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AI Summary & Key Takeaways
AI Insight⚡ TL;DR(Too Long; Didn't Read)
Each of the three isolated triazoles was separately treated with benzyl chloride and with chloroacetic acid to furnish the corresponding benzylthio 5(a-c) and carboxymethylthio derivatives 6(a-c), respectively
📌 3 Key Takeaways
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Objective & Hypothesis:Intramolecular cyclization of the three isomeric 1,4-disubstituted thiosemicarbazides 3(a-c) in aqueous sodium hydroxide was attempted to obtain 2,4-dihydro-4-(2-phenylethyl)-5-(isomeric pyridyl)- 3H-1,2,4-triazole-3-thiones 4(a-c).
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Key Findings & Data:Intramolecular cyclization of the three isomeric 1,4-disubstituted thiosemicarbazides 3(a-c) in aqueous sodium hydroxide was attempted to obtain 2,4-dihydro-4-(2-phenylethyl)-5-(isomeric pyridyl)- 3H-1,2,4-triazole-3-thiones 4(a-c).
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Conclusion & Impact:Each of the three isolated triazoles was separately treated with benzyl chloride and with chloroacetic acid to furnish the corresponding benzylthio 5(a-c) and carboxymethylthio derivatives 6(a-c), respectively
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Abstract
Intramolecular cyclization of the three isomeric 1,4-disubstituted thiosemicarbazides 3(a-c) in aqueous sodium hydroxide was attempted to obtain 2,4-dihydro-4-(2-phenylethyl)-5-(isomeric pyridyl)- 3H-1,2,4-triazole-3-thiones 4(a-c). Each of the three isolated triazoles was separately treated with benzyl chloride and with chloroacetic acid to furnish the corresponding benzylthio 5(a-c) and carboxymethylthio derivatives 6(a-c), respectively
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Cite This Article
IQBAL, R., RAMA, N. H., ZAMANI, K. (2022). Synthesis of 2,4-dihydro-4-(2-phenylethyl)-5-(isomeric pyridyl)-3H-1,2,4-triazole-3-thiones and their derivatives. Turkish Journal of Chemistry, Cilt: 20 - Sayı: 4, 295–301. https://ajindex.com/articles/602655