Journals / Turkish Journal of Medical Sciences / 2020 / Cilt: 50 - Sayı: 2

Trends of sensitization to aeroallergens in patients with allergic rhinitis and asthma in the city of Bursa, South Marmara Sea Region of Turkey

Pages
330–336
Publication Date
2022-11-06
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Regional allergy panels may provide important clinical clues for characteristics and coursesof allergic diseases.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background/aim: Allergic rhinitis (AR) and asthma are the most common allergic disorders worldwide.
📊
Key Findings & Data:Weexamined the distribution of aeroallergen sensitizations detected by skin prick tests (SPTs) in adult patients with AR and/or asthma inthe city of Bursa.Materials and methods: Five hundred forty-five patients who underwent a SPT and were diagnosed with rhinitis and/or asthma inthe Uludağ University Faculty of Medicine’s Department of Immunology and Allergic Diseases Outpatient Clinic from March 2018 toAugust 2018 were retrospectively evaluated.
💡
Conclusion & Impact:Regional allergy panels may provide important clinical clues for characteristics and coursesof allergic diseases.
🔬Design:Research Article
📍Scope:2018 Verileri
⚙️Variables:Domain Parameters

Abstract

Background/aim: Allergic rhinitis (AR) and asthma are the most common allergic disorders worldwide. Aeroallergens are criticalcausative factors in the pathogenesis of these disorders and sensitization to aeroallergens differs in various countries and regions.Identification of the most common aeroallergen sensitization is crucial in the diagnosis and management of AR and asthma. Weexamined the distribution of aeroallergen sensitizations detected by skin prick tests (SPTs) in adult patients with AR and/or asthma inthe city of Bursa.Materials and methods: Five hundred forty-five patients who underwent a SPT and were diagnosed with rhinitis and/or asthma inthe Uludağ University Faculty of Medicine’s Department of Immunology and Allergic Diseases Outpatient Clinic from March 2018 toAugust 2018 were retrospectively evaluated. SPTs with standard extracts including house dust mites, pollens, molds, animal dander, andlatex were performed for patients.Results: A total of 545 patients were included and most of the patients (270; 49.5%) were between 30 and 49 years of age. The prevalenceof atopy was 57.9%. The most common aeroallergens detected in SPTs were Dermatophagoides farinae (50%) and D. pteronyssinus (44%),followed by grass-rye mix (43%), grass mix (38.6%), olive (33.2%), and wheat (32.3%). The sensitization to olive pollen was higher incases of mild asthma (52%), while sensitization to D. farinae was higher in patients with mild and moderate asthma (54.5%, 54.2%) (P< 0.05) .Conclusions: Our study revealed that house dust mite was the most common sensitizing aeroallergen in patients with AR and asthmawhile pollens were the most common allergen in patients with only AR. The sensitization to grass and olive pollen was higher in casesof mild asthma than moderate and severe. Regional allergy panels may provide important clinical clues for characteristics and coursesof allergic diseases.

🔖

Cite This Article

EDİGER, D., ŞEKER, Ü., ERBAY, M., GÜNAYDIN, F. E. (2022). Trends of sensitization to aeroallergens in patients with allergic rhinitis and asthma in the city of Bursa, South Marmara Sea Region of Turkey. Turkish Journal of Medical Sciences, Cilt: 50 - Sayı: 2, 330–336. https://ajindex.com/articles/610045

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (11)

  1. Asher MI, Montefort S, Bjorksten B, Lai CK, Strachan DP et al. Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry crosssectional surveys. Lancet 2006
  2. doi: 10.1016/ S0140-6736(06)69283-0 2. Chhabra SK, Gupta CK, Chhabra P, Rajpal S. Prevalence of bronchial asthma in school children in Delhi. Journal of Asthma 1998
  3. Reddel HK, Hurd SS, FitzGerald JM. World asthma day. GINA 2014: A global asthma strategy for a global problem. International Journal of Tuberculosis and Lung Disease 2014
  4. doi:10.5588/ijtld.14.0246 4. Ozergin Coskun Z, Celebi Erdivanlı O, Kazıkdas KC, Terzi S, Sahin U et al. High sensitization to house-dust mites in patients with allergic rhinitis in the eastern Black Sea region of Turkey: a retrospective study. American Journal of Rhinology & Allergy 2016
  5. doi: 10.2500/ajra.2016.30.4353 5. Farrokhi S, Gheybi MK, Movahed A, Tahmasebi R, Iranpour D et al. Common aeroallergens in patients with asthma and allergic rhinitis living in southwestern part of Iran: based on skin prick test reactivity. Iranian Journal of Allergy, Asthma and Immunology 2015
  6. 14 (2): 133. 6. Pazoki N, Ahmadi A, Mansori M, Mosavi Khorshidi SM, Onsori F et al. Prevalence of aeroallergens in patients with allergic rhinitis. Journal of Mazandaran University of Medical Sciences 2015
  7. 25 (125): 73-80. 7. Allen M, Heinzmann A, Noguchi E, Abecasis G, Broxholme J et al. Positional cloning of a novel gene influencing asthma from chromosome 2q14. Nature Genetics 2003
  8. doi: 10.1038/ng1256 8. Vercelli D. Discovering susceptibility genes for asthma and allergy. Nature Reviews Immunology 2008
  9. doi: 10.1038/nri2257 9. Illi S, Depner M, Genuneit J, Horak E, Loss G et al. Protection from childhood asthma and allergy in Alpine farm environments-the GABRIEL Advanced Studies. Journal of Allergy and Clinical Immunology 2012
  10. e6. doi:10.1016/j.jaci.2012.03.013 10. Marfortt DA, Josviack D, Lozano A, Cuestas E, Aguero L et al. Differences between preschoolers with asthma and allergies in urban and rural environments. Journal of Asthma 2018
  11. doi: 10.1080/02770903.2017.1339800 11. Dey D, Mondal P, Laha A, Sarkar T, Moitra S et al. Sensitization to common aeroallergens in the atopic population of West Bengal, India: an investigation by skin prick test. International Archives of A