Journals / Turkish Journal of Medical Sciences / 2020 / Cilt: 50 - Sayı: 2

Prognostic role of homeostasis model assessment and oral glucose tolerance test in nondiabetic patients with Bell’s palsy

Pages
405–410
Publication Date
2022-11-05
DOI
—
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⚡ TL;DR(Too Long; Didn't Read)

Recovery timewas significantly longer in prediabetics and newly diagnosed diabetic patients than in patients with normal glycemia (68 days, 52 days,and 32 days, respectively; P < 0.01).Conclusion: There is a strong linkage between HOMA-IR value and BP prognosis so HOMA-IR value may have a significant role ofpredicting BP prognosis at presentation.

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Objective & Hypothesis:Background/aim: We aimed to reveal the incidence and predictive role of insulin resistance and distorted oral glucose tolerance test innondiabetic patients with Bell’s Palsy (BP).Materials and methods: Eighty-six patients with BP and 28 control subjects; all with normal blood glucose levels and no history ofdiabetes, were enrolled in the study.
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Key Findings & Data:We investigated insulin resistance (IR) in all subjects, in terms of HOMA-IR greater than 2.7.
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Conclusion & Impact:Recovery timewas significantly longer in prediabetics and newly diagnosed diabetic patients than in patients with normal glycemia (68 days, 52 days,and 32 days, respectively; P < 0.01).Conclusion: There is a strong linkage between HOMA-IR value and BP prognosis so HOMA-IR value may have a significant role ofpredicting BP prognosis at presentation.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background/aim: We aimed to reveal the incidence and predictive role of insulin resistance and distorted oral glucose tolerance test innondiabetic patients with Bell’s Palsy (BP).Materials and methods: Eighty-six patients with BP and 28 control subjects; all with normal blood glucose levels and no history ofdiabetes, were enrolled in the study. We investigated insulin resistance (IR) in all subjects, in terms of HOMA-IR greater than 2.7. Sixtytwoof the patients also underwent an oral glucose tolerance test (OGTT).Results: The mean HOMA-IR value was significantly increased in patients, compared to the control group (3.2 vs 1.6; P < 0.01). IR wasdetected more in BP patients than in controls (P < 0.05). The patients with higher HOMA-IR values had more severe facial dysfunctionat the initial presentation and complete recovery time took longer than the patients with normal HOMA-IR value (75 days vs 42 days; P< 0.05). Following a 2h-OGTT, impaired glucose tolerance and newly diagnosed DM were found in 60% of the patients. Recovery timewas significantly longer in prediabetics and newly diagnosed diabetic patients than in patients with normal glycemia (68 days, 52 days,and 32 days, respectively; P < 0.01).Conclusion: There is a strong linkage between HOMA-IR value and BP prognosis so HOMA-IR value may have a significant role ofpredicting BP prognosis at presentation.

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Cite This Article

KORKMAZ, M. H., KESEROĞLU, K., KARAGÖZ, T., ÇAKAL, E., BAYIR, Ö., ÖZDEK, A., TATAR, E. Ç., ŞAHİN, M. (2022). Prognostic role of homeostasis model assessment and oral glucose tolerance test in nondiabetic patients with Bell’s palsy. Turkish Journal of Medical Sciences, Cilt: 50 - Sayı: 2, 405–410. https://ajindex.com/articles/609781

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References (4)

  1. Akyıldız N. Periferik Fasiyal Paraliziler ve Cerrahi Tedavisi. In: Akyıldız N (eds). Kulak Hastalıkları ve Mikrocerrahisi. 2.Cilt. Ankara, Türkiye: Bilimsel Tıp; 2002. pp.560-580 (in Turkish)
  2. Mattox DE. Clinical Disorders of the Facial Nerve. In: Flint PW, Haughey BH, Lund VJ, Niparko JK, Robbins KT, Thomas JR, Lesperance MM (eds). Cummings Otolaryngology: Head- Neck Surgery. 6th edition. Philadelphia, USA: Mosby Elsevier; 2015. pp. 2617-2628
  3. Maloney WJ. Bell’s palsy: the answer to the riddle of Leonardo da Vinci’s ‘Mona Lisa’. Journal of Dental Research 2011;90 (5): 580-582. doi: 10.1177/0022034510384629 4. Peitersen E. Bell’s Palsy: The spontaneous course of 2,500 peripheral facial nerve palsies of different etiologies. Acta Oto-Laryngologica 2002; 122 (7): 4-30. doi: 10.1080/000164802760370736 5. Gilden DH. Clinical practice. Bell’s palsy. The New England Journal of Medicine 2004; 351: 1323–1331
  4. Riga M, Kefalidis G, and Danielides V. The role of diabetes mellitus in the clinical presentation and prognosis of Bell palsy. Journal of the American Board of Family Medicine 2012; 25(6): 819-826. doi: 10.3122/jabfm.2012.06.120084 7. Vinik A, Mitchell B. Clinical aspects of diabetic neuropaties. Diabetes Metabolism Reviews 1988;4 (3): 223-253. doi: 10.1002/dmr.5610040304 8. Smith AG, Singleton JR. Impaired glucose tolerance and peripheral neuropathy. Neurologist 2008; 14: 24-29. doi: 10.1097/NRL.0b013e31815a3956 9. Smith AG, Singleton JR. The diagnostic yield of a standardized approach to idiopathic sensory-predominant neuropathy. Archives of Internal Medicine 2004; 164: 1021-1025. doi: 10.1001/archinte.164.9.1021 10. Smith AG, Russell J, Feldman EL, Goldstein J, Peltier A et al. Lifestyle intervention for pre-diabetic neuropathy. Diabetes Care 2006; 29 (6): 1294-1299. doi: 10.2337/dc06-0224 11. Bosco D, Plastino M, Bosco F, Consoli A, Labate A et al. Bell’s palsy: a manifestation of prediabetes? Acta Neurologica Scandinavica 2011; 123 (1): 68-72. doi: 10.1111/j.1600- 0404.2010.01365.x 12. Buysschaert M, Bergman M. Definition of prediabetes. Medical Clinics of North America 2011; 95 (2): 289-297. doi: 10.1016/j. mcna.2010.11.002 13. Kim B, Feldman EL. Insulin resistance in the nervous system. Trends Endocrinology Metabolism 2012; 23 (3): 133-141. doi: 10.1016/j.tem.2011.12.004 14. WHO expert consultation. Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. The Lancet 2004; 363 (9403): 157