Results: Serum antioxidant levels and glutathione peroxidase activity in rats given curcumin were significantly higher than those of the control group (p
📌 3 Key Takeaways
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Objective & Hypothesis:Objectives: The purpose of the study was to examine the possible effects of curcumin on the formation of neomucosa in parietal peritoneum which was applied as a patch for terminal ileal defect in rats.
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Key Findings & Data:The control group was injected with saline and cur- cumin (2 mL/kg/day, by gavage) was given to the experimental group.
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Conclusion & Impact:Results: Serum antioxidant levels and glutathione peroxidase activity in rats given curcumin were significantly higher than those of the control group (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Abstract
Objectives: The purpose of the study was to examine the possible effects of curcumin on the formation of neomucosa in parietal peritoneum which was applied as a patch for terminal ileal defect in rats. Methods: Sixteen male Wistar Hannover rats were split into two groups. The control group was injected with saline and cur- cumin (2 mL/kg/day, by gavage) was given to the experimental group. In both groups, amounts of 8-hydroxy-2’-deoxyguanosine (8-OHdG) and malondialdehyde (MDA), the activities of glutathione peroxidase and superoxide dismutase were determined in serum. The development of neomucosa formation was examined morphologically. Results: Serum antioxidant levels and glutathione peroxidase activity in rats given curcumin were significantly higher than those of the control group (p
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Cite This Article
Solmaz, A., Yavuz, E., Hacim, N. A., Akbas, A., Gulcicek, O. B., Meric, S., Yigitbas, H., Ulgen, Y., Ercan, G., Celik, A., Kirankaya, A. (2022). Curcumin Enhanced the Neomucosa Formation by Mediating the Antioxidation Mechanism in Rats. Şişli Etfal Hastanesi Tıp Bülteni, Cilt: 56 - Sayı: 1, 154–160. https://ajindex.com/articles/594626
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