Journals / Turkish Journal of Biology / 2018 / Cilt: 42 - Sayı: 6

Effectiveness of bitter melon extract in the treatment of ischemic wounds in rats

Pages
506–516
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It can be concluded that dressing with a bittermelon extract is more efficient in the treatment of wounds than using nitrofurazone or saline, and that dressing with olive oil accelerateswound healing, although not as much as dressing with bitter melon extract.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:There is no consensus on the properties of an ideal dressing for treating wounds.
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Key Findings & Data:A sample group of 48 rats was used in the trial.
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Conclusion & Impact:It can be concluded that dressing with a bittermelon extract is more efficient in the treatment of wounds than using nitrofurazone or saline, and that dressing with olive oil accelerateswound healing, although not as much as dressing with bitter melon extract.
🔬Design:Research Article
📍Scope:2014 Verileri
⚙️Variables:Domain Parameters

Abstract

There is no consensus on the properties of an ideal dressing for treating wounds. The aim of this study was to investigatethe efficacy of dressings using topically administered bitter melon extract with olive oil, pure olive oil, nitrofurazone, and saline in thehealing of ischemic wounds. A sample group of 48 rats was used in the trial. Their wounds were treated with bitter melon extract, pureolive oil, nitrofurazone, and saline. Data were collected between October 2014 and April 2015. The highest percentage (94.7%) of woundhealing was observed in the bitter melon extract group and the lowest percentage (86.3%) in the nitrofurazone group. At the end of the21st day, macroscopic reepithelialization was observed in 9 wounds in the bitter melon extract group (75%), in 6 wounds in the pureolive oil group (50%), and in only 3 wounds in the nitrofurazone and saline groups (25%). It can be concluded that dressing with a bittermelon extract is more efficient in the treatment of wounds than using nitrofurazone or saline, and that dressing with olive oil accelerateswound healing, although not as much as dressing with bitter melon extract.

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Cite This Article

KISACIK, Ö. G., GÜNEŞ, Ü., YAPRAKÇI, M. V., ALTUNBAŞ, K. (2022). Effectiveness of bitter melon extract in the treatment of ischemic wounds in rats. Turkish Journal of Biology, Cilt: 42 - Sayı: 6, 506–516. https://ajindex.com/articles/600257

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