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Journals / Turkish Journal of Medical Sciences / 2016 / Cilt: 46 - Sayı: 2

The role of human papilloma virus and herpes viruses in the etiology of nasal polyposis

Mücahide Esra KOÇOĞLU
Beyhan YILMAZ
Tayfun APUHAN
Şeyda ÖZSOY
Fırat Zafer MENGELOĞLU
Pages
310–314
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Thus, these viruses do not play a significant role in the formation of nasal polyps.

📌 3 Key Takeaways

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Objective & Hypothesis:Backround/aim: The aim of this study was to investigate the etiological role of human papilloma virus (HPV), herpes simplex virus (HSV), varicella-zoster virus (VZV), Epstein Barr virus (EBV), cytomegalovirus (CMV), and human herpes virus-6 (HHV-6) and -7 (HHV-7) in the occurrence of nasal polyposis.
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Key Findings & Data:Materials and methods: Nasal polyp samples from 30 patients with nasal polyposis and normal nasal mucosa from 10 patients without nasal polyps were obtained.
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Conclusion & Impact:Thus, these viruses do not play a significant role in the formation of nasal polyps.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Backround/aim: The aim of this study was to investigate the etiological role of human papilloma virus (HPV), herpes simplex virus (HSV), varicella-zoster virus (VZV), Epstein Barr virus (EBV), cytomegalovirus (CMV), and human herpes virus-6 (HHV-6) and -7 (HHV-7) in the occurrence of nasal polyposis. Materials and methods: Nasal polyp samples from 30 patients with nasal polyposis and normal nasal mucosa from 10 patients without nasal polyps were obtained. DNA was extracted from tissues. Real-time polymerase chain reaction was performed for all runs. Results: No HSV-1, HSV-2, or VZV was detected in the samples. Among the patient samples, EBV and HHV-7 DNA were detected in 18 (60%), HHV-6 was detected in 20 (66.7%), and HPV was detected in 4 (13.3%) samples. Among the controls, CMV DNA was positive in one (10%). EBV was positive in 5 (50%), HHV-6 and HHV-7 were positive in 7 (70%), and HPV was positive in 2 (20%) samples. No significant difference was found among the groups with any test in terms of positivity. Conclusion: The association of Herpesviridae and HPV with the pathogenesis of nasal polyps was investigated in this study and no relationship was found. Thus, these viruses do not play a significant role in the formation of nasal polyps.

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Cite This Article

KOÇOĞLU, M. E., YILMAZ, B., APUHAN, T., ÖZSOY, Ş., MENGELOĞLU, F. Z. (2022). The role of human papilloma virus and herpes viruses in the etiology of nasal polyposis. Turkish Journal of Medical Sciences, Cilt: 46 - Sayı: 2, 310–314. https://ajindex.com/articles/610793

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