Journals / Turkish Journal of Medical Sciences / 1999 / Cilt: 29 - Sayı: 3

Decreasing Selenium Levels and Glutathione Peroxidase Activity in Patients With Cutaneous Leishmaniasis

Pages
291–295
Publication Date
2022-11-04
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Selenium concentrations and GSH-Px activities were found to be lower in the patient group than in the controls (p

📌 3 Key Takeaways

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Objective & Hypothesis:For most infectious diseases, increased formation of reactive oxygen species is secondary to the primary disease process.
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Key Findings & Data:Glutathione peroxidase (GSH-Px) remove H 2 O 2 , and selenium is requird for the activity of GSH-Px.
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Conclusion & Impact:Selenium concentrations and GSH-Px activities were found to be lower in the patient group than in the controls (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:cutaneous leishmaniasis · selenium · glutathione peroxidase

Abstract

For most infectious diseases, increased formation of reactive oxygen species is secondary to the primary disease process. Some microorganisms are highly susceptible to exogenous reactive oxygen species such as hydrogen peroxide. Glutathione peroxidase (GSH-Px) remove H 2 O 2 , and selenium is requird for the activity of GSH-Px. Therefore, to assess the status of GSH-Px and selenium in cutaneous leishmaniasis (CL), we determined serum selenium concentration and blood GSH-Px activity in 52 patients with CL and in 38 healthy controls. Selenium concentrations and GSH-Px activities were found to be lower in the patient group than in the controls (p

Özet

For most infectious diseases, increased formation of reactive oxygen species is secondary to the primary disease process. Some microorganisms are highly susceptible to exogenous reactive oxygen species such as hydrogen peroxide. Glutathione peroxidase (GSH-Px) remove H 2 O 2 , and selenium is requird for the activity of GSH-Px. Therefore, to assess the status of GSH-Px and selenium in cutaneous leishmaniasis (CL), we determined serum selenium concentration and blood GSH-Px activity in 52 patients with CL and in 38 healthy controls. Selenium concentrations and GSH-Px activities were found to be lower in the patient group than in the controls (p

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Cite This Article

KOÇYİĞİT, A., EREL, Ö., SEYREK, A., AVCI, S., AKTEPE, N., GÜR, S., GÜREL, M. S. (2022). Decreasing Selenium Levels and Glutathione Peroxidase Activity in Patients With Cutaneous Leishmaniasis. Turkish Journal of Medical Sciences, Cilt: 29 - Sayı: 3, 291–295. https://ajindex.com/articles/612470

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