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Journals / Turgut Özal Tıp Merkezi Dergisi / 2016 / Cilt: 23 - Sayı: 1

Diyabetik Ketoasidozla İlişkili Olası Bir Guillain-Barré Sendromu: Olgu Sunumu ve Literatürün Gözden Geçirilmesi

A Possible Guillain-Barre Syndrome Associated with Diabetic Ketoacidosis: A Case Report and Literature Review

Kemal BALCI
Hakan DOĞRU
Çetin KÜRŞAD AKPINAR
Pages
96–99
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Case reports of Guillain Barre Syndrome associated with diabetic ketoacidosis are rare in the literature.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Guillain-Barre Syndrome (GBS) is an acute inflammatory polyradiculoneuropathy.
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Key Findings & Data:Diabetic ketoacidosis (DKA) is a serious, life-threatening complication of Type 1 diabetes mellitus (DM).
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Conclusion & Impact:Case reports of Guillain Barre Syndrome associated with diabetic ketoacidosis are rare in the literature.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Guillain-Barre Syndrome (GBS) is an acute inflammatory polyradiculoneuropathy. Diabetic ketoacidosis (DKA) is a serious, life-threatening complication of Type 1 diabetes mellitus (DM). In the pathogenesis of Guillain-Barre Syndrome and DKA, autoimmunity plays a role. A thirty-five year old male patient, who had been followed up in endocrinology service with a diagnosis of diabetic ketoacidosis (DKA), complained of weakness in the arms and legs on the seventh day of hospitalization. The patient had no diseases except for diabetes mellitus type 1. The patient was diagnosed with Guillain Barre Syndrome (GBS) on the basis of neurological examination, cerebrospinal fluid results and electrophysiological findings. Clinical improvement was observed as a result of intravenous immunoglobulin therapy. Diabetic ketoacidosis induced GBS was considered for the patient. There is no study that points to diabetes mellitus or DKA as risk factors for GBS. Case reports of Guillain Barre Syndrome associated with diabetic ketoacidosis are rare in the literature.

Özet

Guillain Barre Sendromu (GBS) akut inflamatuvar bir poliradikülonöropatidir. Diyabetik ketoasidozis (DKA) ciddi, hayatı tehdit edici tip 1 diyabetes mellitusun (DM) komplikasyonudur. Guillain Barre sendromu ve diyabetik ketoasidozus patogenezinde otoimmunite rol alır. Otuzbeş yaşında erkek hasta diyabetik ketoasidoz tanısıyla endokrinoloji servisinde izlenmekte iken yatışının 7. gününde kol ve bacaklarında güçsüzlük yakınması gelişti. Tip 1 diyabetes mellitus dışında bilinen bir hastalığı yoktu. Nörolojik muayene, beyin omurilik sıvısı ve elektrofizyolojik bulgular ile Guillain-Barré Sendromu tanısı konuldu. İntravenöz immunglobulin tedavisi ile klinikte düzelme izlendi. Olgumuz da DKA'un tetiklediği GBS düşünülmüştür. Guillain Barre sendromu risk faktörü olarak diyabetes mellitus veya DKA'u işaret eden bir çalışma yoktur. Literatürde çok az sayıda olgumuza benzer vaka sunumları vardır

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Cite This Article

BALCI, K., DOĞRU, H., AKPINAR, Ç. K. (2022). Diyabetik Ketoasidozla İlişkili Olası Bir Guillain-Barré Sendromu: Olgu Sunumu ve Literatürün Gözden Geçirilmesi. Turgut Özal Tıp Merkezi Dergisi, Cilt: 23 - Sayı: 1, 96–99. https://ajindex.com/articles/599024

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