Journals / Turkish Journal of Medical Sciences / 2022 / Cilt: 52 - Sayı: 3

Effects of iron deficiency on left ventricular functions in young women regardless of anemia: A speckle tracking echocardiography study

Pages
754–761
Publication Date
2022-11-06
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Patients with anemia (hemoglobin level

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background/aim: Iron deficiency is one of the most common metabolic disorders worldwide and affects multiple organs and systems including the cardiovascular (CV) system.
📊
Key Findings & Data:The aim of the study is to evaluate left ventricular (LV) functions in patients with low ferritin levels without anemia by two-dimensional “speckle tracking” echocardiography (2D STE).
💡
Conclusion & Impact:Patients with anemia (hemoglobin level
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background/aim: Iron deficiency is one of the most common metabolic disorders worldwide and affects multiple organs and systems including the cardiovascular (CV) system. Iron deficiency can cause structural and functional changes in the myocardium. The aim of the study is to evaluate left ventricular (LV) functions in patients with low ferritin levels without anemia by two-dimensional “speckle tracking” echocardiography (2D STE). Materials and methods: We studied 90 participants (all female) that were divided into two groups according to ferritin levels (49 patients with ferritin levels 30 ng/mL). Patients with anemia (hemoglobin level

🔖

Cite This Article

KILIÇ, A., ELÇİOĞLU, B. C., AYTEKİN, S., URAL, D., BAYDAR, O., TEFİK, N., HELVACI, F., GÜRSOY, E., DEMİRCİ, Y., AYTEKİN, V. (2022). Effects of iron deficiency on left ventricular functions in young women regardless of anemia: A speckle tracking echocardiography study. Turkish Journal of Medical Sciences, Cilt: 52 - Sayı: 3, 754–761. https://ajindex.com/articles/609227

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (12)

  1. Looker AC. Iron deficiency—United States, 1999–2000, The Journal of the American Medical Association 2002
  2. 288(17): 2114-2116. doi:10.1001/jama.288.17.2114-JWR1106-2-1 2. Miller JL. Iron deficiency anemia: a common and curable disease. Cold Spring Harbor Perspectives in Medicine 2013 Jul 1
  3. 3(7): a011866. doi: 10.1101/cshperspect.a011866 3. Andrews NC. Disorders of iron metabolism. New England Journal of Medicine 1999
  4. 1986–95. doi: 10.1056/ nejm.199912233412607 4. Klip IT, Comin-Colet J, Voors AA, Ponikowski P, Enjuanes C et al. Iron deficiency in chronic heart failure: an international pooled analysis. American Heart Journal 2013
  5. 575–82. doi: 10.1016/j.ahj.2013.01.017 5. Okonko DO, Mandal AK, Missouris CG, Poole-Wilson PA. Disordered iron homeostasis in chronic heart failure: prevalence, predictors, and relation to anemia, exercise capacity, and survival. Journal of the American College of Cardiology 2011
  6. 1241–51. doi: 10.1016/j.jacc.2011.04.040 6. Jankowska EA, Von Haehling S, Anker SD, Macdougall IC, Ponikowski P. Iron deficiency and heart failure: diagnostic dilemmas and therapeutic perspectives. European Heart Journal 2013
  7. 816–829. doi: 10.1093/eurheartj/ehs224 7. Blayney L, Bailey-Wood R, Jacobs A, Henderson A, Muir J. The effects of iron deficiency on the respiratory function and cytochrome content of rat heart mitochondria. Circulation Research 1976
  8. 744–748. doi.org/10.1161/01.res.39.5.744 8. Finch CA, Miller LR, Inamdar AR, Person R, Seiler K et al. Iron deficiency in the rat. Physiological and biochemical studies of muscle dysfunction. Journal of Clinical Investigation 1976
  9. 447–453. doi:10.1172/JCI108489 9. Petering DH, Stemmer KL, Lyman S, Krezoski S, Petering HG. Iron deficiency in growing male rats: a cause of development of cardiomyopathy. Annals of Nutrition and Metabolism 1990
  10. doi: 10.1159/000177592 10. Rineau E, Gaillard T, Gueguen N, Procaccio V, Henrion D et al. Iron deficiency without anemia is responsible for decreased left ventricular function and reduced mitochondrial complex I activity in a mouse model. International Journal of Cardiology 2018
  11. 206–212. doi: 10.1016/j.ijcard.2018.02.021 11. Dong F, Zhang X, Culver B, Chew HG, Kelley RO et al. Dietary iron deficiency induces ventricular dilation, mitochondrial ultrastructural aberrations and cytochrome c release: involvement of nitric oxide synthase and protein tyrosine nitration. Clinical Science 2005
  12. 277–286. doi:10.1042/ C