Journals / Turkish Journal of Medical Sciences / 1998 / Cilt: 28 - Sayı: 2

Blood and fingernail copper (Cu) and magnesium (Mg) levels of chilldren with acute lymphoblastic leukemia

Pages
155–156
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The differences between serum Cu and fingernail Cu and Mg levels of the two groups were statistically significant which might be an index for the activity of the disease.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In this study, serum and fingernail Cu and Mg levels of 10 children with acute Iymphoblastic leukemia and 12 healthy children were determined.
📊
Key Findings & Data:Copper and magnesium levels of the sera and supernatants were measured by atomic ab-sorption spectrophotometer. (Perkin-Elmer 400).
💡
Conclusion & Impact:The differences between serum Cu and fingernail Cu and Mg levels of the two groups were statistically significant which might be an index for the activity of the disease.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

In this study, serum and fingernail Cu and Mg levels of 10 children with acute Iymphoblastic leukemia and 12 healthy children were determined. Copper and magnesium levels of the sera and supernatants were measured by atomic ab-sorption spectrophotometer. (Perkin-Elmer 400). Fingernail Cu and Mg levels of the patients were 8.67 ± 5.35 and 0.22 ± 0.12 $mu$mol/mg of nail respectively. The values for control subjects were 4.27 ± 2.32 and 0.14 ± 0.03 $mu$mol/mg of nail. Serum Cu and Mg levels of the patients were 525.1 ± 160.9 $mu$g/dl and 2.42 ± 0.54 mg/dl, and those of controls were 115.0 ± 70.7 $mu$g/dl and 2.20 ± 0.70 mg/dl respectively. The differences between serum Cu and fingernail Cu and Mg levels of the two groups were statistically significant which might be an index for the activity of the disease.

🔖

Cite This Article

AKKUŞ, İ., KAPTANOĞLU, B., ÇALIŞKAN, Ü., ÜNER, A., GÜRBİLEK, M. (2022). Blood and fingernail copper (Cu) and magnesium (Mg) levels of chilldren with acute lymphoblastic leukemia. Turkish Journal of Medical Sciences, Cilt: 28 - Sayı: 2, 155–156. https://ajindex.com/articles/612656

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (1)

  1. Aldor Y, Walach N, Modai D. Zinc andcopper levels in plasma, erythrocytesand whole blood in cancer patients.Klin Wonhenschr. 30:375-7, 1982. 2.Carpanteri, U., Myers. J., Thorpe, L.,Copper-zinc and iron in normal and leu-kemic Iymphocytes from children.Cencer Research. 46:981-4, 1986. 3.Ferandes, G., Nair, M., Onde, K., Im-pairement of cell mediated immunityfunctions by diatery zinc deficiency inmice. Proc. Natl. Acad. Sci. 76 (1),457-461,1979. 6.Tessmer, C.F., Hrgovic, M., Thomas,F.B., Longterm serum copper studies inacute leukemia in children. Cancer.30,35-65,1972. 7.Capel I.D., Pinnock. M.H., Wıllıams.D.C., The serum levels of some traceelements in cancer patients. Oncology.39,38-41,1982. 8.Ilıcan, G., Serum copper and mag-nesium levels in leukemia and ma-lignant Iymphoma. Lan-cet.6,1036.1971. 9.Van stekelenburg, G.J., Van de laar,A.J.B. Van Der Laag, J. Copper analysisof nail clippings: an attempt to dif-ferantiate between normal children andpatiens suffering from cystic fibrosis.Clin. Chim. Acta. 59,233.1975. 10.Osman, S., Gürgey, A., Zamani. V.P.,Changes in serum elements of child-hood acute Iymphoblastic leukemia be-fore and during therapy. Tur. J.Pediat.25 (4), 233-9 1983. 11.Hrgovic, M., Tessmer, C.F., Mınckler,T.M., Serum copper levels in Iymphomaand leukemia. Cancer. 21,743-755.1968