maternal, fetal, and neonatal outcomes were presented. Results: A total of 20 pregnant women who underwent renal transplant were identified. The mean age of the parturients was 31±5 years. The median interval from transplantation to conception was 8.15±4.8 years. Antenatal mean serum creatinine level and proteinuria were 1.48±1.39 mg/dL and 1.397±1.316 mg/dL, respectively. No allograft rejection was recorded. Comorbidities including hypertension (n=12), preeclampsia (n=6), and preterm delivery (n=10) were noted. The median gestational age was 35±3 weeks and the median newborn weight was 2.520±832 gram. There was one abortion, two pregnancy terminations, and 17 deliveries (3 vaginal and 14 cesareans). Cesarean sections (11/14; 78.6%) were mostly performed under spinal block and general anesthesia was performed in three (21.4%) women. Epidural analgesia for vaginal delivery was recorded in one parturient. Conclusion: Despite the presence of preterm delivery and comorbidities, antenatal/peripartum follow-up and analgesia/anesthesia management of renal transplant recipients revealed good perinatal outcomes.

Özet

Amaç: Son zamanlarda böbrek nakli sonrası başarılı gebeliklerin artması nedeniyle, yüksek maternal, fetal ve/veya neonatal risk ile ilişkili olarak ekip yaklaşımı gerektiren vajinal veya sezaryen doğum olan böbrek transplant alıcıları artmıştır. Renal transplantasyonlu gebeliklerde antenatal takibi, perinatal sonuçları ve anestezi yönetimini güncel literatürle karşılaştırmak için değerlendirmeyi amaçladık. Gereç ve Yöntemler: Etik kurul onayından sonra, Ocak 2010 - Aralık 2019 tarihleri arasında hastanemizde doğum yapan böbrek nakli alıcıları bu retrospektif çalışmada belgelendi. Demografik özellikler, komorbiditeler, antenatal takip, anestezi yönetimi ve maternal, fetal ve neonatal sonuçlar sunuldu. Bulgular: Böbrek nakli yapılan toplam 20 gebe belirlendi. Doğum yapanların ortalama yaşı 31±5 yıldı. Transplantasyondan gebe kalmaya kadar geçen medyan aralık 8,15±4,8 yıldı. Antenatal ortalama serum kreatinin düzeyi ve proteinüri sırasıyla 1,48±1,39 mg/dL ve 1,397±1,316 mg/dL idi. Allogreft reddi izlenmedi. Hipertansiyon (n=12), preeklampsi (n=6) ve erken doğum (n=10) gibi komorbiditeler izlendi. Ortanca gebelik yaşı 35±3 hafta ve ortanca yenidoğan ağırlığı 2,520±832 gramdı. Bir dilatasyon küretaj, 2 gebelik terminasyonu ve 17 doğum (3 vajinal ve 14 sezaryen) vardı. Sezaryenlerin çoğu (11/14; %78,6) spinal anestezi altında yapıldı ve üç (%21,4) gebeye genel anestezi uygulandı. Doğum eylemi ve vajinal doğum için epidural analjezi 1 gebede uygulandı. Sonuç: Preterm doğum ve komorbiditelerin varlığına rağmen, renal transplant alıcılarının antenatal/peripartum takibi ve analjezi/anestezi yönetimi iyi perinatal sonuçlar ortaya koydu.

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Cite This Article

Bayram, M., Günaydın, D. B., İnan, G., Turgut, E., Karçaaltıncaba, D., Büyükgebiz, B., Konca, S. (2022). Antenatal follow-up, anesthesia management and perinatal outcomes in pregnancy with renal transplant. Turkish Journal of Obstetrics and Gynecology, Cilt: 18 - Sayı: 2, 109–114. https://ajindex.com/articles/612916

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