Journals / Turkish Journal of Endocrinology and Metabolism / 2022 / Cilt: 26 - Sayı: 2

A Giant Urinary Bladder Paraganglioma

Pages
100–102
Publication Date
2022-11-01
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Ours is the patient with largest reported case of urinary bladder paraganglioma and the only one managed with augmentation cystoplasty.

📌 3 Key Takeaways

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Objective & Hypothesis:Paragangliomas are catec holam ine-s ecret ing neuroendocrine tumors originating from extraadrenal neural crest cells.
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Key Findings & Data:We report a middle-aged female with a giant urinary bladder paraganglioma that was symptomatic for 6 years but unfortunately remained undiagnosed for more than half a decade.
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Conclusion & Impact:Ours is the patient with largest reported case of urinary bladder paraganglioma and the only one managed with augmentation cystoplasty.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Paragangliomas are catec holam ine-s ecret ing neuroendocrine tumors originating from extraadrenal neural crest cells. Urinary bladder paragangliomas are extremely rare and usually present with micturition-related hypertension, palpitations, headaches, dizziness, and sweating. We report a middle-aged female with a giant urinary bladder paraganglioma that was symptomatic for 6 years but unfortunately remained undiagnosed for more than half a decade. The patient exhibited the typical noradrenergic biochemical phenotype that characterizes paragangliomas. The patient was successfully managed with subtotal cystectomy and augmentation cystoplasty. Ours is the patient with largest reported case of urinary bladder paraganglioma and the only one managed with augmentation cystoplasty.

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Cite This Article

BASHİR, M. I., BABA, M. S., LONE, M. I., MİSGAR, R. A., WANİ, A. I., BHAT, A. H., KHAWAJA, A. R. (2022). A Giant Urinary Bladder Paraganglioma. Turkish Journal of Endocrinology and Metabolism, Cilt: 26 - Sayı: 2, 100–102. https://ajindex.com/articles/605316

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References (1)

  1. Leestma JE, Price EB Jr. Paraganglioma of the urinary bladder. Cancer. 1971;28(4):1063-1073. [CrossRef] 2. Cheng L, Leibovich BC, Cheville JC, et al. Paraganglioma of the urinary bladder: can biologic potential be predicted? Cancer. 2000;88(4):844- 852. [CrossRef] 3. Das S, Bulusu NV, Lowe P. Primary vesical pheochromocytoma. Urology. 1983;21(1):20-25. [CrossRef] 4. Deng JH, Li HZ, Zhang YS, Liu GH. Functional paragangliomas of the urinary bladder: a report of 9 cases. Chin J Cancer. 2010;29(8):729-734. [CrossRef] 5. Tsai CC, Wu WJ, Chueh KS, et al. Paraganglioma of the urinary bladder first presented by bladder bloody tamponade: two case reports and review of the literatures. Kaohsiung J Med Sci. 2011;27(3):108-113. [CrossRef] 6. Sawka AM, Jaeschke R, Singh RJ, Young Jr WF. A comparison of biochemical tests for pheochromocytoma: measurement of fractionated plasma metanephrines compared with the combination of 24-hour urinary metanephrines and catecholamines. J Clin Endocrinol Metab. 2003;88(2):553-558. [CrossRef] 7. Purandare NC, Sanghvi DA, Jhambekar NA. Pheochromocytoma of the urinary bladder. J Ultrasound Med. 2005;24(6):881-883. [CrossRef] 8. Wang H, Ye H, Guo A, et al. Bladder paraganglioma in adults: MR appearance in four patients. Eur J Radiol. 2011;80(3):e217-e220. [CrossRef] 9. Sunil N, John K, Nawahirsha S, Iyyadurai R. Micturition syncope: a rare presentation of bladder paraganglioma. BMJ Case Rep. 2020;13(9): e235353. [CrossRef] 10. Priyadarshi V, Pal DK. Paraganglioma of urinary bladder. Urol Ann. 2015;7(3):402-404. [CrossRef] 11. Ranaweera M, Chung E. Bladder paraganglioma: a report of case series and critical review of current literature. World J Clin Cases. 2014;2(10):591- 595. [CrossRef] 12. Juhlin CC, Zedenius J, Höög A. Clinical routine application of the secondgeneration neuroendocrine Markers ISL1, INSM1, and secretagogin in neuroendocrine neoplasia: staining outcomes and potential clues for determining tumor origin. Endocr Pathol. 2020;31(4):401-410. [CrossRef] 13. NGS in PPGL (NGSnPPGL) Study Group, Toledo RA, Burnichon N, et al. Consensus Statement on next- gener ation -sequ encin g-bas ed diagnostic testing of hereditary phaeochromocytomas and paragangliomas. Nat Rev Endocrinol. 2017;13(4):233-247. [CrossRef]